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Partial restoration of counterregulatory circulating glucagon by dapagliflozin and low-dose glibenclamide in men with type 1 diabetes: in vitro studies and randomised clinical crossover trial. [PDF]
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Hyperinsulinaemic hypoglycaemia
Archives of Disease in Childhood, 2009Hyperinsulinaemic hypoglycaemia (HH) occurs as a consequence of unregulated insulin secretion from pancreatic beta cells. In the newborn period it is the most common cause of severe and persistent hypoglycaemia. As HH is a major risk factor for brain injury and subsequent neurodevelopment handicap, the identification, rapid diagnosis and prompt ...
R R, Kapoor +5 more
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Journal of Mental Science, 1959
For some years now it has been recognized that the symptoms induced by hypoglycaemia may resemble narcolepsy. Cases of islet-celled pancreatic adenomas simulating narcolepsy have been described by Harris (7), Delay (4) and Wyke (18). The resemblance may be a superficial one, however, and Wyke observed in his case during a “sleepy attack” that “the EEG ...
R A, SCHNEIDER, C M, SMITH
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For some years now it has been recognized that the symptoms induced by hypoglycaemia may resemble narcolepsy. Cases of islet-celled pancreatic adenomas simulating narcolepsy have been described by Harris (7), Delay (4) and Wyke (18). The resemblance may be a superficial one, however, and Wyke observed in his case during a “sleepy attack” that “the EEG ...
R A, SCHNEIDER, C M, SMITH
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2020
In health hypoglycaemia is rare and occurs only in circumstances like extreme sports. Hypoglycaemia in type 1 Diabetes (T1D) and advanced type 2 Diabetes (T2D) are the result of interplay between absolute or relative insulin access and defective glucose counterregulation.
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In health hypoglycaemia is rare and occurs only in circumstances like extreme sports. Hypoglycaemia in type 1 Diabetes (T1D) and advanced type 2 Diabetes (T2D) are the result of interplay between absolute or relative insulin access and defective glucose counterregulation.
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Hypoglycaemia in Type 2 diabetes
Diabetic Medicine, 2008 The primary cause of hypoglycaemia in Type 2 diabetes is diabetes medication-in particular, those which raise insulin levels independently of blood glucose, such as sulphonylureas (SUs) and exogenous insulin.
Stephanie A Amiel
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Best Practice & Research Clinical Endocrinology & Metabolism, 1999
Hypoglycaemia is a major factor preventing insulin-treated patients from achieving normoglycaemia. This reflects the inadequacy of current insulin treatment, which causes high insulin concentrations in the post-absorptive period. Physiological defences to hypoglycaemia include autonomic activation, which limits the fall in glucose level and causes ...
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Hypoglycaemia is a major factor preventing insulin-treated patients from achieving normoglycaemia. This reflects the inadequacy of current insulin treatment, which causes high insulin concentrations in the post-absorptive period. Physiological defences to hypoglycaemia include autonomic activation, which limits the fall in glucose level and causes ...
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1994
Hypoglycaemia is defined as a blood glucose concentration below 3.0 mmol/litre, which is clinically important because of its effect on brain function. Much the commonest cause is excessive (in relation to intake of food and drink) administration of insulin or sulphonylurea drugs to patients known to have diabetes, but there are many rarer causes ...
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Hypoglycaemia is defined as a blood glucose concentration below 3.0 mmol/litre, which is clinically important because of its effect on brain function. Much the commonest cause is excessive (in relation to intake of food and drink) administration of insulin or sulphonylurea drugs to patients known to have diabetes, but there are many rarer causes ...
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Medicine, 2002
Despite the advent of improved insulins, blood glucose monitoring and greater understanding of the pathophysiology, hypoglycaemia continues to be the main factor preventing insulin treated individuals with diabetes from reaching and maintaining glucose targets necessary to prevent long-term complications. The critical dependence of the CNS on a regular
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Despite the advent of improved insulins, blood glucose monitoring and greater understanding of the pathophysiology, hypoglycaemia continues to be the main factor preventing insulin treated individuals with diabetes from reaching and maintaining glucose targets necessary to prevent long-term complications. The critical dependence of the CNS on a regular
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Baillière's Clinical Endocrinology and Metabolism, 1993
Hypoglycaemia is a relatively common cause for referral of patients to the accident and emergency departments of hospitals but most of it is iatrogenic. Occasionally, however, hypoglycaemia is due to any one of up to a hundred different disorders. In some, hypoglycaemia is the cause of intermittent neuroglycopenic symptoms that lead to their referral ...
V, Marks, J D, Teale
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Hypoglycaemia is a relatively common cause for referral of patients to the accident and emergency departments of hospitals but most of it is iatrogenic. Occasionally, however, hypoglycaemia is due to any one of up to a hundred different disorders. In some, hypoglycaemia is the cause of intermittent neuroglycopenic symptoms that lead to their referral ...
V, Marks, J D, Teale
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Journal of Forensic and Legal Medicine, 2007
A case of a detained person (DP) suffering from insulin-dependent diabetes, who subsequently used the disorder in his defence as a reason to claim automatism, is discussed. The legal and medical history of automatism is outlined along with the present day situation.
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A case of a detained person (DP) suffering from insulin-dependent diabetes, who subsequently used the disorder in his defence as a reason to claim automatism, is discussed. The legal and medical history of automatism is outlined along with the present day situation.
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