Results 11 to 20 of about 54,942 (309)

Aging of Melanocytes

open access: yesJournal of Investigative Dermatology, 1979
Choroidal melanocytes of the eyes of postnatal animals are classified as postmitotic terminally differentiated cells. They have specific granules, the melanosomes, which undergo changes qualitatively and quantitatively correlated to the animal's increasing age.
Hu, Funan
openaire   +3 more sources

Human cutaneous interfollicular melanocytes differentiate temporarily under genotoxic stress

open access: yesiScience, 2022
Summary: DNA-damage response of cutaneous interfollicular melanocytes to fractionated radiotherapy was investigated by immunostaining of tissue sections from punch biopsies collected before, during, and after the treatment of patients for breast cancer ...
Per Fessé   +5 more
doaj   +2 more sources

Successful Repigmentation of Full-Thickness Wound Healing in Fraser’s Dolphins (Lagenodelphis hosei)

open access: yesAnimals, 2022
Fraser’s dolphins (Lagenodelphis hosei) exhibit the capability to restore nearly normal pigmentation after full-thickness wounding. However, the association among melanocytes, melanin and skin pigmentation during wound healing in cetaceans has yet to be ...
Chen-Yi Su   +5 more
doaj   +1 more source

Loss of Melanopsin (OPN4) Leads to a Faster Cell Cycle Progression and Growth in Murine Melanocytes

open access: yesCurrent Issues in Molecular Biology, 2021
Skin melanocytes harbor a complex photosensitive system comprised of opsins, which were shown, in recent years, to display light- and thermo-independent functions.
Leonardo Vinícius Monteiro de Assis   +5 more
doaj   +1 more source

Isolation, Culture, and Transfection of Melanocytes. [PDF]

open access: yes, 2023
Located in the basal epidermis and hair follicles, melanocytes of the integument are responsible for its coloration through production of melanin pigments. Melanin is produced in a type of lysosome-related-organelle (LRO) called the melanosome. In humans,
Kohli, JS   +9 more
core   +1 more source

Melanoma Risk and Melanocyte Biology

open access: yesActa Dermato-Venereologica, 2020
Cutaneous melanoma arises from melanocytes following genetic, epigenetic and allogenetic (i.e. other than epi/genetic) modifications. An estimated 10% of cutaneous melanoma cases are due to inherited variants or de novo mutations in approximately 20 ...
Julie U. Bertrand   +4 more
doaj   +1 more source

Amphiregulin Regulates Melanocytic Senescence

open access: yesCells, 2021
Oncogene-induced senescence (OIS) is a decisive process to suppress tumor development, but the molecular details of OIS are still under investigation.
Michaela Pommer   +2 more
doaj   +1 more source

The biology of melanocyte and melanocyte stem cell [PDF]

open access: yesActa Biochimica et Biophysica Sinica, 2014
The melanocyte stem cells of the hair follicle provide an attractive system for the study of the stem cells. Successful regeneration of a functional organ relies on the organized and timely orchestration of molecular events among distinct stem/progenitor cell populations.
openaire   +2 more sources

New Functional Signatures for Understanding Melanoma Biology from Tumor Cell Lineage-Specific Analysis

open access: yesCell Reports, 2015
Molecular signatures specific to particular tumor types are required to design treatments for resistant tumors. However, it remains unclear whether tumors and corresponding cell lines used for drug development share such signatures.
Florian Rambow   +13 more
doaj   +1 more source

Influence of the polyunsaturated fatty acids linoleic acid, arachidonic acid, [alpha]-linolenic acid and [gamma]-linolenic acid on melanogenesis of B16 mouse melanoma cells and normal human melanocytes [PDF]

open access: yes, 2002
The influence of the polyunsaturated fatty acids (PUFA) linoleic acid, arachidonic acid, α-linolenic acid and γ-linolenic acid on pigmentation was examined using different in vitro models: monolayer cultures of B16 mouse melanoma cells, monolayer ...
Stöckli, Martin
core   +1 more source

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