Recent advances in molecular biology and cytogenetics have made it possible to localize, clone, and characterize some of the genetic abnormalities that result in the hypoparathyroid disorders. Mutations in the parathyroid hormone gene and in the mitochondrial genome have been demonstrated to be associated with some forms of hypoparathyroidism, and ...
Bilezikian, J, Thakker, R
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Hypocalcemia following total thyroidectomy: early factors predicting long-term outcome [PDF]
Hypocalcemia following total thyroidectomy (TT) must be considered permanent in patients requiring calcium replacement therapy after one year. The aim of this study was to identify early risk factors predicting long-term outcome of postoperative ...
Cois, Alessandro+3 more
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From variome to phenome : pathogenesis, diagnosis and management of ectopic mineralization disorders [PDF]
Ectopic mineralization - inappropriate biomineralization in soft tissues - is a frequent finding in physiological aging processes and several common disorders, which can be associated with significant morbidity and mortality.
De Vilder, eva, Vanakker, Olivier
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Jens, Bollerslev+2 more
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Genetics of calcium homeostasis in humans: continuum between monogenic diseases and continuous phenotypes [PDF]
Extracellular calcium participates in several key physiological functions, such as control of blood coagulation, bone calcification or muscle contraction.
Bonny, Olivier, Bochud, Murielle
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Total thyroidectomy without prophylactic central neck dissection in clinically node-negative papillary thyroid cancer: is it an adequate treatment? [PDF]
CALO', PIETRO GIORGIO+6 more
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Mitochondrial disease and endocrine dysfunction [PDF]
Mitochondria are critical organelles for endocrine health; steroid hormone biosynthesis occurs in these organelles and they provide energy in the form of ATP for hormone production and trafficking.
Achermann, JC+4 more
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Mutations of preproparathyroid hormone gene in primary hypoparathyroidism [PDF]
Peptide hormones such as parathyroid hormone (PTH) are processed after translation through steps that are critical for their proper folding, secretion and activity.
Schipani, Ernestina
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Efficacy of Ultrasound-guided Radiofrequency Ablation of Parathyroid Hyperplasia: Single Session vs. Two-Session for Effect on Hypocalcemia [PDF]
To evaluate safety and efficacy of one- vs. two-session radiofrequency ablation (RFA) of parathyroid hyperplasia for patients with secondary hyperparathyroidism (SHPT) and to compare the outcome of both methods on hypocalcemia.
He, Hong-Feng+7 more
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Randomized control study using vitamin d ( calcitriol) in preventing post total thyroidectomy transient hypocalcemia [PDF]
Objective: The aim of our open label randomized control study was to determine the incidence of transient hypocalcemia developing post total thyroidectomy in Kelantan (Malaysia) and the benefit of pre-operative treatment using oral vitamin D for post ...
Chung Ket, Lai
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