Results 21 to 30 of about 2,520,373 (232)
Modification of IL-6 by hypochlorous acid: effects on receptor binding and possible role in treatment of COVID-19 [PDF]
, 2021 Interleukin-6 (IL-6) has been implicated in the pathogenesis of acute inflammatory events in COVID-19 patients. We exposed IL-6 to hypochlorous acid (HOCl) in vitro at concentrations reported to develop in vivo.
Erika, Keim +6 more
core +1 more source
Hypochlorous Acid: A Novel Agent Against Echinococcus granulosus Protoscoleces [PDF]
, 2023 Objective: We aimed to determine the scolicidal effect of hypochlorous acid and its efficiency at different concentrations. Materials and Methods: We tested the effectiveness of hypochlorous acid in-vitro on sterile gauze at different concentrations in ...
Alkan, Sevil +9 more
core +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal
Periodontology 2000, EarlyView., 2023 Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra +3 more
wiley +1 more source
Reactions of kynurenic acid with hypobromous acid and hypochlorous acid
Journal of Clinical Biochemistry and Nutrition, 2021 Kynurenic acid, a tryptophan metabolite, acts as antagonist or agonist of several receptors. Hypobromous acid (HOBr) and hypochlorous acid (HOCl) are generated by eosinophils and neutrophils. At inflammation sites, kynurenic acid may encounter HOBr and HOCl to generate products.
Suzuki, Toshinori +2 more
openaire +3 more sources
Time to rethink medical disinfection from a planetary health perspective
Journal of Global Health Reports, 2023 Disinfection products can have substantial environmental impacts which include associated manufacturing emissions, toxicity to marine life and potential adverse health outcomes. Despite this, disinfection is under-represented in sustainability approaches.
Kate M Homyer, Felicity V Mehendale
doaj +1 more source
Redox Biology, 2019 Calprotectin, the major neutrophil protein, is a critical alarmin that modulates inflammation and plays a role in host immunity by strongly binding trace metals essential for bacterial growth.
Teagan S. Hoskin +8 more
doaj +1 more source
Hypochlorous acid inactivates myeloperoxidase inside phagocytosing neutrophils
Redox Biochemistry and Chemistry, 2023 When neutrophils phagocytose bacteria, they release myeloperoxidase (MPO) into phagosomes to catalyse the conversion of superoxide to the potent antimicrobial oxidant hypochlorous acid (HOCl).
Martina Paumann-Page +8 more
doaj +1 more source
Chlorination and oxidation of heparin and hyaluronan by hypochlorous acid and hypochlorite anions: effect of sulfate groups on reaction pathways and kinetics. [PDF]
, 2013 Hypochlorous acid (HOCl), produced in inflammatory conditions by the enzyme myeloperoxidase, and its anion hypochlorite (OCl(-)) exist in vivo at almost equal concentrations.
Parsons, BJ +4 more
core +1 more source
Angewandte Chemie, EarlyView.Carbonate species play a previously overlooked role in near‐neutral seawater electrocatalysis. By coupling electrochemical hydrodynamics with mesoscopic simulations, we reveal a plausible carbonate‐mediated route in which carbonate functions as an interfacial proton acceptor and water as the oxygen donor, showing a possible mechanistic picture of ...
Miao Wang +2 more
wiley +2 more sources