Results 81 to 90 of about 4,202 (211)

Comparative Effect of Standard Versus Extended Interval Dosing of Rituximab or Ocrelizumab in Multiple Sclerosis

Annals of Clinical and Translational Neurology, Volume 12, Issue 10, Page 2086-2096, October 2025.
ABSTRACT Objective We aimed to investigate the comparative effectiveness of standard versus personalized extended interval dosing of anti‐CD20 therapy on clinical and sub‐clinical outcomes in multiple sclerosis. Methods Clinical information was collected prospectively on Research Electronic Data Capture.
Nabil K. El Ayoubi, Fares Fahd, Hani Tamim, Salem Hannoun, Mark Bal, Elham El‐Hallak, Samia J. Khoury   +6 more
wiley   +1 more source

Acquired common variable hypogammaglobulinaemia and lymphoedema [PDF]

Postgraduate Medical Journal, 1988
Summary Two patients with lymphoedema of the legs developed recurrent respiratory infections and were found to have panhypogammaglobulinaemia. The early recognition and treatment of this form of immunity deficiency in patients with lymphoedema is important in order to prevent recurrent infections which could cause pulmonary damage and ...
S, Lozewicz, G, Morris, N, Garbett, N, Browse, B, Slavin, P, Cole   +5 more
openaire   +2 more sources

Are We Ready With Prevention for Type 1 Diabetes?

Diabetes/Metabolism Research and Reviews, Volume 41, Issue 7, October 2025.
ABSTRACT Definitive prevention for type 1 diabetes (T1D) is not yet available, but we are now entering a new era where disease‐modifying therapies are becoming available in T1D to halt disease progression. In this review, we present up‐to‐date knowledge related to the prevention of T1D in youth, involving disease‐modifying therapies at different T1D ...
Evelina Maines, Roberto Franceschi, Francesca di Candia, Enza Mozzillo   +3 more
wiley   +1 more source

Human Microsporidial Infections [PDF]

, 2006
Microsporidia are eukaryotic, spore forming obligate intracellular parasites, first recognised over 100 years ago. Microsporidia are becoming increasingly recognised as infectious pathogens causing intestinal and extra-intestinal diseases in both immuno ...
D D, Duhlinska, G I, Anyanwu, I CJ, Omalu, P U, Inyama, V A, Pam   +4 more
core  

IgM Augments Complement Bactericidal Activity with Serum from a Patient with a Novel CD79a Mutation [PDF]

, 2018
Antibody replacement therapy for patients with antibody deficiencies contains only IgG. As a result, concurrent IgM and IgA deficiency present in a large proportion of antibody deficient patients persists.
Burg, M. (Mirjam) van der, Flier, M. (Michiel) van der, Henriet, S.S.V. (Stefanie S.V.), Jonge, M.I. (Marien) de, Kuipers, S. (Saskia), Langereis, J.D. (Jeroen), Weemaes, C.M.R. (Corry)   +6 more
core   +1 more source

Raising awareness of bronchiectasis in primary care:overview of diagnosis and management strategies in adults [PDF]

, 2017
Bronchiectasis is a chronic lung disease characterised by recurrent infection, inflammation, persistent cough and sputum production. The disease is increasing in prevalence, requiring a greater awareness of the disease across primary and secondary care ...
AB Chang, AD Saleh, AE Seitz, AK Gupta, AP Santos dos, AR McCullough, AT Hill, B Mao, BA Bruggen-Bogaarts van der, C Donatelli, CM Gould, CS Thompson, D Coutinho, D Weycker, E Abo-Salem, EM Glauser, F Paganin, H Green, I Honoré, I Papanikolaou, IK Park, IO Rosas, IS Patel, J Angrill, J Cooke, J Twiss, JA Pryor, JD Chalmers, JD Chalmers, JD Chalmers, JD Chalmers, JD Chalmers, JK Quint, JM Reich, JW Yang, K Grimwood, KA Lavery, LC Fan, LK Lewis, M Baque-Juston, M Bisht, M Martínez García, ME Boleken, MM Tunney, MM Wilczynska, MP Murray, MR Loebinger, MÁ Martínez-García, P Akuthota, P Bedi, PJ Cole, PT King, Q Wu, R Athanazio, RD Kim, RD Turner, S Aliberti, S Finch, S Lonni, S Mayor, S Sethi, S Xie, SA Collins, SJ Fowler, SP Bhatt, TF Barlam, WJ Guan, Y Ni, YH Gao, ZL Shi   +69 more
core   +3 more sources

Late infections after high‐dose therapy and autologous stem cell transplantation for lymphoma: A Danish population‐based study

British Journal of Haematology, Volume 207, Issue 3, Page 920-928, September 2025.
Summary Infectious complications after high‐dose therapy and autologous stem cell transplantation (HDT‐ASCT) for lymphoma are the leading cause of late non‐relapse mortality. Characterizing the risk of infectious complications over time is important for rational follow‐up and because alternatives to HDT‐ASCT exist for some patients.
Freja Tang Severinsen, Mikkel Runason Simonsen, Eva Futtrup Maksten, Lasse Hjort Jakobsen, Rasmus Kuhr Jensen, Kirstine Kobberøe Søgaard, Paw Jensen, Peter de Nully Brown, Judit Mészáros Jørgensen, Thomas Stauffer Larsen, Christian Bjørn Poulsen, Tarec Christoffer El‐Galaly   +11 more
wiley   +1 more source

Audit of immunoglobulin monitoring and hypogammaglobulinaemia after B cell targeted therapy in a paediatric cohort in a high immune disease prevalence Region

Clinical Medicine
Introduction: Secondary hypogammaglobulinaemia or antibody deficiency (SAD) is an under-recognised complication of B cell-targeted therapies (BCTTs) in both autoimmune diseases (AIDs) and haematological malignancy.
Khadija Karim, Omar Mostafa, Alaa Samarh, Sharon Bout-Tabaku, Buthaina Al-Adba, Ahmad Kaddourah, Abubakr Imam, Ibrahim Shatat, Bajes Hamad, Mahmoud Fawzi, Ruba Benini, Ayman Saleh, Tayseer Yousif, Areeg Ahmed, Yasmin El Bsat, Bernice Lo, Mohammed Yousuf Karim   +16 more
doaj   +1 more source

Adherence to guidelines across different specialties to prevent infections in patients undergoing immunosuppressive therapies

BMC Infectious Diseases, 2020
Background Substantial numbers of patients are now receiving either immunosuppressive therapies or chemotherapy. There are significant risks in such patients of developing opportunistic infections or re-activation of latent infections, with higher ...
David R. Chadwick, Laila Sayeed, Matthew Rose, Emily Budd, Mo Mohammed, Sarah Harrison, Jaskiran Azad, Jamie Maddox   +7 more
doaj   +1 more source

Consistent ex vivo cell proliferation during manufacturing predicts favourable outcomes post‐CAR‐T‐cell therapy

British Journal of Haematology, Volume 207, Issue 3, Page 1002-1010, September 2025.
Efficacy of chimeric antigen receptor (CAR) T‐cell therapy depends not only on tumour traits but also on the potency of CAR‐T cells. In clinical practice, the degrees of cell proliferation during CAR‐T‐cell manufacturing vary significantly among individual cases.
Tomoyasu Jo, Yasuyuki Arai, Tomoshige Shimizu, Toshio Kitawaki, Takashi Sakamoto, Chisaki Mizumoto, Junya Kanda, Momoko Nishikori, Kohei Yamashita, Miki Nagao, Akifumi Takaori‐Kondo   +10 more
wiley   +1 more source