Background Adolescents with DMD treated with chronic high dose GC therapy typically have profound pubertal delay. Testosterone, the main circulating androgen in men, promotes virilisation and growth with associated accrual of fat-free muscle mass and ...
C. L. Wood+7 more
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Recombinant follitropin alfa/lutropin alfa in fertility treatment
Ahmed Gibreel1, Siladitya Bhattacharya21School of Medicine and Dentistry, University of Aberdeen; 2Aberdeen Maternity Hospital, Aberdeen, UKAbstract: Recombinant human follicle stimulating hormone (rFSH) and luteinizing hormone (LH), also known as ...
Ahmed Gibreel, Siladitya Bhattacharya
doaj
Background Immune‐checkpoint inhibitors have been shown to improve survival in melanoma patients, but can also trigger immune‐related endocrinopathies, especially hypophysitis and thyroid dysfunction.
Eva Kassi+12 more
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Glucagon like pepetide-1 agonist in a patient with prader-willi syndrome: a Sri Lankan experience
BackgroundPrader-Willi Syndrome (PWS) is a genetic disease characterized by morbid obesity and hyperphagia. Although the exact pathophysiological basis of obesity and hyperphagia remains unclear it is thought to be mainly due to hypothalamic dysfunction.
Maulee Hiromi Arambewela+1 more
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Haemoglobinopathies care and cure: Have we reached the end?
Recent years have seen accelerating advances in the treatment, monitoring and potential cures for haemoglobin disorders, as the interaction between basic science, pharmaceutical research, and practical medicine intensifies.
John Porter
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GONADOTROPHIN RESPONSES TO GnRH PULSES IN HYPOGONADOTROPHIC HYPOGONADISM: LH RESPONSIVENESS IS MAINTAINED IN THE PRESENCE OF LUTEAL PHASE CONCENTRATIONS OF OESTROGEN AND PROGESTERONE [PDF]
Todd B. Nippoldt+4 more
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NOCTURNAL PULSATILE LH SECRETION IN PREPUBERTY AND HYPOGONADOTROPHIC HYPOGONADISM ASSESSED BY A HIGHLY SENSITIVE IMMUNORADIOMETRIC ASSAY (IRMA) [PDF]
F.C.W. Wu+3 more
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Testicular dysfunction in men with primary hypothyroidism; reversal of hypogonadotrophic hypogonadism with replacement thyroxine [PDF]
P Donnelly, Chris White
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Kallmann syndrome and deafness: an uncommon combination: A case report and a literature review
Background: Kallmann syndrome (Kal S) is an isolated form of hypogonadotrophic hypogonadism in combination with a defect in smell sensation. Depending on the genetic form of the disease, a number of non-reproductive, non-olfactory abnormalities may also ...
Nader Salama
doaj
Hypogonadotrophic hypogonadism, short stature, cerebellar ataxia, rod-cone retinal dystrophy, and hypersegmented neutrophils: a novel disorder or a new variant of Boucher-Neuhauser syndrome? [PDF]
A-K Jbour
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