Results 1 to 10 of about 12,707 (116)

HYPOChLorous Acid TEsting Studies in elective groin VASCULAR surgery (HYPOCLATES:VASCULAR): protocol for an ambispective cohort study evaluating a standard change to hypochlorous acid lavage in patients undergoing elective groin vascular surgery [PDF]

BMC Surgery
Background Surgical site infections remain a frequent and clinically relevant complication following elective open vascular groin surgery, particularly in procedures involving implantation of alloplastic material.
Mika P. Nadvornik, Jonathan Uhl, Tobias Hoch Al Hessen, Niels Siegel, Axel Kramer, Christoph W. Michalski, Dittmar Böckler, Katrin Meisenbacher, Julian C. Harnoss   +8 more
doaj   +2 more sources

A Bifunctional Fluorescence Probe for the Detection of Hypochlorous Acid and Viscosity in Living Cells and Zebrafish [PDF]

Molecules
As two significant indicators in the microenvironment, hypochlorous acid and viscosity play important roles in multitudinous physiological metabolic processes.
Xin Zhang, Yanmei Si, Xinpeng Chen, Xuqing Nie, Yiheng Zhang, Li Lin, Yehao Yan   +6 more
doaj   +2 more sources

Comparative efficacy of eyelid cleansing wipes, hypochlorous acid, and saline for blepharitis-associated ocular surface disease: a randomized trial [PDF]

Scientific Reports
Blepharitis and meibomian gland dysfunction (MGD) commonly cause ocular surface symptoms, but comparative evidence for commonly used eyelid-cleansing strategies remains limited.
Ruijia Shi, Yihan Guo, Ao Li, Lei Tian, Ying Jie   +4 more
doaj   +2 more sources

Hypochlorous Acid (HOCl) as a Promising Respiratory Antiseptic [PDF]

Viruses
The COVID-19 pandemic has inflicted unprecedented pressure on communities and healthcare systems around the world. An outstandingly broad and intensive investigation of possible therapeutic interventions is currently taking place to prevent similar ...
Michael Winter, Dirk Boecker, Wilfried Posch   +2 more
doaj   +2 more sources

Effect of Stabilized Hypochlorous Acid on Re-epithelialization and Bacterial Bioburden in Acute Wounds: A Randomized Controlled Trial in Healthy Volunteers

Acta Dermato-Venereologica, 2022
The aim of this randomized controlled trial was to evaluate the wound-healing effect and antimicrobial properties of a novel stabilized hypochlorous acid solution on acute wounds, using a suction blister wound model. One suction blister was raised and de-
Ewa A. Burian, Lubna Sabah, Klaus Kirketerp-Møller, Glenn Gundersen, Magnus S. Ågren   +4 more
doaj   +1 more source

Research Progress of Small Molecule Fluorescent Probes for Detecting Hypochlorite

Sensors, 2021
Hypochlorous acid (HOCl) generates from the reaction between hydrogen peroxide and chloride ions via myeloperoxidase (MPO)-mediated in vivo. As very important reactive oxygen species (ROS), hypochlorous acid (HOCl)/hypochlorite (OCl−) play a crucial role
Zhi-Guo Song, Qing Yuan, Pengcheng Lv, Kun Chen   +3 more
doaj   +1 more source

Candida albicans resistance to hypochlorous acid

mBio, 2023
Innate immune cells, especially neutrophils, play key roles in protecting against infection by Candida albicans and other fungal pathogens. A distinct aspect of neutrophils compared to other phagocytes is that they make much higher levels of ...
Lois M. Douglas, Kyunghun Min, James B. Konopka   +2 more
doaj   +1 more source

Inactivation of SARS-CoV-2 and influenza A virus by dry fogging hypochlorous acid solution and hydrogen peroxide solution.

PLoS ONE, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is transmitted mainly by droplet or aerosol infection; however, it may also be transmitted by contact infection.
Masahiro Urushidani, Akira Kawayoshi, Tomohiro Kotaki, Keiichi Saeki, Yasuko Mori, Masanori Kameoka   +5 more
doaj   +1 more source

Hypochlorous acid hygiene solution in patients affected by blepharitis: a prospective randomised study

BMJ Open Ophthalmology, 2023
Background/aims To investigate the clinical outcomes and antimicrobial activity of an hypochlorous acid hygiene solution compared with hyaluronic acid wipes for blepharitis treatment in patients with dry eye disease (DED).Methods This study involved 48 ...
Rita Mencucci, Eleonora Favuzza, Alberto Morelli, Angelo Galano, Anna Maria Roszkowska, Michela Cennamo   +5 more
doaj   +1 more source

Hypochlorous acid-mediated modification of cholesterol and phospholipid: analysis of reaction products by gas chromatography-mass spectrometry.

Journal of Lipid Research, 1993
Oxidative modification of membrane lipids by hypochlorous acid could be an important element in the mechanism of membrane disruption by activated neutrophils. We have previously shown that hypochlorous acid reacts with unsaturated fatty acids of membrane
JJ van den Berg, CC Winterbourn, FA Kuypers   +2 more
doaj   +1 more source