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European Journal of Internal Medicine, 2014
Although secondary hypogammaglobulinemia is more frequent than primary hypogammaglobulinemia, its etiology and management are poorly described, particularly for mild hypogammaglobulinemia.This retrospective observational study included all adult patients with a gammaglobulin level
Mathieu Blot +2 more
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Although secondary hypogammaglobulinemia is more frequent than primary hypogammaglobulinemia, its etiology and management are poorly described, particularly for mild hypogammaglobulinemia.This retrospective observational study included all adult patients with a gammaglobulin level
Mathieu Blot +2 more
exaly +3 more sources
Heterogeneity of hypogammaglobulinemia
American Journal of Hematology, 1980AbstractIn 1952, Ogden Bruton described the first patient with recurrent infections and hypogammaglobulinemia [1]. For many years thereafter, hypogammaglobulinemia (or agammaglobulinemia) was believed to result from a deficiency (or absence) of the antibody‐producing cells, or “B” cell line of the lymphoid system.
M E Miller
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The Genetics of Hypogammaglobulinemia
Current Allergy and Asthma Reports, 2004Etiologies for human hypogammaglobulinemias are diverse and include genetic and nongenetic causes. Although recent reviews focus on the complex genetics of common variable immunodeficiency, in this review, we survey different causes of hypogammaglobulinemias and discuss possible mechanisms.
Grimbacher, Bodo +2 more
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Hypogammaglobulinemia and steatorrhea
The American Journal of Digestive Diseases, 19651. A patient with acquired idiopathic hypogammaglobulinemia and steatorrhea is described. Jejunal and ileal biopsies were histologically normal.
C F, McCarthy, W I, Austad, A E, Read
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DIAGNOSIS OF HYPOGAMMAGLOBULINEMIA
JAMA, 1962Prompt, accurate diagnosis of gamma globulin deficiency as a cause of unusual susceptibility to infection is extremely important for several reasons: first, replacement therapy with pooled normal gamma globulin is effective in the prevention of serious infections if initiated before structural damage has occurred; second, supplies of gamma globulin ...
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Pediatrics, 1960
An unusual patient, characterized by recurrent infections, hepatosplenomegaly, low levels of gamma-globulin in the serum (400 mg/100 ml) and lymphocytosis, is described. The patient had pneumonia due to Nocardia asteroides followed by chronic Salmonella newport infection of 16 months' duration, kept in check by continuous antibiotic ...
Thomas F. Dolan +2 more
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An unusual patient, characterized by recurrent infections, hepatosplenomegaly, low levels of gamma-globulin in the serum (400 mg/100 ml) and lymphocytosis, is described. The patient had pneumonia due to Nocardia asteroides followed by chronic Salmonella newport infection of 16 months' duration, kept in check by continuous antibiotic ...
Thomas F. Dolan +2 more
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Hypogammaglobulinemia and Pernicious Anemia
Southern Medical Journal, 1987We have described two patients with pernicious anemia in whom incidental hypogammaglobulinemia was discovered. According to our review of 41 cases of this association reported in the literature, our patients are similar to those previously reported in their young age, the evidence for antral involvement with the atrophic gastritis, and the absence in ...
P E, Wright, D A, Sears
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Primary Hypogammaglobulinemia and Malabsorption
Annals of Internal Medicine, 1971Abstract Intestinal absorption was investigated in six patients with a diagnosis of primary hypogammaglobulinemia. Malabsorption was found in four patients.
W S, Hughes +3 more
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Hypogammaglobulinemia With Sarcoidlike Granulomas
Archives of Pediatrics & Adolescent Medicine, 1983A 12-year-old girl had sarcoidlike syndrome and hypogammaglobulinemia. Pancytopenia and hepatosplenomegaly were noted at age 4 years. Histopathologic study showed typical sarcoidlike granulomas. Chronic lung disease, along with recurrent infections, developed.
R, Friedman +4 more
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Hypogammaglobulinemia and rheumatic disease
Seminars in Arthritis and Rheumatism, 1993Primary hypogammaglobulinemia describes a heterogeneous group of immunoglobulin disorders mainly composed of X-linked agammaglobulinemia, common variable immunodeficiency, and selective immunoglobulin (Ig) A deficiency. The most serious problems are related to recurrent infections with high-grade encapsulated bacteria.
A H, Lee, A I, Levinson, H R, Schumacher
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