Results 91 to 100 of about 86,129 (345)
Hyponatremia in Heart Failure: Pathogenesis and Management
Hyponatremia is a very common electrolyte abnormality, associated with poor short- and long-term outcomes in patients with heart failure (HF). Two opposite processes can result in hyponatremia in this setting: Volume overload with dilutional hypervolemic
Mario Rodríguez+8 more
semanticscholar +1 more source
Abstract Background Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with a favorable safety profile demonstrated in preclinical and phase I studies. BRIGHT‐1 aimed to further explore the efficacy and safety of bireociclib monotherapy in patients with locally advanced, recurrent or metastatic, hormone ...
Jiayu Wang+18 more
wiley +1 more source
Hyponatremia in patients with arterial hypertension: pathophysiology and management
Sodium is the main cation in the extracellular space. In physiological conditions, sodium concentration in plasma is 135–145 mmol/l. The kidneys play the most important role in the regulation of sodium homeostasis.
Marcin Adamczak+2 more
doaj +1 more source
Prevalence, Risk Factors, and Short-term Consequences of Traumatic Brain Injury-associated Hyponatremia [PDF]
Hyponatremia, a common electrolyte disorder associated with traumatic brain injuries (TBIs), has high mortality and morbidity rates. The aim of this study was to identify the risk factors for hyponatremia associated with TBI.
Ichiba, Shingo+4 more
core +1 more source
Hyponatremia during hospitalization and in-hospital mortality in patients hospitalized from heart failure [PDF]
BackgroundTo date, the majority of studies on hyponatremia focussed on hyponatremia at admission, and came from developed countries. This study aimed to identify the prevalence of hyponatremia during hospitalization in patients hospitalized for HF and ...
Ball, Patrick A.+2 more
core +1 more source
Oxcarbazepine and hyponatremia [PDF]
Patricia S. Woster, Enrique Carrazana
openalex +4 more sources
Hyponatremia and Hypernatremia: A Practical Guide to Disorders of Water Balance
Hyponatremia and hypernatremia are disorders of water balance and are very common especially in hospitalized patients. Hyponatremia is defined as serum sodium 145 mEq/l (mmol/l).
M. Tinawi
semanticscholar +1 more source
Abstract This study (NCT04537715) investigated itraconazole (strong cytochrome P450 [CYP] 3A inhibitor) and rifampin (strong CYP3A inducer) on tazemetostat pharmacokinetics. In Part 1, patients received tazemetostat 400 mg orally on Days 1, 15, and 36, and 400 mg twice daily on Days 3‐14 and Days 21‐35.
Yingxue Chen+6 more
wiley +1 more source
Hyponatremia after Thyroid Hormone Withdrawal in a Patient with Papillary Thyroid Carcinoma [PDF]
Hyponatremia is an electrolyte abnormality commonly found in clinical practice. It is important to diagnose the underlying etiology of the hyponatremia and correct it appropriately because severe hyponatremia can cause serious complications and ...
Hyo Jin Jo+8 more
doaj +1 more source
Targeting the vasopressin type-2 receptor for renal cell carcinoma therapy. [PDF]
Arginine vasopressin (AVP) and its type-2 receptor (V2R) play an essential role in the regulation of salt and water homeostasis by the kidneys. V2R activation also stimulates proliferation of renal cell carcinoma (RCC) cell lines in vitro.
Calvet, James P+10 more
core