Results 81 to 90 of about 25,027 (259)

Severe anaemia secondary to duodenal adenoma in a cat

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 7‐year‐old female, spayed, domestic shorthair presented with a 24‐hour history of anorexia, lethargy and melaena. The cat was hospitalized and received treatment for hypovolemia, various electrolyte abnormalities and severe anaemia with a blood transfusion, intravenous fluids and medications.
Jocosa Yasenchack, Shane Sills, Julianna DiMichele, Julie Byron, Laura E. Selmic   +4 more
wiley   +1 more source

Association between phosphate disturbances and mortality among critically ill patients with sepsis or septic shock

BMC Pharmacology and Toxicology, 2021
Objective The aim of this study is to examine the association of hypophosphatemia and hyperphosphatemia on the first day of ICU admission with mortality in septic critically ill patients. Methods In this retrospective cohort study, all adult patients who
Shmeylan A. Al Harbi, Hasan M. Al-Dorzi, Albatool M. Al Meshari, Hani Tamim, Sheryl Ann I. Abdukahil, Musharaf Sadat, Yaseen Arabi   +6 more
doaj   +1 more source

Hypophosphatemia after high-dose iron repletion with ferric carboxymaltose and ferric derisomaltose—the randomized controlled HOMe aFers study

BMC Medicine, 2020
Background In patients with iron deficiency anemia, ferric carboxymaltose (FCM) and ferric derisomaltose (FDI) allow high-dose iron repletion. While FCM is reported to induce hypophosphatemia, the frequency of hypophosphatemia after an equivalent dosage ...
Insa E. Emrich, Fabio Lizzi, J. Siegel, S. Seiler-Mussler, Christian Ukena, Dominic Kaddu-Mulindwa, R. D’Amelio, Stefan Wagenpfeil, Vincent Brandenburg, Michael Böhm, Danilo Fliser, Gunnar H. Heine   +11 more
semanticscholar   +1 more source

Lysophosphatidic Acid Synergizes With 1,25‐Dihydroxyvitamin D to Promote Fibroblast Growth Factor‐23 Synthesis via MAPK Signaling and Induction of the IL12A Gene

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay, Sajin Marcus Cyr, Yorihiro Iwasaki, Elizabeth Hill, Eugene P. Rhee, Nevil J. Singh, Petra Simic, Murat Bastepe   +7 more
wiley   +1 more source

Monthly triple-dose gadolinium administration: potential associations with leukopenia, hypophosphatemia, and bone marrow T1 hyperintensity

Journal of International Medical Research, 2022
Objective Monthly scanning with triple-dose gadopentetate dimeglumine has been shown to be associated with progressive increases in bone T1 hyperintensity, hypophosphatemia, and leukopenia.
Daniel Chen, Ivan Wolansky, Jaime Imitola, Carl Malchoff, Rong Wu, Suhayl Dhib-Jalbut, Ketan Bulsara, Leo Wolansky   +7 more
doaj   +1 more source

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

Advanced Science, Volume 13, Issue 4, 19 January 2026.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu, Wanyi Zhao, Xinyu Chen, Yanzhou Wang, Shuoshuo Wei, Bo Xiang, Yingzhou Shi, Zongyue Li, Yangyang Yao, Jin Xie, Renyuan Qiu, Meng Shu, Shuo Xu, Ping Chen, Zhiying Chen, Yingjie Wu, Weibo Xia, Ling Gao, Yongfeng Song, Jiajun Zhao, Chao Xu   +20 more
wiley   +1 more source

Nomogram for predicting early hypophosphatemia in term infants

BMC Pediatrics
Background Physiological processes rely on phosphate, which is an essential component of adenosine triphosphate (ATP). Hypophosphatasia can affect nearly every organ system in the body.
Wan Tao, Shina Zhan, Yingjie Shen, Tianjiao Zhao, Feitian Li, Miao Gao, Tingting Yang, Jinqian Yu   +7 more
doaj   +1 more source

Tumor-Induced Osteomalacia in a Patient with Crohn’s Disease: A Case Report and Approach to Investigating Hypophosphatemia

Case Reports in Gastroenterology
Introduction: Hypophosphatemia occurs commonly in inflammatory bowel disease (IBD) patients and can cause considerable morbidity. The differential diagnoses in IBD include nutritional causes and hypophosphatemia induced by some formulations of ...
Kate Hawke, Anthony Croft, Syndia Lazarus   +2 more
doaj   +1 more source

Hyperparathyroidism in Patients With X‐Linked Hypophosphatemia

Journal of Bone and Mineral Research, 2020
X‐linked hypophosphatemia (XLH) is characterized by increased activity of circulating FGF23 resulting in renal phosphate wasting and abnormal bone mineralization. Hyperparathyroidism may develop in XLH patients; however, its prevalence, pathogenesis, and
A. Lecoq, P. Chaumet‐Riffaud, A. Blanchard, M. Dupeux, A. Rothenbuhler, B. Lambert, E. Durand, E. Boros, K. Briot, C. Silve, B. Francou, M. Piketty, P. Chanson, S. Brailly‐Tabard, A. Linglart, P. Kamenickỷ   +15 more
semanticscholar   +1 more source

Nanoparticle Albumin‐Bound Paclitaxel and Nivolumab for PD‐1 Inhibitor‐Refractory Recurrent or Metastatic Head and Neck Squamous‐Cell Carcinoma

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Introduction Standard therapy for PD‐1 inhibitor‐refractory recurrent or metastatic head and neck squamous‐cell carcinoma (RM‐HNSCC) has limited activity. Drugs bound to albumin selectively target cancer cells with upregulated macropinocytosis, a process driven by constitutively hyper‐activated EGFR/RAS/PIK3CA signaling, which is common in ...
Douglas Adkins, Jessica C. Ley, Christine Auberle, Brendan Knapp, Jesse Zaretsky, Jingxia Liu, Peter Oppelt   +6 more
wiley   +1 more source