Results 51 to 60 of about 25,098 (228)
Vascular Calcification: Mechanisms, Models, and Therapies
iNew Medicine, EarlyView.ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Journal of Periodontology, EarlyView.Abstract Background Alveolar bone loss challenges tooth retention and implant placement. Freeze‐dried bone allograft (FDBA) is widely used for alveolar ridge preservation but has limitations in resorption rate and healing time. In this proof‐of‐concept study, we tested whether pro‐mineralization enzyme, tissue‐nonspecific alkaline phosphatase (TNAP ...
Kedith Sawangsri +4 more
wiley +1 more source
Effect of ketoconazole-mediated CYP3A4 inhibition on clinical pharmacokinetics of panobinostat (LBH589), an orally active histone deacetylase inhibitor [PDF]
, 2011 Purpose: Panobinostat is partly metabolized by CYP3A4 in vitro. This study evaluated the effect of a potent CYP3A inhibitor, ketoconazole, on the pharmacokinetics and safety of panobinostat.
Paul Hamberg +10 more
core +2 more sources
Nutrition in Clinical Practice, EarlyView.Abstract Preoperative parenteral nutrition (PN) improves outcomes in malnourished surgical patients. Traditionally, this requires hospital admission, increasing length of stay and costs—challenges worsened by limited hospital bed availability. Outpatient PN may offer a feasible alternative.
Narisorn Lakananurak, Leah Gramlich
wiley +1 more source
Treatable Leukoencephalopathy in a Patient with Hypophosphatemia
Case Reports in Neurology, 2017 We report the first patient with pathologically proven leukoencephalopathy associated with hypophosphatemia. A 61-year-old woman had repetitive episodes of decreased consciousness with pontine and pallidal lesions and extensive leukoencephalopathy on MRI,
Masahiro Okazaki +6 more
doaj +1 more source
Fever as a cause of hypophosphatemia in patients with malaria. [PDF]
PLoS ONE, 2007 Hypophosphatemia occurs in 40 to 60% of patients with acute malaria, and in many other conditions associated with elevations of body temperature. To determine the prevalence and causes of hypophosphatemia in patients with malaria, we retrospectively ...
Warren Browner, Richard Haber
doaj +1 more source
European Journal of Dental Education, EarlyView.ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer +4 more
wiley +1 more source
Iron infusion in pregnancy and dental dysplasia in children—is there a link?
Frontiers in PediatricsSome intravenous iron preparations cause hypophosphatemia mediated by increased fibroblast growth factor 23. This hypophosphatemia lasts for weeks or months and, when administered to pregnant women, could affect fetal tooth mineralization, which starts ...
Gabriela Amstad, Tilo Burkhardt
doaj +1 more source
Respiratory failure in a diabetic ketoacidosis patient with severe hypophosphatemia [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2018 Phosphate is essential in regulating human metabolic processes, and severe hypophosphatemia can induce neurologic and hematological complications and result in respiratory failure and cardiac dysfunction.
Han Saem Choi +5 more
doaj +1 more source
Long-term Observation of Osteomalacia Caused by Adefovir-Induced Fanconi’s Syndrome [PDF]
, 2014 A 64-year-old man suffering polyarthralgia and bone pain was referred to our hospital. Renal dysfunction, hypophosphatemia and increased levels of bone alkaline phosphatase were found.
Ebara, Hirotaka +9 more
core +1 more source