Results 71 to 80 of about 41,302 (312)

Clinical indicators to define etiology in patients with primary amenorrhea: Lessons from a decade of experience

open access: yesJournal of Family Medicine and Primary Care, 2020
Context: Primary Amenorrhea is worrisome for the adolescent as well as their guardian. It is essential to be able to identify the underlying pathology and initiate appropriate management strategies, well in time.
Japleen Kaur   +5 more
doaj   +1 more source

Clinical case seminar - Hypogonadotropic hypogonadism as a presenting feature of late-onset X-linked adrenal hypoplasia congenita [PDF]

open access: yes, 2002
Mutations in the orphan nuclear receptor DAX-1 cause X-linked adrenal hypoplasia congenita. Affected boys usually present with primary adrenal failure in early infancy or childhood.
Achermann, JC   +8 more
core  

Beyond hormone replacement: quality of life in women with congenital hypogonadotropic hypogonadism. [PDF]

open access: yes, 2017
Little is known about how women with isolated GnRH deficiency cope with their condition. This study aimed to examine the health and informational needs of women with congenital hypogonadotropic hypogonadism (CHH) and evaluate if their experiences differ ...
Dwyer, A.A.   +5 more
core   +1 more source

Modified cytoskeletal and extracellular matrix composition in the canine testis after long‐acting gonadotropin‐releasing hormone agonist deslorelin treatment

open access: yesAndrology, EarlyView.
Abstract Background Long‐acting gonadotropin‐releasing hormone (GnRH) agonists are commonly used for fertility control in male dogs. Their effect on testicular histomorphology has not been clarified. Objectives To elucidate the mechanisms underlying androgen withdrawal in response to long‐acting GnRH agonist deslorelin 4.7 mg treatment on testicular ...
Aykut Gram   +5 more
wiley   +1 more source

Hypogonadotropic Hypogonadism Associated with Hereditary Hemorrhagic Telengiectasia

open access: yesCase Reports in Endocrinology, 2013
A 65-year-old man was referred to our clinic for the rehabilitation of right hemiparesis caused by ischaemic stroke. Hypertension, postphlebitic syndrome of lower limbs, frequent nose bleeding, and anemia were present in his history; in his adolescence ...
Scarano Valentina   +6 more
doaj   +1 more source

RNF216 Regulates the Migration of Immortalized GnRH Neurons by Suppressing Beclin1-Mediated Autophagy

open access: yesFrontiers in Endocrinology, 2019
RNF216, encoding an E3 ubiquitin ligase, has been identified as a causative gene for Gordon Holmes syndrome, characterized by ataxia, dementia, and hypogonadotropic hypogonadism.
Fangfang Li   +12 more
doaj   +1 more source

Pubertal Assessment and Growth in Patients With Hemoglobinopathies: A Longitudinal Multicenter Study on the Association With Ferritin Levels

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Objectives Although Advancements in the Treatment of Hemoglobinopathies have Considerably Increased Life Expectancy, Hormonal and Pubertal Development Have Been Continuously Affected by Complications From Transfusion‐Related Iron Overload and Cytotoxic Therapies.
J. Dülberg   +20 more
wiley   +1 more source

The use of recombinant FSH in combination therapy in a young male with idiopathic hypogonadotropic hypogonadism

open access: yesМедицинский совет, 2018
Currently, testosterone drugs are used to treat hypogonadotropic hypogonadism, which allow men to get a good height and reach a stage of sexual development corresponding to their age.
Yu. L. Skorodok   +3 more
doaj   +1 more source

A perspective on diabetes-related hypogonadism

open access: yesCurrent Medicine Research and Practice, 2021
Testosterone deficiency leads to hypogonadism, which has shown a direct correlation with Type 2 diabetes mellitus. Hypogonadotropic hypogonadism is the major classification of hypogonadism, based on origin, which is related with diabetes.
Shikhar Tripathi   +3 more
doaj   +1 more source

Distinct expression patterns predict differential roles of the miRNA-binding proteins, Lin28 and Lin28b, in the mouse testis: studies during postnatal development and in a model of hypogonadotropic hypogonadism [PDF]

open access: yes, 2013
[Abstract] Lin28 (also termed Lin28a) and Lin28b are related RNA-binding proteins, involved in the control of microRNA synthesis, especially of the let-7 family, with putative functions in early (embryo) development. However, their roles during postnatal
Cordido, Fernando   +10 more
core   +2 more sources

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