Gonadotrophin therapy in combination with ICSI in men with hypogonadotrophic hypogonadism
Reproductive BioMedicine Online, 2007 The aim of this study was to evaluate the impact of gonadotrophin therapy in combination with intracytoplasmic sperm injection (ICSI) in men with hypogonadotrophic hypogonadism (HH). Twenty-five azoospermic men were diagnosed with HH due to low FSH, LH and total testosterone concentrations. These patients were treated with human chorionic gonadotrophin
Emre Bakırcıoğlu +4 more
openalex +4 more sources
Late-onset X-linked adrenal hypoplasia (DAX-1, NR0B1): two new adult-onset cases from a single center [PDF]
, 2017 PURPOSE: DAX-1 (NR0B1) is an orphan nuclear receptor, which plays a critical role in development and regulation of the adrenal gland and hypothalamo-pituitary-gonadal axis.
Achermann, JC +6 more
core +1 more source
Indian Journal of Endocrinology and Metabolism, 2012 We present here a case of 17-year-old boy from Kolkata presenting with obesity, bilateral gynecomastia, mental retardation, and hypogonadotrophic hypogonadism. The patient weighed 70 kg and was of 153 cm height. Facial asymmetry (unilateral facial palsy),
Semanti Chakraborty, Jayanta Chakraborty
doaj +1 more source
Comprehensive Review on Kisspeptin and Its Role in Reproductive Disorders [PDF]
Endocrinology and Metabolism, 2015 Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis. It is known that kisspeptin, acting centrally via the kisspeptin receptor, stimulates secretion of gonadotrophin releasing hormone (GnRH). Loss of kisspeptin signaling
Holly Clarke +2 more
doaj +1 more source
The ability of lumbar spine DXA and phalanx QUS to detect previous fractures in young thalassemic patients with hypogonadism, hypothyroidism, diabetes, and hepatitis-B: A 2-year subgroup analysis from the Taranto Area of Apulia Region. [PDF]
, 2013 BACKGROUND: Osteoporosis is a leading cause of morbidity in patients affected by β-thalassemia major or intermediate; we aimed to assess the association between demineralization observed in young thalassemic patients. METHODS: A total of 88 patients with
Agnello, Nadia +14 more
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Hypogonadotrophic hypogonadism in type 2 diabetes
The Aging Male, 2008 Recent work shows a high prevalence of low testosterone and inappropriately low luteinizing hormone (LH) and follicle stimulating hormone (FSH) concentrations in type 2 diabetes. This syndrome of hypogonadotrophic hypogonadism (HH) is associated with obesity in patients with type 2 diabetes. However, the duration of diabetes or HbA1c are not related to
Vishal Bhatia +4 more
openaire +3 more sources
, 2023 Clinical Endocrinology, Volume 98, Issue 3, Page 454-456, March 2023.
Sophie Howarth +2 more
wiley +1 more source
Mutational analysis of DAX1 in patients with hypogonadotropic hypogonadism or pubertal delay [PDF]
, 1999 Although delayed puberty is relatively common and often familial, its molecular and pathophysiologic basis is poorly understood. In contrast, the molecular mechanisms underlying some forms of hypogonadotropic hypogonadism (HH) are clearer, following the ...
Achermann, JC +12 more
core +1 more source
Granular cell tumour of the neurohypophysis: an unusual cause of hypopituitarism
Endocrinology, Diabetes & Metabolism Case Reports, 2018 Granular cell tumours (GCT) are rare, slow-growing, benign neoplasms that are usually located in the head and neck. They are more frequent in the female gender and typically have an asymptomatic clinical course, being diagnosed only at autopsy ...
Carlos Tavares Bello +4 more
doaj +1 more source
Ataxia with oculomotor apraxia type 2: clinical, biological and genotype/phenotype correlation study of a cohort of 90 patients [PDF]
, 2009 Ataxia with oculomotor apraxia type 2 (AOA2) is an autosomal recessive disease due to mutations in the senataxin gene, causing progressive cerebellar ataxia with peripheral neuropathy, cerebellar atrophy, occasional oculomotor apraxia and elevated alpha ...
Ali-Pacha, L +34 more
core +1 more source