Results 31 to 40 of about 37,277 (211)

Hyponatremic encephalopathy: An uncommon presentation associated with dengue shock syndrome: Two case reports

Journal of Pediatric Critical Care, 2021
Hyponatremia of mild-to-moderate degree is commonly seen in dengue infection. Severe hyponatremia with encephalopathy in dengue infection is rarely seen.
Hasmukh Chapsi Gala
doaj   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Association of hyponatremia with bone mineral density and fractures: a narrative review

Therapeutic Advances in Endocrinology and Metabolism, 2023
Recent studies suggest a possible association of hyponatremia with osteoporosis, falls and bone fractures. The objectives of this narrative review were to further explore this association and the related pathophysiological mechanisms and to suggest a ...
Ploutarchos Tzoulis, Maria P. Yavropoulou   +1 more
doaj   +1 more source

Management Guidelines for the Treatment of Pediatric Brain Tumor–Associated Seizure: A Modified Delphi Consensus Report

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Seizures represent a significant source of morbidity for children with brain tumors. The objective of our study was to establish consensus guidelines for managing children with tumor‐related epilepsy. Methods The study team assembled a panel of 18 child neurologists specializing in neurological complications of brain tumors including
Stephanie N. Brosius, Jacky Ta, Juliane Gust, Fatema Malbari, Mai T. Dang   +4 more
wiley   +1 more source

Etiology, Clinical Approach, and Therapeutic Consequences of Hyponatremia

Kidney and Dialysis
A perturbation in the water balance rather than any change in salt content is the main cause of hyponatremia, the most frequent electrolyte abnormality, defined as a serum sodium concentration 120 mEq/L) or severe (Na < 120 mEq/L) hyponatremia, and is ...
Goce Spasovski
doaj   +1 more source

Influence of Hyponatremia on Spinal Bone Quality and Fractures Due to Low-Energy Trauma

Medicina, 2021
Background and Objectives: Hyponatremia is the most common electrolyte disorder in elderly and associated with increased risk of falls. Clinical studies as well as small animal experiments suggested an association between chronic hyponatremia and ...
Katharina Jäckle, Friederike Klockner, Daniel Bernd Hoffmann, Paul Jonathan Roch, Maximilian Reinhold, Wolfgang Lehmann, Lukas Weiser   +6 more
doaj   +1 more source

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries, Alastair M. Kilpatrick, Kathleen M. Scullion, Rhona Aird, Lorraine Bruce, Maria Elena Candela, Tak Yung Man, Stuart J. Forbes, James W. Dear   +8 more
wiley   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo, Tor Biering‐Sorensen, Joao P. Ferreira, Carlo Mario Lombardi, Andrea Bonelli, Andrea Garascia, Marco Metra, Riccardo M. Inciardi   +7 more
wiley   +1 more source

Hyponatremia in cirrhosis [PDF]

Journal of Hospital Medicine, 2012
AbstractHyponatremia is common in patients with cirrhosis. Portal hypertension, diuretics, large volume paracentesis without albumin, infection, and multiple medications are connected with the development or worsening of hyponatremia. Hyponatremia in cirrhosis, particularly advanced cirrhosis, is a common development.1 In a population survey of 997 ...
openaire   +2 more sources

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source