Results 1 to 10 of about 80,218 (306)
Chemistry – A European JournalAbstractMelanin is responsible, in Nature, for photoprotection, for this reason it is expected to be poorly photoreactive. However, the photo‐reactivity of melanin and related materials is well documented. Here we discuss some relevant recent examples to demonstrate that, indeed, the actual mechanism of interaction of melanin with light is complex and ...
Menichetti A., Mordini D., Montalti M.
openaire +3 more sources
Binding of Memantine to Melanin: Influence of Type of Melanin and Characteristics
Pharmaceutical Research, 2003 The objectives of this study were to characterize sepia, synthetic, and bovine melanin and to determine their binding characteristics to the drug memantine.Physical methods were used to characterize sepia, synthetic, and bovine melanin. Their binding properties toward memantine were determined in deionized water and phosphate-buffered saline (PBS) at ...
Koeberle, M. +3 more
openaire +5 more sources
Current Biology, 2020 Melanins are a unique class of pigments found throughout the biosphere with a wide variety of functions, structures, and presentations. Cordero and Casadevall highlight the wide range of places melanins are found and the diverse functions they play in nature.
Radames J B, Cordero, Arturo, Casadevall
openaire +3 more sources
Antioxidants, 2022 Constitutive pigmentation determines the response to sun exposure and the risk for melanoma, an oxidative stress–driven tumor. Using primary cultures of human melanocytes, we compared the effects of constitutive pigmentation on their antioxidant response
Parth R. Upadhyay +5 more
doaj +1 more source
BMC Medical Education, 2023 Background The number of academic clinicians in the UK is declining and there are demographic inequalities in the clinical-academic workforce. Increased research productivity by medical students is believed to reduce future attrition in the clinical ...
Temidayo Osunronbi +24 more
doaj +1 more source
Extraction and virulence analysis of melanin from Fonsecaea monophora
Pifu-xingbing zhenliaoxue zazhi, 2023 Objective To construct a mouse model of footpad inoculation with Fonsecaea monophora (F.monophora) melanin, and to analyze the differences in the virulence of F.monophora melanin from different sources.
Huan HUANG +8 more
doaj +1 more source
Melanin, melanin "ghosts," and melanin composition in Cryptococcus neoformans [PDF]
Infection and Immunity, 1996 Melanin synthesis is associated with virulence for the pathogenic fungus Cryptococcus neoformans. Exposure of nonmelanized C. neoformans 4067 cells to 4 M guanidinium isothiocyanate followed by 6 M HCl at 100 degrees C resulted in complete solubilization of cellular structures. However, exposure of melanized C.
Y, Wang, P, Aisen, A, Casadevall
openaire +2 more sources
Nature Communications, 2023 Melanin pigments play a critical role in physiological processes and shaping animal behaviour. Fossil melanin is a unique resource for understanding the functional evolution of melanin but the impact of fossilisation on molecular signatures for eumelanin
Tiffany S. Slater +7 more
doaj +1 more source
The potential impact of melanosomal pH and metabolism on melanoma
Frontiers in Oncology, 2022 Melanin is synthesized in melanocytes and is transferred into keratinocytes to block the effects of ultraviolet (UV) radiation and is important for preventing skin cancers including melanoma.
Jaewon You +2 more
doaj +1 more source
The role of melanin in the grapevine trunk disease pathogen Lasiodiplodia gilanensis
Phytopathologia Mediterranea, 2020 Lasiodiplodia (Botryosphaeriaceae) includes fungi that are considered among the most aggressive to grapevine, capable of causing cankers and necrotic lesions which eventually lead to death of host plants.
Edelweiss Airam RANGEL-MONTOYA +3 more
doaj +1 more source