Results 11 to 20 of about 9,095 (179)

Insulin‐Like Growth Factor 1 Receptor Expression for Predicting PD‑1/PD‑L1 Inhibitor Response in Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology-Head and Neck Surgery
Objectives Insulin‐like growth factor 1 receptor (IGF‐1R) is crucial for immunological control and the development of different types of cancer. It is still uncertain how the expression of IGF‐1R impacts hypopharyngeal squamous cell carcinoma (HPSCC) and
Wen‐Jing Li, Xiao‐Lin Xu, Li‐Cheng Xu, Shun‐Peng Wang, Yao‐Yao Dong, Yi Wang, Xiao‐Li Ren, Lei Ye, Peng‐Yan Liu, Ming Liu, Lin‐Li Tian   +10 more
doaj   +2 more sources

Survival Benefit of Adjuvant Radiotherapy After Surgery in Patients With T1-2N1M0 Hypopharyngeal Squamous Cell Carcinoma: A Dual-Cohort Analysis of SEER and Institutional Data. [PDF]

Cancer Med
ABSTRACT Background The optimal therapeutic strategy for patients with T2‐3N0‐3 M0 or T1N1‐3 M0 hypopharyngeal squamous cell carcinoma (HPSCC) and the use of postoperative radiotherapy with or without systemic therapy for patients with T1‐2N1M0 HPSCC remain controversial.
Hu Z, Ma R, Wen Y, Deng J, Sun W, Chen L, Chen S, Wen W, Lei W.   +8 more
europepmc   +2 more sources

Spatial Transcriptomics Unveils Landscape of Resistance to Concurrent Chemo-Radiotherapy in Hypopharyngeal Squamous Cell Carcinoma: The Role of SPP1⁺ Macrophages. [PDF]

Cancer Med
ABSTRACT Background Hypopharyngeal squamous cell carcinoma (SCC) is an aggressive malignancy with a poor prognosis, particularly in advanced stages. Concurrent chemoradiotherapy (CCRT) is frequently employed to preserve the larynx, but resistance to CCRT remains a significant clinical challenge.
Ohn J, Bae S, Choi H, Koh J, Kim IG, Chung EJ, Na KJ.   +6 more
europepmc   +2 more sources

I Seed Permanent Implantation as a Palliative Treatment for Stage III and IV Hypopharyngeal Carcinoma [PDF]

Clinical and Experimental Otorhinolaryngology, 2016
Objectives. The aim of this study was to investigate the feasibility and safety of percutaneous 125I seed permanent implantation for advanced hypopharyngeal carcinoma from toxicity, tumor response, and short-term outcome. Methods.
Lei Li, Jie Yang, Xiaojiang Li, Xiaoli Wang, Yanxin Ren, Jimin Fei, Yan Xi, Ruimei Sun, Jing Ma   +8 more
doaj   +1 more source

Large Cervical Osteophytes Mimicking a Hypopharyngeal Neoplasm

American Journal of Medical Case Reports, 2021
Hypertrophic anterior osteophytes of the vertebrae affecting the anterior longitudinal ligament of the spine are typical of diffuse idiopathic skeletal hyperostosis (DISH), a spinal disorder of the elderly also known as Forestier Disease, from the name of the first author who reported it in 1950.
Matteo Pezzoli, Sebastiano Bucolo, Federico Griva, Alessandro Pagliassotto   +3 more
openaire   +1 more source

Reconstruction of Pharyngolaryngeal Defects with the Ileocolon Free Flap: A Comprehensive Review and How to Optimize Outcomes

Archives of Plastic Surgery, 2022
Several reconstructive methods have been reported to restore the continuity of the aerodigestive tract following resection of pharyngeal and hypopharyngeal cancers. However, high complication rates have been reported after voice prosthesis insertion.
Joseph M. Escandón, Eric Santamaría, Peter A. Prieto, Daniela Duarte-Bateman, Pedro Ciudad, Megan Pencek, Howard N. Langstein, Hung-Chi Chen, Oscar J. Manrique   +8 more
doaj   +1 more source

The Role of Open Conservation Surgery in the Era of Minimally Invasive Surgery for Hypopharyngeal Cancer

Medicina, 2023
Background and Objectives: Total laryngectomy with partial pharyngectomy is traditionally the principal curative treatment for hypopharyngeal cancer; however, conservative surgical approaches that minimize functional disability are attracting increasing ...
Jooin Bang, Oh-Hyeong Lee, Geun-Jeon Kim, Dong-Il Sun, Sang-Yeon Kim   +4 more
doaj   +1 more source

Liposarcomas of the hypopharynx: a systematic review of the literature [PDF]

Journal of Health and Social Sciences, 2016
Introduction: Liposarcomas are considered the most common type of soft tissue sarcoma in adults. They represent approximately 20% of all mesenchymal malignancies and most frequently involve the retroperitoneum, trunk and extremities.
Andrea Corvino, Giuseppe Riva, Matteo Sensini, Massimiliano Garzaro, Giancarlo Pecorari   +4 more
doaj   +1 more source

Applied anatomy of the submental island flap and its clinical application in the repair of defects following hypopharyngeal carcinoma resection

World Journal of Otorhinolaryngology-Head and Neck Surgery, 2015
Objective: To explore the feasibility of the submental island flap in the repair of hypopharyngeal defects. Methods: We collected wet specimens of fresh cadaveric heads from the Han Chinese adult population for applied anatomy of the submental island ...
Xi Chen, Han Zhou, Yong-Jie Zhang, Lin Yin, Mei-Ping Lu, Guang-Qian Xing, Zi-Ping Lin, Lei Cheng   +7 more
doaj   +1 more source

Surgically-Treated Locoregionally Advanced Hypopharyngeal Cancer: Outcomes

International Archives of Otorhinolaryngology, 2018
Introduction Hypopharyngeal tumors are head and neck malignancies associated with a great mortality rate, and the treatment of advanced lesions constitutes a challenging problem.
Jorge Rodrigues, Eduardo Breda, Eurico Monteiro   +2 more
doaj   +1 more source