Results 11 to 20 of about 7,396 (110)
TransCon PTH is an investigational once‐daily prodrug providing sustained release of active PTH designed to maintain stable PTH levels in the physiological range for 24 hours/day. The PaTHway trial met all primary and key secondary endpoints with statistically significant differences from placebo. Most adverse events (AEs) were mild/moderate. Injection‐
Aliya A Khan+19 more
wiley +1 more source
Thyroid nodules in children and adolescents: Investigation and management
Clinically detectable thyroid nodules are less common in children than adults. However, they are associated with an increased risk of malignancy. Therefore, thorough evaluation of paediatric thyroid nodules is necessary, and an understanding of the features associated with a higher risk of malignancy is important to guide management and referral ...
Jessica L Sandy+5 more
wiley +1 more source
Abstract Background Increased cerebrospinal fluid (CSF) protein concentration is a common finding in neurological diseases of dogs. Distinguishing between intrathecally‐produced proteins and proteins that have passed the blood‐CSF barrier because of barrier disruption facilitates diagnosis.
Mirja L. Püschel+4 more
wiley +1 more source
Papillary thyroid carcinoma is treated with thyroidectomy with or without central lymph node dissection (CLND). The risk of permanent hypoparathyroidism after CLND was calculated. The results that indicated that CLND is an independent risk factor for permanent hypoparathyroidism. CLND is associated with permanent hypoparathyroidism Background Papillary
F. A. Salem+3 more
wiley +1 more source
Ionized hypercalcemia in 238 cats from a referral hospital population (2009‐2019)
Abstract Background Ionized calcium concentration ([iCa]) is more sensitive for detecting calcium disturbances than serum total calcium concentration but literature on ionized hypercalcemia in cats is limited. Urolithiasis is a possible adverse consequence of hypercalcemia. Hypothesis/Objectives To describe clinical details of diagnoses associated with
Sophie E. Broughton+3 more
wiley +1 more source
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek+18 more
wiley +1 more source
Abstract Background Clinicopathologic variables predictive of disseminated coccidioidomycosis are known in humans but have not been explored in dogs. Serum 25‐hydroxyvitamin (OH)D correlates with severity of disease of various etiologies in dogs but its role in coccidioidomycosis is unknown.
Jared A. Jaffey+8 more
wiley +1 more source
Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]
Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher+3 more
core +1 more source
Management of Hypoparathyroidism
ABSTRACT Hypoparathyroidism (HypoPT) is a rare disorder characterized by hypocalcemia in the presence of a low or inappropriately normal parathyroid hormone level. HypoPT is most commonly seen after neck surgery, which accounts for approximately 75% of cases, whereas approximately 25% have HypoPT due to nonsurgical causes. In both groups
Aliya A. Khan+19 more
openaire +4 more sources
Hypoparathyroidism in Pregnancy
Hypoparathyroidism is a disorder rarely observed during pregnancy. It poses a major challenge in managing a patient appropriately to prevent maternal and fetal complications. We report a case of a 21-year-old gravid woman, a diagnosed case of hypoparathyroidism.
Samya Janarthanam+3 more
openaire +3 more sources