A novel GNRHR gene mutation causing congenital hypogonadotrophic hypogonadism in a Brazilian kindred
Journal of neuroendocrinology, 2018Congenital hypogonadotrophic hypogonadism (CHH) is a challenging inherited endocrine disorder characterised by absent or incomplete pubertal development and infertility as a result of the low action/secretion of the hypothalamic gonadotrophin‐releasing ...
S. R. Correa-Silva+10 more
semanticscholar +1 more source
Hypogonadotrophic Hypogonadism Associated with Anosmia in the Female
Australian and New Zealand Journal of Obstetrics and Gynaecology, 1974Summary: Three women with hypogonadotrophic hypogonadism associated with anosmia were subjected to ovarian stimulation with human gonadotrophins. The first responded normally to conventional dosage of human pituitary gonadotrophins (HPG). The second, known to have primordial follicles in the ovary, failed to respond to massive doses of HPG. The third,
J. D. Martin+3 more
openaire +2 more sources
Pituitary imaging findings in male patients with hypogonadotrophic hypogonadism [PDF]
Data on pituitary imaging in adult male patients presenting with hypogonadotrophic hypogonadism (HH) and no known pituitary disease are scarce.To assess the usefulness of pituitary imaging in the evaluation of men presenting with HH after excluding known pituitary disorders and hyperprolactinemia.A historical prospective cohort of males with HH.Men who
Dania Hirsch+12 more
openaire +2 more sources
Management of Hypogonadotrophic-Hypogonadism
2014Hypogonadotrophic-hypogonadism (hypothalamic-pituitary failure -WHO Group I), is a situation in which gonadotrophin concentrations are so low as to be completely unable to stimulate follicle development and oestrogen production from the ovaries. Anovulation, amenorrhea and hypo-oestrogenism are the consequences.
openaire +2 more sources
Ejaculatory failure and hypogonadotrophic hypogonadism caused by haemochromatosis
BJU International, 1999[No abstract available ...
Stopforth H.B.+3 more
openaire +4 more sources
HYPOGONADOTROPHIC HYPOGONADISM - A CASE REPORT
Journal of the ASEAN Federation of Endocrine Societies, 2019INTRODUCTIONHypogonadotrophic hypogonadism (HH) is a rare condition usually affecting the males. The estimated incidence is 1-10:100000 live births. Common presentations are infertility and delayed puberty.
Qing Yu T, Song Hai L
semanticscholar +1 more source
PULSATILE ADMINISTRATION OF GnRH FOR THE TREATMENT OF HYPOGONADOTROPHIC HYPOGONADISM
Clinical Endocrinology, 1984SUMMARYFourteen patients, aged 22‐35 years, complaining of infertility and failing to ovulate on clomiphene, were treated with GnRH administered in pulses at 90 min intervals. Four patients received a total of eight courses of GnRH given subcutaneously and 13 were given a total of 20 months of treatment with GnRH given intravenously.
S. S. Lynch+4 more
openaire +3 more sources
The fine structure of the immature human testis in hypogonadotrophic hypogonadism [PDF]
The ultrastructural appearance of the immature human testis was studied in biopsies from 3 patients with hypogonadotrophic hypogonadism. The immature Sertoli cells exhibit an unusual gradation in nucleolar structure and differ from the adult Sertoli cell in the amount and distribution of lipid, agranular and granular endoplasmic reticulum.
openaire +2 more sources
Anorexia nervosa: Hypogonadotrophic Hypogonadism and Bone Mineral Density
Hormone Research in Paediatrics, 2002Anorexia nervosa is a chronic illness that involves a reduction in caloric intake, loss of weight and amenorrhoea, either primary or secondary. In addition to prolonged amenorrhoea, osteopenia and osteoporosis are the most frequent complications. Patients exhibit an alteration in the hypothalamic-pituitary-gonadal axis, which is responsible for the ...
M T Muñoz, Jesús Argente
openaire +3 more sources
Clinical Evaluation in Isolated Hypogonadotrophic Hypogonadism (Kallmann Syndrome)
Journal of Pediatric Endocrinology and Metabolism, 1998To describe the clinical features, laboratory investigation and treatment of Kallmann syndrome.A retrospective study of patients treated in the Endocrine Clinic of the Royal Children's Hospital and St Vincent's Hospital, Melbourne, between 1984 and 1996.Eleven males and 5 females with Kallmann syndrome are described.
G L Warne, P Dissaneevate, M R Zacharin
openaire +3 more sources