Results 131 to 140 of about 47,945 (166)
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Clinical Pharmacology & Therapeutics, 1962
The chance observation by Janbon in 1942 that p‐aminosulfonamide caused hypoglycemia initiated an extensive search for oral hypoglycemic agents for diabetes mellitus. In the 20 years since Janbon's discovery, many agents have been studied. Some of them have been discarded after preliminary animal studies, whereas others have undergone clinical ...
James C. Barrett, Buris R Boshell
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The chance observation by Janbon in 1942 that p‐aminosulfonamide caused hypoglycemia initiated an extensive search for oral hypoglycemic agents for diabetes mellitus. In the 20 years since Janbon's discovery, many agents have been studied. Some of them have been discarded after preliminary animal studies, whereas others have undergone clinical ...
James C. Barrett, Buris R Boshell
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Oral Hypoglycemic Agent Update
Medical Clinics of North America, 1978The treatment of diabetes is still a problem more than a half-century after the discovery of insulin. Patients are now living significantly longer but until the development of oral hypoglycemic agents, the only direct treatment modalities were exercise, diet, and insulin.
Leo P. Krall, Valdo A. Chabot
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Pediatrics, 1969
I noted with interest the article by Drs. Adam and Schwartz, "Should Oral Hypoglycemic Agents Be Used in Pediatric and Pregnant Patients?" (Pediatrics, 42:819, 1968). In regard to juvenile diabetics, his conclusions were an echo of what usually appears in the ped iatric literature, namely, these drugs have no place in the management of any pediatric ...
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I noted with interest the article by Drs. Adam and Schwartz, "Should Oral Hypoglycemic Agents Be Used in Pediatric and Pregnant Patients?" (Pediatrics, 42:819, 1968). In regard to juvenile diabetics, his conclusions were an echo of what usually appears in the ped iatric literature, namely, these drugs have no place in the management of any pediatric ...
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PRACTICAL USE OF HYPOGLYCEMIC AGENTS
Journal of the American Medical Association, 1960The cornerstone of all proper treatment of diabetes mellitus is a diet adjusted to the patient's weight, height, sex, physical activity, and diabetic status. Regular insulin is essential in treating acidosis and coma; the lente insulins and other derived insulins can be used advantageously in combination with it.
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METAHEXIMIDE AS A HYPOGLYCEMIC AGENT
Journal of the American Medical Association, 1960To the Editor:— The abstract of the report "Further Experience with Oral Therapy in Diabetes" (J. A. M. A.172:876 [Feb. 20] 1960) merits comment in view of the statement in it that "these findings suggest that metaheximide is a well-tolerated hypoglycemic agent." In a form letter for mailing list distribution in June, 1959, W. F.
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Ciglitazone, a New Hypoglycemic Agent
Nephron, 1986Kidneys of treated and control C57BL/KsJ-db/db mice were analyzed by semiquantitative light microscopy to determine the effects of ciglitazone on the deposition of fluorescein-conjugated IgM and IgG ...
Barbara J. Gilchrist +7 more
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Insulins and oral hypoglycemic agents in pregnancy
The Journal of Maternal-Fetal & Neonatal Medicine, 2006Numerous studies have established a direct relationship between maternal levels of glycemic control and neonatal outcomes for pregnancies complicated by diabetes. The past several years have seen the addition of insulin analogues as well as many new oral agents to the pharmacological armamentarium available to treat diabetes.
E. Albert Reece, Carol J. Homko
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Journal of the American Medical Association, 1959
To the Editor:— Since the advent of the oral hypoglycemics the physician has been lulled into a sense of security that he will not have to be concerned about potentially dangerous reactions, despite one documented report of a fatal hypoglycemic reaction (McKendry, Canad. M. A. J. 76 :572-573 [April 1] 1957).
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To the Editor:— Since the advent of the oral hypoglycemics the physician has been lulled into a sense of security that he will not have to be concerned about potentially dangerous reactions, despite one documented report of a fatal hypoglycemic reaction (McKendry, Canad. M. A. J. 76 :572-573 [April 1] 1957).
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The Use of Oral Hypoglycemic Agents
Hospital Practice, 1979The sulfonylureas are primarily indicated for nonketotic patients with adult-onset diabetes that cannot be controlled by diet alone. When properly prescribed for appropriate Patients, they are no more likely than diet or insulin to cause cardiac complications.
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Suicidal overdoses with hypoglycemic agents
Journal of the American College of Emergency Physicians, 1979Suicide attempts using hypoglycemic agents are uncommon but are associated with a high level of morbidity and mortality. Their recognition is sometimes difficult and the duration of hypoglycemic effect is often prolonged. Two cases that illustrate the difficulties encountered in recognition and therapy are described.
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