Results 31 to 40 of about 13,942 (231)
A case of iatrogenic linear streaky hypopigmentation mimicking vitiligo
Pigment InternationalIntralesional corticosteroid (I/L CS) is a frequently used therapy in dermatology that can seldom cause linear hypopigmentation. Very rarely this linear hypopigmentation may present as multiple streaks.
Vibhu Mendiratta +2 more
doaj +1 more source
Serpiginous hypopigmentation secondary to intra-articular corticosteroid injection [PDF]
, 2017 Corticosteroids have been a mainstay of therapy forthe treatment of many inflammatory diseases forwell over 50 years. Cutaneous side effects of localcorticosteroid therapy include striae, thinning of theskin, hypopigmentation, and atrophy, which are ...
Arnold, Jason +2 more
core +1 more source
Molecules, 2017 Tyrosinase is the rate-limiting enzyme critical for melanin synthesis. It controls pigmentation in the skin. Activation of tyrosinase is currently the most common approach in the development of tanning and haircare products.
You Chul Chung +6 more
doaj +1 more source
Melasma-like hyperpigmentation: A rare side effect of imatinib mesylate
Journal of the Scientific Society, 2023 Imatinib mesylate is an oral tyrosine kinase inhibitor used chiefly to treat chronic myeloid leukemia. In the literature, hypopigmentation is a commonly reported side effect of imatinib therapy; however, the cases of melasma-like hyperpigmentation due to
Shreya Agrawal +3 more
doaj +1 more source
Skin Pigmentation Types, Causes and Treatment—A Review
Molecules, 2023 Human skin pigmentation and melanin synthesis are incredibly variable, and are impacted by genetics, UV exposure, and some drugs. Patients’ physical appearance, psychological health, and social functioning are all impacted by a sizable number of skin ...
Amin Mahmood Thawabteh +4 more
doaj +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi +6 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li +6 more
wiley +1 more source
Brazilian Journal of BiologyAnomalous colourations occur in many tropical vertebrates. However, they are considered rare in wild populations, with very few records for the majority of animal taxa. We report two new cases of anomalous colouration in mammals.
MSL. Abreu +4 more
doaj +1 more source
Developmental Dynamics, EarlyView.Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley +1 more source
The role of Rho GTPases in facial morphogenesis
Developmental Dynamics, EarlyView.The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley +1 more source