Results 151 to 160 of about 713 (175)
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Adult-type hypolactasia and regulation of lactase expression
Biochimica et Biophysica Acta (BBA) - General Subjects, 2005A common genetically determined polymorphism in the human population leads to two distinct phenotypes in adults, lactase persistence and adult-type hypolactasia (lactase non-persistence). All healthy newborn children express high levels of lactase and are able to digest large quantities of lactose, the main carbohydrate in milk.
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Adult Hypolactasia, Milk Consumption, and Age-specific Fertility
American Journal of Epidemiology, 1994Beta-galactosidase (lactase) allows the digestion of lactose as its component sugars, galactose and glucose. Considerable variation exists worldwide in the prevalence of adults who lose the ability to digest lactose after infancy (hypolactasia) as well as in the amount of milk products they consume.
D W, Cramer, H, Xu, T, Sahi
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[Hypolactasia in Japanese Crohn's patients].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 199320 g lactose load test, BHT and LTT done simultaneously were examined in 32 Crohn's disease patients and 51 healthy volunteers. Hypolactasia frequency were examined. A rise in hydrogen concentration > 20 parts per million (ppm) above the base line during breath hydrogen test and maximum blood sugar rise during lactose tolerance test were considered to ...
M, Ogata, T, Yao
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Mosaic regulation of lactase in human adult-type hypolactasia
Gastroenterology, 1994We have previously shown that in the proximal-jejunum of hypolactasic humans, just a few villus enterocytes express lactase protein and activity. In the present study, we compared the distribution of lactase messenger RNA (mRNA), protein, and activity in villus enterocytes in tissues obtained from subjects with persistent high lactase activity and ...
MAIURI L +8 more
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Beneficial effects of oral tilactase on patients with hypolactasia
European Journal of Clinical Investigation, 2008ABSTRACTBackground A lactose‐free diet is commonly prescribed to subjects with hypolactasia. We tested the effectiveness of a single ingestion of tilactase (a β‐d‐galactosidase fromAspergillus oryzae) in adults with hypolactasia, previously assessed by lactose H2‐breath test.Materials and methods After measurement of orocecal transit time (OCTT, by ...
P Portincasa +5 more
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Hypolactasia and Crohn's disease: a myth.
The American journal of gastroenterology, 1990A retrospective analysis was made of jejunal biopsies performed on 62 patients with Crohn's disease for disaccharidase levels and routine histology. Thirteen patients with irritable bowel syndrome acted as a control group. Two patients with Crohn's disease had hypolactasia.
R H, Park, A, Duncan, R I, Russell
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Strip Test is Reliable in Common Prevalences of Hypolactasia
Scandinavian Journal of Gastroenterology, 1987The object of this study was to compare the indirect diagnostic methods on the basis of urinary galactose determination in the diagnosis of lactose malabsorption with the actual lactase activities. One hundred and seven patients were studied. The specificity and sensitivity of the strip test were 97%.
H, Arola +6 more
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Hypolactasia and Lactase Persistence Historical Review and the Terminology
Scandinavian Journal of Gastroenterology, 1994Lactase (more precisely lactase-phlorizin hydrolase) is located in the brush border of the small intestinal enterocytes and is responsible for the hydrolysis of dietary lactose. The earliest studies on lactase activity in mammals were published around the turn of the century.
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Adult-type hypolactasia in children: A genetic perspective
Journal of Pediatric Biochemistry, 2016Adult-type hypolactasia is an autosomal recessive condition resulting from the physiological decline of the lactase enzyme activity in intestinal cells which occurs in a significant proportion of the global population. Mechanisms proposed to explain the occurrence of adult-type hypolactasia include: (a) decreased production of lactase, (b) synthesis of
Kuchay, Raja A.H. +2 more
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Adult‐type hypolactasia and calcium intake in polycystic ovary syndrome
Clinical Endocrinology, 2012SummaryObjective Adult‐type hypolactasia (ATH) is related to lower calcium and milk intake, which might be associated with obesity and metabolic disturbances. Women with polycystic ovary syndrome (PCOS) frequently suffer from metabolic disturbances including central obesity.
Elisabeth, Lerchbaum +4 more
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