BioMed Research International, 2021 Diabetes mellitus termed as metabolic disorder is a collection of interlinked diseases and mainly body's inability to manage glucose level which leads to cardiovascular diseases, renal failure, neurological disorders, and many others.
Rawaba Arif +6 more
semanticscholar +1 more source
Pharmacogenetics of hypoglycemic agents
Сахарный диабет, 2015 Despite the increase in the number of hypoglycemic agents, 35%–40% of patients with diabetes are unable to achieve adequate glycemic control. One of the reasons is the genetic heterogeneity of diabetes mellitus, requiring different treatment approaches ...
Irina Vladimirovna Kononenko +3 more
doaj +1 more source
Minimizing hypoglycemia while maintaining glycemic control in diabetes [PDF]
, 2008 In the accompanying Perspective, Cryer identifies a number of different areas where therapeutic interventions have the potential to reduce hypoglycemia without compromising glycemic control.
Heller, S.
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Hypoglycemic Coma in a Hemodialysis Patient Receiving Blood Glucose-Lowering Therapy With the Single Agent Teneligliptin [PDF]
Clinical Medicine Insights: Case Reports, 2018 Blood glucose management in patients undergoing dialysis is clinically challenging. In this population, most conventional oral hypoglycemic agents are contraindicated, especially from the perspective of pharmacokinetics. Dipeptidyl peptidase-4 inhibitors
Takumi Minezumi +5 more
openalex +2 more sources
Comparison of glycemic excursion in patients with new onset type 2 diabetes mellitus before and after treatment with repaglinide [PDF]
, 2013 Due to industrialization and sedentary life, incidence of type 2 diabetes (DM2) is increasing seriously. Repaglinide is a glucose reducing agent that predominantly reduces post-prandial glucose.
Bonakdaran, S. +4 more
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Design, synthesis and pharmacological evaluation of novel vanadium-containing complexes as antidiabetic agents. [PDF]
PLoS ONE, 2014 Based on the data about structure and antidiabetic activity of twenty seven vanadium and zinc coordination complexes collected from literature we developed QSAR models using the GUSAR program.
Elena V Fedorova +5 more
doaj +1 more source
Impact of hypoglycemia on patients with type 2 diabetes mellitus and their quality of life, work productivity, and medication adherence. [PDF]
, 2014 BackgroundThe purpose of this study was to determine the characteristics of adults with type 2 diabetes mellitus (T2DM) that correlate with greater risk of hypoglycemia and determine the impact of hypoglycemia on health-related quality of life, work ...
Annunziata, Kathy +4 more
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Frontiers in Pharmacology, 2018 Spices possess tremendous therapeutic potential including hypoglycemic action, attributed to their bioactive ingredients. However, there is no study that critically reviewed the hypoglycemic potency, safety and the bioavailability of the spice-derived ...
Aminu Mohammed +2 more
doaj +1 more source
Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia [PDF]
, 2011 OBJECTIVE: Lactic acidosis has been associated with use of metformin. Hypoglycemia is a major concern using sulfonylureas. The aim of this study was to compare the risk of lactic acidosis and hypoglycemia among patients with type 2 diabetes using oral ...
Bodmer, Michael +4 more
core +2 more sources
New hypoglycemic agents and the kidney: what do the major trials tell us? [PDF]
F1000Res, 2018 Brendan Smyth, Vlado Perkovic
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