Results 71 to 80 of about 30,173 (242)
Pharmacogenetics of follicle‐stimulating hormone action in the male
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani+7 more
wiley +1 more source
Syndrome of the Month: Bosma Arhinia Microphthalmia Syndrome
American Journal of Medical Genetics Part A, EarlyView.
Katherine J. K. Patterson+2 more
wiley +1 more source
Abstract Background Long‐acting gonadotropin‐releasing hormone (GnRH) agonists are commonly used for fertility control in male dogs. Their effect on testicular histomorphology has not been clarified. Objectives To elucidate the mechanisms underlying androgen withdrawal in response to long‐acting GnRH agonist deslorelin 4.7 mg treatment on testicular ...
Aykut Gram+5 more
wiley +1 more source
OBJECTIVE Isolated hypogonadotropic hypogonadism (IHH) is a rare disorder with pubertal delay, normal (normoosmic-IHH, nIHH) or defective sense of smell (Kallmann syndrome, KS).
M. Bonomi+29 more
semanticscholar +1 more source
Hypogonadotropic hypogonadism is a common finding in patients who are diagnosed with a prolactinoma. It can be accompanied by the presence of other pituitary hormone deficits, including secondary adrenal insufficiency and central hypothyroidism.
Lakshmi P Menon, Dinesh Edem
doaj +1 more source
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody+6 more
wiley +1 more source
Multiple metabolic and inflammatory mechanisms are considered the determinants of acquired functional isolated hypogonadotropic hypogonadism (IHH) in males, whereas classic IHH is a rare congenital condition with a strong genetic background.
B. Cangiano+8 more
semanticscholar +1 more source
Hypogonadotropic and Hypergonadotropic Hypogonadism
Male hypogonadism is a clinical syndrome that results from failure of the testis to produce physiological levels of testosterone and adequate spermatogenesis as a result of disruption of one or more levels of the hypothalamic-pituitary-testicular axis. Diagnosis of hypogonadism can be difficult given that the symptoms and signs are nonspecific and can ...
Ronald S. Swerdloff, Vijaya Surampudi
openaire +2 more sources
Hypogonadism in thalassemia major patients
Despite recent advances in iron chelation therapy, excess iron deposition in pituitary gonadotropic cells remains one of the major problems in thalassemic patients.
Sasima Srisukh+2 more
doaj +1 more source
ABSTRACT Introduction Worldwide, combined 17‐hydroxylase/17,20‐lyase deficiency (CYP17D) is a rare form of congenital adrenal hyperplasia, but it is the second most prevalent type in Brazil. An absence of sexual differentiation and hypergonadotropic hypogonadism arise from a reduction in the usual pattern of sex steroid formation in the adrenals and ...
Rafaela Fontenele+9 more
wiley +1 more source