Results 51 to 60 of about 23,463 (198)
The Bidirectional Association Between MASLD and Male Hypogonadism: An Updated Meta‐Analysis
Andrology, EarlyView.ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) and male hypogonadism are increasingly prevalent, metabolically interrelated conditions. Testosterone (T) deficiency has been implicated in hepatic lipid dysregulation, insulin resistance, and visceral adiposity, whereas MASLD may impair the hypothalamic–pituitary ...
Giorgia Spaggiari +9 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Drugs used for diabetes and obesity increasingly shape male sexual and reproductive counseling, but clinical studies, trial registrations, regulatory labels, and patents answer different questions. Objectives The objective is to map these sources and define what each can support when counseling men receiving metabolic drugs ...
Marek Broul +3 more
wiley +1 more source
Narcolepsy, depression, and severe flushing in an obese man
Clinical Case Reports, 2020 Hypogonadism as a cause of depression, daytime sleepiness, and flushing is often missed in young males. Our case report highlights the importance of screening for hypogonadotropic hypogonadism and its treatment in symptomatic men with severe obesity ...
Fatimo Biobaku +4 more
doaj +1 more source
Patient with adrenal insufficiency due to a de novo mutation in the NR0B1 gene
Advances in Laboratory Medicine, 2023 Congenital X-linked adrenal hypoplasia is a rare disease with a known genetic basis characterized by adrenal insufficiency, hypogonadotropic hypogonadism, and a wide variety of clinical manifestations.
Bravo Nieto Daniel +8 more
doaj +1 more source
The Need for a Global Registry for Charting the Natural History of Klinefelter Syndrome
Andrology, EarlyView.ABSTRACT Background Although Klinefelter Syndrome (KS) represents the most common sex chromosome aneuploidy, several gaps in knowledge persist regarding optimal management of individuals with this condition. Individuals with KS can have a diverse phenotype including endocrine, neurodevelopmental, and cardiovascular manifestations.
Malika Alimussina +13 more
wiley +1 more source
Hypogonadism in Cisgender Men Living With HIV: Prevalence, Clinical and Metabolic Features
Andrology, EarlyView.ABSTRACT Background Hypogonadism is frequently observed in men living with human immunodeficiency virus (HIV), although its prevalence, etiology, and predictors remain incompletely understood. Objective To evaluate the prevalence of hypogonadism and its association with metabolic factors in men living with HIV (MLWH), on stable antiretroviral therapy ...
Felipe Augusto Azevedo Leao +8 more
wiley +1 more source
Frontiers in Endocrinology, 2019 RNF216, encoding an E3 ubiquitin ligase, has been identified as a causative gene for Gordon Holmes syndrome, characterized by ataxia, dementia, and hypogonadotropic hypogonadism.
Fangfang Li +12 more
doaj +1 more source
Journal of Family Medicine and Primary Care, 2020 Context: Primary Amenorrhea is worrisome for the adolescent as well as their guardian. It is essential to be able to identify the underlying pathology and initiate appropriate management strategies, well in time.
Japleen Kaur +5 more
doaj +1 more source
Clinical Genetics, EarlyView.These two siblings carrying the homozygous FIBP c.412‐3_415dupCAGTTTG variant, previously identified in several Turkish families, further delineate the clinical spectrum of TROFAS. Postaxial polydactyly and an upper lip vascular malformation, observed in Patient 2, have not previously been reported in association with this syndrome.
Federica Ruscitti +9 more
wiley +1 more source
Медицинский совет, 2018 Currently, testosterone drugs are used to treat hypogonadotropic hypogonadism, which allow men to get a good height and reach a stage of sexual development corresponding to their age.
Yu. L. Skorodok +3 more
doaj +1 more source