Results 1 to 10 of about 60,667 (308)
Loss of Melanopsin (OPN4) Leads to a Faster Cell Cycle Progression and Growth in Murine Melanocytes
Current Issues in Molecular Biology, 2021 Skin melanocytes harbor a complex photosensitive system comprised of opsins, which were shown, in recent years, to display light- and thermo-independent functions.
Leonardo Vinícius Monteiro de Assis +5 more
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Amphiregulin Regulates Melanocytic Senescence
Cells, 2021 Oncogene-induced senescence (OIS) is a decisive process to suppress tumor development, but the molecular details of OIS are still under investigation.
Michaela Pommer +2 more
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Human cutaneous interfollicular melanocytes differentiate temporarily under genotoxic stress
iScience, 2022 Summary: DNA-damage response of cutaneous interfollicular melanocytes to fractionated radiotherapy was investigated by immunostaining of tissue sections from punch biopsies collected before, during, and after the treatment of patients for breast cancer ...
Per Fessé +5 more
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Cell Reports, 2015 Molecular signatures specific to particular tumor types are required to design treatments for resistant tumors. However, it remains unclear whether tumors and corresponding cell lines used for drug development share such signatures.
Florian Rambow +13 more
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In vitro dedifferentiation of melanocytes from adult epidermis. [PDF]
PLoS ONE, 2011 In previous work we described a novel culture technique using a cholera toxin and PMA-free medium (Mel-mix) for obtaining pure melanocyte cultures from human adult epidermis.
Bernadett Kormos +7 more
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Mechanisms contributing to differential regulation of PAX3 downstream target genes in normal human epidermal melanocytes versus melanoma cells. [PDF]
PLoS ONE, 2015 Melanoma is a highly aggressive and drug resistant form of skin cancer. It arises from melanocytes, the pigment producing cells of the skin. The formation of these melanocytes is driven by the transcription factor PAX3 early during embryonic development.
Danielle Bartlett +3 more
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Melanosis of the Uterine Cervix: A Rare Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2021 Cervical melanosis is a rare entity in the spectrum of melanocytic lesions of uterine cervix. Melanosis is defined as presence of melanocytes in the basal layer of squamous epithelium causing hyperpigmentation.
Nikhil Sanjay Deshpande +3 more
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Biochemistry and Biophysics Reports, 2019 Mouse melanoma B16-BL6 cells are useful cells for cancer metastatic studies. To understand the metastatic principle at molecular levels, it is necessary to carry out experiments in which cancer cells and their normal counterparts are compared.
Nahoko Tomonobu +8 more
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Melanocytes in the skin--comparative whole transcriptome analysis of main skin cell types. [PDF]
PLoS ONE, 2014 Melanocytes possess several functions besides a role in pigment synthesis, but detailed characteristics of the cells are still unclear. We used whole transcriptome sequencing (RNA-Seq) to assess differential gene expression of cultivated normal human ...
Paula Reemann +8 more
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Journal of the Egyptian Women’s Dermatologic Society, 2020 Background Treatment of vitiligo not responding to conventional therapies involves the replacement of the absent melanocytes by surgical maneuvers, including minigrafting and cultured and noncultured cell suspension grafting.
Tag S Anbar +3 more
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