An Investigation of Autoantibodies against Tyrosine Hydroxylase in Patients with Vitiligo [PDF]
, 2012 Vitiligo is an acquired idiopathic hypomelanotic skin disorder characterised by depigmented macules due to loss of cutaneous melanocytes. Evidence suggests that autoimmunity plays a role in the pathogenesis of the disease, since antibodies and T cells ...
Rahoma, Sherif
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Loss of Melanopsin (OPN4) Leads to a Faster Cell Cycle Progression and Growth in Murine Melanocytes
Current Issues in Molecular Biology, 2021 Skin melanocytes harbor a complex photosensitive system comprised of opsins, which were shown, in recent years, to display light- and thermo-independent functions.
Leonardo Vinícius Monteiro de Assis +5 more
doaj +1 more source
Amphiregulin Regulates Melanocytic Senescence
Cells, 2021 Oncogene-induced senescence (OIS) is a decisive process to suppress tumor development, but the molecular details of OIS are still under investigation.
Michaela Pommer +2 more
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Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway [PDF]
, 2009 Melanocortin-1 receptor (MC1R) and its ligands, a-melanocyte stimulating hormone (aMSH) and agouti signaling protein (ASIP), regulate switching between eumelanin and pheomelanin synthesis in melanocytes.
Bennett, DC +36 more
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Human cutaneous interfollicular melanocytes differentiate temporarily under genotoxic stress
iScience, 2022 Summary: DNA-damage response of cutaneous interfollicular melanocytes to fractionated radiotherapy was investigated by immunostaining of tissue sections from punch biopsies collected before, during, and after the treatment of patients for breast cancer ...
Per Fessé +5 more
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Cell Reports, 2015 Molecular signatures specific to particular tumor types are required to design treatments for resistant tumors. However, it remains unclear whether tumors and corresponding cell lines used for drug development share such signatures.
Florian Rambow +13 more
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In vitro dedifferentiation of melanocytes from adult epidermis. [PDF]
PLoS ONE, 2011 In previous work we described a novel culture technique using a cholera toxin and PMA-free medium (Mel-mix) for obtaining pure melanocyte cultures from human adult epidermis.
Bernadett Kormos +7 more
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Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells [PDF]
, 2009 Stem cells, that is, cells that can both reproduce themselves and differentiate into functional cell types, attract much interest as potential aids to healing and disease therapy. Embryonic neural crest is pluripotent and generates the peripheral nervous
Negulyaev, YA +8 more
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Influence of the polyunsaturated fatty acids linoleic acid, arachidonic acid, [alpha]-linolenic acid and [gamma]-linolenic acid on melanogenesis of B16 mouse melanoma cells and normal human melanocytes [PDF]
, 2002 The influence of the polyunsaturated fatty acids (PUFA) linoleic acid, arachidonic acid, α-linolenic acid and γ-linolenic acid on pigmentation was examined using different in vitro models: monolayer cultures of B16 mouse melanoma cells, monolayer ...
Stöckli, Martin
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Isolation, Culture, and Transfection of Melanocytes. [PDF]
, 2023 Located in the basal epidermis and hair follicles, melanocytes of the integument are responsible for its coloration through production of melanin pigments. Melanin is produced in a type of lysosome-related-organelle (LRO) called the melanosome. In humans,
Kohli, JS +9 more
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