Results 211 to 220 of about 3,173,890 (267)
Some of the next articles are maybe not open access.
Synthesis and biological evaluation of orally active hypolipidemic agents.
Journal of Medicinal Chemistry, 2011A series of novel fenofibric acid ester prodrugs 1c-1h were synthesized and evaluated with the aim of obtaining potent hypolipidemic agents. Prodrugs 1c and 1d exhibited potent hypochlolesterolemic activity, lowering the mice plasma triglyceride level up
B. Bandgar +5 more
semanticscholar +3 more sources
Journal of Medicinal Chemistry, 1992
In the course of further chemical modification of the novel antidiabetic pioglitazone (AD-4833, U-72,107), a series of 5-[4-(2- or 4-azolylalkoxy)benzyl- or -benzylidene]-2,4-thiazolidinediones was prepared and evaluated for hypoglycemic and ...
T. Sohda +5 more
semanticscholar +5 more sources
In the course of further chemical modification of the novel antidiabetic pioglitazone (AD-4833, U-72,107), a series of 5-[4-(2- or 4-azolylalkoxy)benzyl- or -benzylidene]-2,4-thiazolidinediones was prepared and evaluated for hypoglycemic and ...
T. Sohda +5 more
semanticscholar +5 more sources
Exacerbation of Psoriasis by the Hypolipidemic Agent, Gemfibrozil [PDF]
Archives of Dermatology, 1988 To the Editor.— Elicitation or exacerbation of psoriasis has occurred following administration of the psychopharmacologic agents, 1 β-blockers, 2 nonsteroidal anti-inflammatory agents, 3 antimalarials, 4 isotretinoin, 5 and chlorthalidone. 6 Abel and coworkers 7 have extensively analyzed and discussed the entire subject of drug-induced psoriasis in an
Philip L. LeBoit +2 more
openaire +2 more sources
Journal of Natural Products, 2016
Four new pterosin sesquiterpenoids (1-4), a new ent-kaurane diterpenoid (17), and 18 known compounds were isolated from the aerial parts of Pteris cretica L.
Xiangkun Luo +8 more
semanticscholar +1 more source
Four new pterosin sesquiterpenoids (1-4), a new ent-kaurane diterpenoid (17), and 18 known compounds were isolated from the aerial parts of Pteris cretica L.
Xiangkun Luo +8 more
semanticscholar +1 more source
, 2017
Background: Lipid-lowering agents are now the cornerstone of treatment used to reduce the risk of coronary events. Since there is wide variation in selection and use of these drugs, drug utilization studies help to evaluate and analyze drug therapy from ...
Seema R. Gupta +6 more
semanticscholar +1 more source
Background: Lipid-lowering agents are now the cornerstone of treatment used to reduce the risk of coronary events. Since there is wide variation in selection and use of these drugs, drug utilization studies help to evaluate and analyze drug therapy from ...
Seema R. Gupta +6 more
semanticscholar +1 more source
Lentysine: A new hypolipidemic agent from a mushroom
Life Sciences, 1970Abstract The actions of lentysine on the serum and liver lipids in rats have been investigated. Lentysine markedly reduced serum cholesterol, phospholipids and triglycerides, both in intact rats and in animals fed a high fat diet. However, this substance showed no effect on liver lipid levels.
A. Tensho +6 more
openaire +3 more sources
Metabolic Effects of a New Hypolipidemic Agent, Ciprofibrate
Journal of Pharmaceutical Sciences, 1979Ciprofibrate, a new orally effective hypolipidemic agent like clofibrate, suppressed tyloxapol-induced hypercholesterolemia in rats. Ciprofibrate at 10 mg/kg was effective. Clofibrate required a dosage of 180 mg/kg to suppress the tyloxapol effect. Norepinephrine-induced free fatty acid release was inhibited by clofibrate in rats in accordance with ...
A. L. Beyler +2 more
openaire +3 more sources
2006
Publisher Summary Drugs that lower the concentration of lipoproteins in the plasma by inhibiting their production in the organism or by removing them from the plasma are called hypolipidemic or antisclerotic drugs. Atherosclerosis is a condition of the organism characterized by elevated levels of atherogenic lipoproteins in blood plasma, lipid ...
V.J. Hruby, R.S. Vardanyan
openaire +2 more sources
Publisher Summary Drugs that lower the concentration of lipoproteins in the plasma by inhibiting their production in the organism or by removing them from the plasma are called hypolipidemic or antisclerotic drugs. Atherosclerosis is a condition of the organism characterized by elevated levels of atherogenic lipoproteins in blood plasma, lipid ...
V.J. Hruby, R.S. Vardanyan
openaire +2 more sources
Farmacia Hospitalaria, 2013
OBJECTIVE To carry out a structures review of drug interactions of hypolipidemic drugs and to assess their clinical relevance. METHOD Structured review of drug interactions of hypolipidemic drugs in humans through PubMed/Medline of published articles ...
D. Franco +5 more
semanticscholar +1 more source
OBJECTIVE To carry out a structures review of drug interactions of hypolipidemic drugs and to assess their clinical relevance. METHOD Structured review of drug interactions of hypolipidemic drugs in humans through PubMed/Medline of published articles ...
D. Franco +5 more
semanticscholar +1 more source
Synthesis of Potential Hypolipidemic Agents
Journal of Pharmaceutical Sciences, 1969Derivatives of 2-(p-chlorophenoxy)-2-methylpropionic acid (I) and 2-(p-chlorophenylthio)-2-methylpropionic acid (II) have been synthesized for the purpose of studying their potential hypolipidemic activity.
openaire +3 more sources