Results 41 to 50 of about 7,396 (110)

Finnish nationwide controlled register study found increased inpatient infections in children with 22q11.2 deletion syndrome

Acta Paediatrica, EarlyView.
Abstract Aim Studies on treating infections in children with 22q11.2 deletion syndrome (22q11.2DS) have been limited. We characterised inpatient infections and outpatient antibiotic treatment. Methods Children born during 2005–2018 were eligible for this national Finnish retrospective register‐based study.
Sakari Wahrmann, Leena Kainulainen, Johanna Lempainen, Ville Kytö   +3 more
wiley   +1 more source

Endocrine Abnormalities and Growth Pattern in Single Large‐Scale Mitochondrial DNA Deletion Syndromes

Acta Paediatrica, EarlyView.
ABSTRACT Aim To assess the prevalence of endocrine disorders and investigate growth patterns in single large‐scale mitochondrial DNA deletion syndromes (SLSMDs). Methods A retrospective study of all children with SLSMD who attended Sheba Medical Center, Israel, from February 2017 to September 2024.
Ayman Daka, Einat Lahav, Omer Bar Yosef, Yoav Bolkier, Yael Levy‐Shraga, Yair Anikster, Elad Jacoby, Noah Gruber   +7 more
wiley   +1 more source

Molecular mechanism for transcriptional regulation of the parathyroid hormone gene by Epiprofin

The FEBS Journal, EarlyView.
The secretion of parathyroid hormone (PTH) from the chief cells in the parathyroid glands is regulated by the concentration of extracellular calcium. Epiprofin (Epfn) expression is induced by NFATc2 in response to elevated serum calcium, and Epfn negatively regulates PTH production.
Takashi Nakamura, Hannah M. Nakamura, Yasumasa Iwasaki, Motomi Enomoto‐Iwamoto, Noriaki Nakashima, Satoshi Fukumoto, Maurizio Pacifici, Masahiro Iwamoto, Minoru Wakamori   +8 more
wiley   +1 more source

Correction of both immunodeficiency and hypoparathyroidism by thymus transplantation in complete DiGeorge Syndrome [PDF]

, 2020
Combined immune deficiency due to athymia in patients with complete DiGeorge syndrome can be corrected by allogeneic thymus transplantation. Hypoparathyroidism is a frequent concomitant clinical problem in these patients, which persists after thymus ...
Davies, EG, Hoenig, M, Junghanns, F, Kreins, AY, Mifsud, W, Rampling, D, Schuetz, C, Schulz, A, Sebire, N, Sirin, M, Somana, K, Thrasher, AJ, Worth, A   +12 more
core  

Escherichia coli in the production of biopharmaceuticals

Biotechnology and Applied Biochemistry, Volume 72, Issue 2, Page 528-541, April 2025.
Abstract Escherichia coli has shouldered a massive workload with the discovery of recombinant DNA technology. A new era began in the biopharmaceutical industry with the production of insulin, the first recombinant protein, in E. coli and its use in treating diabetes. After insulin, many biopharmaceuticals produced from E. coli have been approved by the
İbrahim İncir, Özlem Kaplan
wiley   +1 more source

Contextualizing guidelines for the health system of Cyprus: Experiences and lessons learnt

Clinical and Public Health Guidelines, Volume 2, Issue 2, April 2025.
Abstract Background Cyprus is undergoing a major health reform with the recent establishment of the General Healthcare System (GHS). The GHS offers equal healthcare access through one primary insurer (Health Insurance Organization [HIO]) and benefits from a wide collaborative network of public and private healthcare providers.
Panayiotis Kouis, Hugh McGuire, Monika Kyriacou, Anneza Yiallourou, Anastasis Sioftanos, Ourania Kolokotroni, Haris Achilleos, Craig Grime, Pilar Pinilla‐Dominguez, Giorgos Giallouros, Christina Englezou, Contextualization group, George Athanasiou, Elias Avraam, Mary Avraamidou, Anastasios Bagourdis, Charis Charilaou, Stelios Christodoulou, Natasa Christofides, Theodoros Christophides, Vasilis Constantinidis, Dimitris Dimitriou, Stella Eleftheriadou, Christina Flourou, Savvas Frangos, Kyriakos Frantzeskou, Costas Hoplaros, Kyriakos Ioannou, Nikolaos Kadoglou, Chara Kalogirou, Vasileios Karathanos, Andreas Kostis, Andreas Kousios, Ekaterini Lambrinou, Emily Mavrokordatou, Michael Michael, Nicos Mitsides, Chrystalleni Mylonas, Georgia Orphanou, Elias Papasavvas, Doros Polydorou, Stavros Stavrou, Elena Theofanous, Despo Theodorou, Giannis Thrasyvoulou, Chryssa Tziakouri‐Shakalli, Theodora Vassiliou, Alexis Vrachimis, Panayiotis K. Yiallouros, Georgios K. Nikolopoulos   +49 more
wiley   +1 more source

Association of coeliac disease and thyroid disorders [PDF]

, 2008
A case study is presented. This involves a woman who presented with features of hyperthyroidism, which were refractory to conventional therapy. She was eventually diagnosed to have co-existing coeliac disease and eventually improved on a diet excluding ...
Sciberras, Robert
core  

Effect of Histamine‐2 Receptor Antagonists on Hypocalcemia after Thyroidectomy: A Retrospective Cohort Study and Sensitivity Analysis

Otolaryngology–Head and Neck Surgery, Volume 172, Issue 4, Page 1199-1207, April 2025.
Abstract Objective The objective of this study is to examine the risk of hypocalcemia after thyroidectomy in patients taking histamine‐2 receptor antagonists. Study Design Retrospective cohort study. Setting Multicenter, single database. Methods Thirty‐four thousand two hundred eighteen patients treated with total thyroidectomy from 2011 to 2022 were ...
Maxwell Rossip, F Jeffrey Lorenz, Bao Sciscent, Nguyen Truong, Chaitanya Nimmagadda, Neerav Goyal, David Goldenberg   +6 more
wiley   +1 more source

Personalized parathyroid hormone therapy for hypoparathyroidism: Insights from pharmacokinetic‐pharmacodynamic modelling

British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 1233-1240, April 2025.
Aims A 42‐year‐old male developed chronic primary hypoparathyroidism after total thyroidectomy. Conventional therapy led to recurrent nephrolithiasis and therefore rhPTH(1‐84) (parathyroid hormone [PTH]) treatment was considered. According to the dosing guideline for PTH, calcium plasma levels are adequately controlled with once‐daily administration ...
Maira Visscher, Manon Schuls‐Fouchier, Annika M. A. Berends, Anneke C. Muller Kobold, Nieko C. Punt, Daan J. Touw   +5 more
wiley   +1 more source

A Population-based study of the Epidemiology of Chronic Hypoparathyroidism [PDF]

, 2017
There are very few reports on the epidemiology of chronic hypoparathyroidism. A population-based study was undertaken to describe the prevalence and incidence of hypoparathyroidism in Tayside, Scotland.
Donnan, Peter T., Leese, Graham P., Vadiveloo, Thenmalar   +2 more
core   +2 more sources