Results 41 to 50 of about 45,942 (277)

Increased PD-L1 and p16 expression are common in oropharyngeal squamous cell carcinoma

Future Science OA, 2021
Overexpression of p16 is closely related to human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (SCC) and pertains a prognostic relevance.
Anna Shestakova, Jana Tarabay, Anton Burtsev, Ifegwu Ibe, Jeffrey Kim, Vishal Chandan, William B Armstrong, Tjoa Tjoson, Beverly Wang   +8 more
doaj   +1 more source

Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort. [PDF]

, 2016
Purpose Treatment with pembrolizumab, an anti-programmed death-1 antibody, at 10 mg/kg administered once every 2 weeks, displayed durable antitumor activity in programmed death-ligand 1 (PD-L1) -positive recurrent and/or metastatic (R/M) head and neck ...
Berger, Raanan, Burtness, Barbara, Cheng, Jonathan D, Chow, Laura QM, Chung, Hyun Cheol, Dolled-Filhart, Marisa, Eder, Joseph Paul, Geva, Ravit, Gupta, Shilpa, Haddad, Robert, Kang, Hyunseok, Keam, Bhumsuk, Lee, Se-Hoon, Lin, Chia-Chi, Mahipal, Amit, Mehra, Ranee, Meister, Amy, Muro, Kei, Pathiraja, Kumudu, Seiwert, Tanguy Y, Tahara, Makoto, Weiss, Jared   +21 more
core   +2 more sources

Uncommon foreign body in the hypopharynx

Medicine, 2018
Rationale: Pharyngeal foreign bodies are a common complaint in emergent cases, and sometimes can be lethal. A large variety of foreign bodies may lodge in the pharynx. We present a case of uncommon foreign body in the hypopharynx.
Guowei Chen, Yizhen Luo, H. Pan, Y. Teng, Z. Liang, Lan Li   +5 more
semanticscholar   +1 more source

Evaluation of Pharyngeal Airway Volume Three-Dimensionally in Various Sagittal Skeletal Patterns - Systematic Review

Indian Journal of Dental Research, 2023
To investigate the pharyngeal airway volume in different anteroposterior skeletal malocclusions. This study was prepared according to the Cochrane criteria for creating a systematic review and meta-analysis and confirms the preferred reporting items for ...
Balaji Rajkumar, Ratna Parameswaran, Mary Sanjana, Srinivasan Boovaraghavan, Devaki Vijayalakshmi   +4 more
doaj   +1 more source

Indication of elective contralateral neck dissection in squamous cell carcinoma of the hypopharynx Indicação do esvaziamento eletivo contralateral no carcinoma espinocelular da hipofaringe

Brazilian Journal of Otorhinolaryngology, 2009
Lymph node metastases (LNM) are common in hypophariyngeal carcinomas; the neck dissection is an important therapeutic approach. AIM: to analyze the incidence and distribution of LNM and failures in treating the contralateral neck.
Ali Amar, Rogério Aparecido Dedivitis, Abrão Rapoport, André Luiz Quarteiro   +3 more
doaj   +1 more source

Lymph node metastasis of squamous cell carcinoma from an unknown primary in the upper and middle neck: impact of 18F-fluorodeoxyglucose positron emission tomography/computed tomography [PDF]

, 2011
Purpose: The purpose of this study was to assess the potential of F-18-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) imaging for detection of the primary tumor and its impact on treatment planning in patients presenting
Bonte, Katrien, Deron, Philippe, Van De Wiele, Christophe, Vermeersch, Hubert   +3 more
core   +1 more source

Oncologic and Functional Outcomes After Primary and Salvage Laryngopharyngoesophagectomy With Gastric Pull-Up Reconstruction for Locally Advanced Hypopharyngeal Squamous Cell Carcinoma

Frontiers in Oncology, 2019
Background/Purpose: Hypopharyngeal squamous cell carcinomas (SCC) are generally diagnosed in an advanced disease stage. A total laryngopharyngoesophagectomy with gastric pull-up reconstruction is a time tested surgical treatment in our centre for ...
Jeroen Meulemans, Jeroen Meulemans, Floor Couvreur, Eline Beckers, Philippe Nafteux, Hans Van Veer, Vincent Vander Poorten, Vincent Vander Poorten, Pierre Delaere, Willy Coosemans   +9 more
doaj   +1 more source

Advanced head and neck cancer: Long-term results of chemo-radiotherapy, complications and induction of second malignancies [PDF]

, 2001
Background: Chemo-radiotherapy is superior to radiotherapy alone in the treatment of advanced, inoperable head and neck cancer. The long-term treatment results, the induction of second malignant tumors, and other long-term toxicities are not well defined.
Aydemir, Ü., Hartenstein, R., Munker, Reinhold, Pohlmann, H., Purmale, L., Reitmeier, M., Schorer, H.   +6 more
core   +1 more source

Recurrent high-grade invasive mucoepidermoid carcinoma of larynx: a case report and review of the literature

Rare Tumors, 2016
Recurrent invasive high-grade mucoepidermoid carcinoma of the larynx and hypopharynx is a rare occurrence. These tumors have been commonly associated with salivary gland tumors, most commonly the parotid gland.
Whitney King, Stephen Ko, Daniel Miller
doaj   +1 more source

Chloride Intracellular Channel 2 Can Function as a Malignant Factor in Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background The association of chloride intracellular channel 2 (CLIC2) with tumors has remained unclear. However, recently, CLIC2 was found to exhibit antitumor properties in some tumors. In this study, we aimed to evaluate the clinical relevance of CLIC2 expression in head and neck squamous cell carcinoma (HNSCC) to determine whether it ...
Yuki Hosokawa, Shoko Miyoshi, Yuji Hayashi, Yuki Irifune, Eriko Sato, Sohei Mitani, Mohammed Choudhury, Hajime Yano, Junya Tanaka, Naohito Hato   +9 more
wiley   +1 more source