Results 51 to 60 of about 14,838 (224)

Hypochlorous acid versus normal saline solution for the cleansing of indeterminate-depth burn wounds: a randomized, controlled trial

open access: yesBurns Open
Hypochlorous acid is an effective agent for wound irrigation, however, evidence from controlled trials involving burn wounds is lacking. This was a randomized, controlled study that compared healing outcomes, for indeterminate-depth burn wounds ...
Nantaporn Namviriyachote   +5 more
doaj   +1 more source

HOCl Responsive Lanthanide Complexes Using Hydroquinone Caging Units

open access: yesMolecules, 2020
Redox biology is still looking for tools to monitor redox potential in cellular biology and, despite a large and sustained effort, reliable molecular probes have yet to emerge.
Elena Del Giorgio, Thomas Just Sørensen
doaj   +1 more source

Disinfection Applications of On-Site Hypochlorous Acid Production [PDF]

open access: yes, 2023
Hypochlorous acid (HOCl) is a weak acid, but strong oxidizing agent produced naturally in the human body to fight viruses and bacteria. Hypochlorous acid can be produced by electrolysis of sodium chloride and water enabling local production of ...
Ngabanyi Sebagisha, Deborah
core   +1 more source

The Use of Hypochlorous Acid Lavage to Treat Infected Cavity Wounds

open access: yesPlastic and Reconstructive Surgery, Global Open, 2020
Summary:. Managing cavity wounds that cannot be cleaned using standard irrigating solution is challenging. An immunocompromised patient with a horseshoe perianal abscess was selected to represent a heavy infection in cavity wounds.
Apinut Wongkietkachorn, MD   +4 more
doaj   +1 more source

The Action of Hypochlorous Acid on Rubber [PDF]

open access: yes, 1934
It has been previously observed that when rubber latex is treated with cold aqueous hypochlorous acid, the simple additive attachment of the hypochlorous acid molecule at the ethylenic center of each C5H8 unit of the rubber molecule may be accompanied by
E. H. Farmer, G. F. Bloomfield
core   +1 more source

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

open access: yesAdvanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo   +7 more
wiley   +1 more source

Systematic Position Mapping of Split CRISPR‐Cas12a Activators Enables Highly Sensitive miRNA Detection and Cancer Cell Stratification

open access: yesAdvanced Science, EarlyView.
ABSTRACT Amplification‐free Cas12a diagnostics with split crRNA enable rapid and programmable target recognition, yet insufficient understanding of DNA activator architecture prevents predictable control over trans‐cleavage activity and sensitivity. Here we systematically map over 200 split DNA activator configurations by introducing nicks at every ...
Xiaoyan Tang   +8 more
wiley   +1 more source

Hypochlorous acid inhibits glutathione S-conjugate export from human erythrocytes [PDF]

open access: yes, 2002
It was found that the hypochlorous acid (HOCl) inhibits the active efflux of glutathione S-conjugates, 2,4-dinitrophenyl-S-glutathione (DNP-SG, c50%=258±24 μM HOCl) and bimane-S-glutathione (B-SG, c50%=125±16 μM HOCl) from human erythrocytes, oxidises ...
Soszyński, Mirosław   +11 more
core   +1 more source

Reactions of Methotrexate with Hypobromous Acid and Hypochlorous Acid

open access: yesChemical and Pharmaceutical Bulletin, 2019
Methotrexate is a folate antagonist cytotoxic drug employed in the therapy of cancers and rheumatoid arthritis. Hypobromous acid (HOBr) and hypochlorous acid (HOCl) are generated by eosinophils and neutrophils at inflammation sites. The administered methotrexate may encounter HOBr and HOCl, and react with them to generate products.
Suzuki, Toshinori, Takeuchi, Rie
openaire   +2 more sources

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

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