Results 1 to 10 of about 130,312 (204)
Differential Antifungal Activity of Human and Cryptococcal Melanins with Structural Discrepancies [PDF]
Frontiers in Microbiology, 2017 Melanin is a pigment found in all biological kingdoms, and plays a key role in protection against ultraviolet radiation, oxidizing agents, and ionizing radiation damage. Melanin exerts an antimicrobial activity against bacteria, fungi, and parasites.
Néstor Correa +12 more
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Current Biology, 2020 Melanins are a unique class of pigments found throughout the biosphere with a wide variety of functions, structures, and presentations. Cordero and Casadevall highlight the wide range of places melanins are found and the diverse functions they play in nature.
Radames J B, Cordero, Arturo, Casadevall
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Antioxidants, 2022 Constitutive pigmentation determines the response to sun exposure and the risk for melanoma, an oxidative stress–driven tumor. Using primary cultures of human melanocytes, we compared the effects of constitutive pigmentation on their antioxidant response
Parth R. Upadhyay +5 more
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BMC Medical Education, 2023 Background The number of academic clinicians in the UK is declining and there are demographic inequalities in the clinical-academic workforce. Increased research productivity by medical students is believed to reduce future attrition in the clinical ...
Temidayo Osunronbi +24 more
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Extraction and virulence analysis of melanin from Fonsecaea monophora
Pifu-xingbing zhenliaoxue zazhi, 2023 Objective To construct a mouse model of footpad inoculation with Fonsecaea monophora (F.monophora) melanin, and to analyze the differences in the virulence of F.monophora melanin from different sources.
Huan HUANG +8 more
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Visible light is a better co-inducer of apoptosis for curcumin-treated human melanoma cells than UVA [PDF]
, 2013 Curcumin attracts worldwide scientific interest due to its anti-proliferative and apoptosis inducing effects on different tumor cells at concentrations ranging from 10 to 150 µM (3.7–55 µg/ml).
Bernd, August +7 more
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Nature Communications, 2023 Melanin pigments play a critical role in physiological processes and shaping animal behaviour. Fossil melanin is a unique resource for understanding the functional evolution of melanin but the impact of fossilisation on molecular signatures for eumelanin
Tiffany S. Slater +7 more
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Melanin, melanin "ghosts," and melanin composition in Cryptococcus neoformans [PDF]
Infection and Immunity, 1996 Melanin synthesis is associated with virulence for the pathogenic fungus Cryptococcus neoformans. Exposure of nonmelanized C. neoformans 4067 cells to 4 M guanidinium isothiocyanate followed by 6 M HCl at 100 degrees C resulted in complete solubilization of cellular structures. However, exposure of melanized C.
Y, Wang, P, Aisen, A, Casadevall
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The potential impact of melanosomal pH and metabolism on melanoma
Frontiers in Oncology, 2022 Melanin is synthesized in melanocytes and is transferred into keratinocytes to block the effects of ultraviolet (UV) radiation and is important for preventing skin cancers including melanoma.
Jaewon You +2 more
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The role of melanin in the grapevine trunk disease pathogen Lasiodiplodia gilanensis
Phytopathologia Mediterranea, 2020 Lasiodiplodia (Botryosphaeriaceae) includes fungi that are considered among the most aggressive to grapevine, capable of causing cankers and necrotic lesions which eventually lead to death of host plants.
Edelweiss Airam RANGEL-MONTOYA +3 more
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