Comparative efficacy of six therapies for Hypopharyngeal and laryngeal neoplasms: a network meta-analysis [PDF]
BMC Cancer, 2019 Background Hypopharyngeal and laryngeal neoplasms are both fatal and hard to catch in early stages. Yet which treatment is the most efficacious one still remain unanswered.
Juan Che +3 more
doaj +3 more sources
Significance of P53-Binding Protein 1 as a Novel Molecular Histological Marker for Hypopharyngeal Squamous Neoplasms [PDF]
CancersThe DNA damage response protein p53-binding protein 1 (53BP1) accumulates and forms foci at double-strand DNA breaks, indicating the extent of DNA instability. However, the potential role of 53BP1 as a molecular biomarker for hypopharyngeal squamous cell carcinoma (HPSCC) diagnosis remains unknown. Here, we evaluated the potential of immunofluorescence-
Hiroko Kawasaki-Inomata +12 more
core +10 more sources
Diagnostic value, sensitivity and specificity of CT, MRI, and PET in evaluation of cartilage invasion in laryngeal and hypopharyngeal cancer [PDF]
Scientific ReportsIn advanced laryngeal (LSCC) and hypopharyngeal squamous cell carcinoma (HPSCC), concurrent chemoradiation is the standard approach for organ preservation.
Simon E. Thurnheer +4 more
doaj +2 more sources
Type II Hypopharyngeal Defect Reconstruction - a Single Institution Experience [PDF]
Acta Clinica Croatica, 2018 There are several options for hypopharyngeal reconstruction depending on defect size. Reconstructive options include primary closure, local flaps, regional axial flaps or regional intestinal flaps, and free flap transfer with skin or intestinal free ...
Alan Pegan +6 more
doaj +2 more sources
Definitive Radiotherapy with or without Concomitant or Induction Chemotherapy in Patients with Hypopharyngeal Squamous Cell Carcinoma: A Single Center Study in Iran [PDF]
Middle East Journal of Cancer, 2022 Background: Hypopharyngeal carcinoma (HPC) is a rare head and neck cancer which poses many therapeutic challenges. There is limited evidence regarding the outcomes of HPC treatment in Iran.
Ali Kazemian +8 more
doaj +1 more source
Survival Benefits From Surgery for Stage IVa Head and Neck Squamous Cell Carcinoma: A Multi-institutional Analysis of 1,033 Cases [PDF]
Clinical and Experimental Otorhinolaryngology, 2021 Objectives Head and neck squamous cell carcinomas (HNSCs) are frequently diagnosed at the locoregional advanced stage (stage IVa), but controversy remains regarding whether stage IVa HSNCs should be treated with upfront surgery or definitive ...
Jun-Ook Park +18 more
doaj +1 more source
Induction chemotherapy followed by concurrent chemoradiotherapy versus CCRT for locally advanced hypopharynx and base of tongue cancer [PDF]
The Korean Journal of Internal Medicine, 2021 Background/Aims Clinical trials have not consistently supported the use of induction chemotherapy (IC) for locally advanced head and neck squamous cell cancer. Hypopharynx and base of tongue (BOT) cancer has shown relatively poor survival.
Sung Hee Lim +10 more
doaj +1 more source
A novel surgical approach for hypopharyngeal carcinoma resection via the paraglottic space
BMC Surgery, 2021 Background Conservative surgery has proven advantageous in controlling hypopharyngeal squamous cell carcinoma (HSCC) and preserving speech and swallowing function in carefully selected patients, typically with early T-stages diseases.
Wenming Li +6 more
doaj +1 more source
Frontiers in Oncology, 2021 BackgroundSquamous cell cancers in the hypopharynx (HP) and cervical esophagus (CE) are different diseases with different staging systems and treatment approaches.
Xiaoyu Li +42 more
doaj +1 more source
Frontiers in Oncology, 2021 IntroductionWe aimed to analyze the relationship between the changed status of vocal cord mobility and survival outcomes.MethodsSeventy-eight patients with dysfunctional vocal cords and hypopharyngeal carcinomas accepted non-surgical treatment as the ...
Yu-qin He +7 more
doaj +1 more source