Results 71 to 80 of about 45,942 (277)

SUPREME-HN: a retrospective biomarker study assessing the prognostic value of PD-L1 expression in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck. [PDF]

, 2019
BACKGROUND:Programmed cell death ligand-1 (PD-L1) expression on tumor cells (TCs) is associated with improved survival in patients with head and neck squamous cell carcinoma (HNSCC) treated with immunotherapy, although its role as a prognostic factor is ...
Baste, Neus, Clayburgh, Daniel, Cohen, Ezra EW, Fountzilas, George, Fujii, Takashi, Khaliq, Asud, Kim, Edward S, Lin, Derrick, Lipworth, Loren, Mehlhorn, Holger, Melillo, Giovanni, Pai, Sara I, Resteghini, Carlo, Shara, Nawar, Shire, Norah, Stokes, Michael, Twumasi-Ankrah, Philip, Wang, Huifen, Wildsmith, Sophie, Zhang, Jun   +19 more
core   +1 more source

Can Narrow-band Imaging Be Used to Determine the Surgical Margin of Superficial Hypopharyngeal Cancer? [PDF]

, 2008
Narrow-band imaging (NBI) is a novel optical technique that uses narrow bandwidth filters in a video endoscope system to improve the diagnostic capability of endoscopes in characterizing tissues. It is well known that early identification of neoplasia in
Fukushima, Hirofumi, Kawabata, Kazuyoshi, Mitani, Hiroki, Orita, Yorihisa, Tanaka, Shiro, Yamamoto, Noriko, Yoshimoto, Seiichi   +6 more
core   +1 more source

Choice and Death: Analysis of Medical Assistance in Dying for Head and Neck Cancer in Ontario

The Laryngoscope, EarlyView.
The uptake of MAiD for head and neck cancer (HNC) has been steadily increasing since 2016, when MAiD first became available in Canada. Our study projects a substantial increase in the future use of MAiD for patients with HNC. As such, our health system needs to re‐evaluate and implement the necessary infrastructure to support the projected increase in ...
Tanika Curry, Emily Wener, Michael Odell, Lisa Caulley, Rashi Ramchandani, Alyssa Grant, Kednapa Thavorn, Andrea Lasso, Shaun Kilty   +8 more
wiley   +1 more source

Is Dysphagia in Multiple System Atrophy Responsive to Levodopa? Results from a Retrospective Study

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dysphagia remains a major clinical concern in multiple system atrophy (MSA), and so far, lacks relevant treatment options. Objective To systematically assess levodopa‐responsiveness of dysphagia in MSA. Methods 19 MSA‐patients underwent endoscopic swallowing evaluation in Off‐ and On‐state, following an adapted FEES‐levodopa‐test ...
Florin Gandor, Luise Berger, Vera Jäger, Katharina Demmin, Doreen Gruber, Katja Schimming, Paulina Thimm, Georg Ebersbach, Stefanie Schreiber, Dominic Rowe, Annemarie Vogel   +10 more
wiley   +1 more source

Clinical and Socioeconomic Predictors of 60‐Day Rehospitalization After Oncologic Head and Neck Surgery

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Evaluate the association between clinical characteristics and neighborhood socioeconomic disadvantage and 60‐day re‐presentation after oncologic head and neck surgery. Study Design This retrospective cohort study involved 1,088 patients who underwent oncologic head and neck surgery from August 2012 to November 2024.
Nana‐Hawwa Abdul‐Rahman, Shaum Sridharan, Matthew E. Spector, Carl H. Snyderman   +3 more
wiley   +1 more source

Using Beatboxing for Creative Rehabilitation After Laryngectomy:Experiences From a Public Engagement Project [PDF]

, 2020
Laryngectomy is the surgical removal of the larynx (voice box), usually performed in patients with advanced stages of throat cancer. The psychosocial impact of losing the voice is significant, affecting a person’s professional and social life in a ...
Abo-El-Enein, Bohnenkamp, Bussian, Cohen, Danker, de Torcy, Dejonckere, Dooks, Elmiyeh, Gatta, Guo, Gupta, Gupta, Himonides, Jongmans, Kaye, Kent, Keszte, Kitamura, Kleber, Mürbe, O’Grady, Perry, Proctor, Smith, Splinter, Staffieri, Stevens, Stowell, Stowell, Sundberg, van As, Welch, Westra, Wright   +34 more
core   +3 more sources

Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 540-550, March 2025.
ABSTRACT We employed a mechanistic learning approach, integrating on‐treatment tumor kinetics (TK) modeling with various machine learning (ML) models to address the challenge of predicting post‐progression survival (PPS)—the duration from the time of documented disease progression to death—and overall survival (OS) in Head and Neck Squamous Cell ...
Kevin Atsou, Anne Auperin, Jôel Guigay, Sébastien Salas, Sebastien Benzekry   +4 more
wiley   +1 more source

Mutation signature analysis identifies increased mutation caused by tobacco smoke associated DNA adducts in larynx squamous cell carcinoma compared with oral cavity and oropharynx. [PDF]

, 2019
Squamous cell carcinomas of the head and neck (HNSCC) arise from mucosal keratinocytes of the upper aero-digestive tract. Despite a common cell of origin and similar driver-gene mutations which divert cell fate from differentiation to proliferation ...
Curry, Joseph, den Breems, Nicoline Y, Johnson, Jennifer M., Luginbuhl, Adam J., Martinez-Outshoorn, Ubaldo E., Nwagu, Uche, Poojan, Shiv, Richa, Tony, South, Andrew P., Zhan, Tingting   +9 more
core   +1 more source

Association between obstructive apnea syndrome during sleep and damages to anterior labyrinth: Our experience [PDF]

, 2019
The obstructive sleep apnea syndrome is a chronic condition characterized by frequent episodes of collapse of the upper airways during sleep. It can be considered a multisystem disease.
Gallina, S., Marchese, D., Modica, D. M., Speciale, R.   +3 more
core   +1 more source

Hypopharyngeal Surgery in Obstructive Sleep Apnea: A Differential Pattern‑Based Surgical Decision

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background This study aimed to discuss the outcomes after surgical interventions for OSA in patients with hypopharyngeal collapse; the selection of the individual procedure was primarily based on the preoperative endoscopic examination (positional awake endoscopy and DISE) data.
Sherif M. Askar, Nasser N.N. Mohamed, Magdy B. Ali, Mohamed Alshawadfy, Ameer A. Abou Sharkh, Ali Awad   +5 more
wiley   +1 more source