Results 71 to 80 of about 30,173 (242)

Pharmacogenetics of follicle‐stimulating hormone action in the male

open access: yesAndrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani   +7 more
wiley   +1 more source

Syndrome of the Month: Bosma Arhinia Microphthalmia Syndrome

open access: yes
American Journal of Medical Genetics Part A, EarlyView.
Katherine J. K. Patterson   +2 more
wiley   +1 more source

Modified cytoskeletal and extracellular matrix composition in the canine testis after long‐acting gonadotropin‐releasing hormone agonist deslorelin treatment

open access: yesAndrology, EarlyView.
Abstract Background Long‐acting gonadotropin‐releasing hormone (GnRH) agonists are commonly used for fertility control in male dogs. Their effect on testicular histomorphology has not been clarified. Objectives To elucidate the mechanisms underlying androgen withdrawal in response to long‐acting GnRH agonist deslorelin 4.7 mg treatment on testicular ...
Aykut Gram   +5 more
wiley   +1 more source

Characteristics of a nationwide cohort of patients presenting with isolated hypogonadotropic hypogonadism (IHH).

open access: yesEuropean Journal of Endocrinology, 2018
OBJECTIVE Isolated hypogonadotropic hypogonadism (IHH) is a rare disorder with pubertal delay, normal (normoosmic-IHH, nIHH) or defective sense of smell (Kallmann syndrome, KS).
M. Bonomi   +29 more
semanticscholar   +1 more source

A case of giant prolactinoma and pituitary hemorrhage with the late recovery of pituitary function: A case report

open access: yesSAGE Open Medical Case Reports, 2023
Hypogonadotropic hypogonadism is a common finding in patients who are diagnosed with a prolactinoma. It can be accompanied by the presence of other pituitary hormone deficits, including secondary adrenal insufficiency and central hypothyroidism.
Lakshmi P Menon, Dinesh Edem
doaj   +1 more source

Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours

open access: yesAndrology, EarlyView.
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody   +6 more
wiley   +1 more source

Evidence for a Common Genetic Origin of Classic and Milder Adult-Onset Forms of Isolated Hypogonadotropic Hypogonadism

open access: yesJournal of Clinical Medicine, 2019
Multiple metabolic and inflammatory mechanisms are considered the determinants of acquired functional isolated hypogonadotropic hypogonadism (IHH) in males, whereas classic IHH is a rare congenital condition with a strong genetic background.
B. Cangiano   +8 more
semanticscholar   +1 more source

Hypogonadotropic and Hypergonadotropic Hypogonadism

open access: yes, 2017
Male hypogonadism is a clinical syndrome that results from failure of the testis to produce physiological levels of testosterone and adequate spermatogenesis as a result of disruption of one or more levels of the hypothalamic-pituitary-testicular axis. Diagnosis of hypogonadism can be difficult given that the symptoms and signs are nonspecific and can ...
Ronald S. Swerdloff, Vijaya Surampudi
openaire   +2 more sources

Hypogonadism in thalassemia major patients

open access: yesJournal of Clinical & Translational Endocrinology, 2016
Despite recent advances in iron chelation therapy, excess iron deposition in pituitary gonadotropic cells remains one of the major problems in thalassemic patients.
Sasima Srisukh   +2 more
doaj   +1 more source

Delayed Bone Maturation and Extended Growth Phase as Distinctive Features of 17α‐Hydroxylase/17,20‐Lyase Deficiency: A Retro‐Prospective Study of a Large Patient Cohort

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Introduction Worldwide, combined 17‐hydroxylase/17,20‐lyase deficiency (CYP17D) is a rare form of congenital adrenal hyperplasia, but it is the second most prevalent type in Brazil. An absence of sexual differentiation and hypergonadotropic hypogonadism arise from a reduction in the usual pattern of sex steroid formation in the adrenals and ...
Rafaela Fontenele   +9 more
wiley   +1 more source

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