Results 31 to 40 of about 55,028 (307)

Melanosis of the Uterine Cervix: A Rare Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Cervical melanosis is a rare entity in the spectrum of melanocytic lesions of uterine cervix. Melanosis is defined as presence of melanocytes in the basal layer of squamous epithelium causing hyperpigmentation.
Nikhil Sanjay Deshpande   +3 more
doaj   +1 more source

‐expressing Schwann cell precursors contribute to skin and cochlear melanocytes, but not to vestibular melanocytes [PDF]

open access: yes, 2020
For a long time, melanocytes were believed to be exclusively derived from neural crest cells migrating from the neural tube toward the developing skin. This notion was then challenged by studies suggesting that melanocytes could also be made from neural ...
Soret, Rodolphe   +5 more
core   +1 more source

Active Notch1 confers a transformed phenotype to primary human melanocytes [PDF]

open access: yes, 2009
The importance of mitogen-activated protein kinase signaling in melanoma is underscored by the prevalence of activating mutations in N-Ras and B-Raf, yet clinical development of inhibitors of this pathway has been largely ineffective, suggesting that ...
Liu, Zhao-Jun   +10 more
core   +1 more source

Developmental Biology of Mammalian Melanocytes [PDF]

open access: yes, 1980
The developmental biology of mammalian cutaneous melanocytes spans the entire life cycle from embryo to senescent adult. This review focuses on the inelanocytes of the epidermis.
Fleischmann, Robert D.   +1 more
core   +1 more source

Repigmentation by outer-root-sheath-derived melanocytes: proof of concept in vitiligo and leucoderma [PDF]

open access: yes, 2009
BACKGROUND: Treatment of depigmented skin is an unmet medical need. OBJECTIVE: Melanocytes or stem cells thereof residing in the outer root sheath (ORS) of hair follicles might be used to repigment skin.
Hunziker, Thomas, Vanscheidt, Wolfgang
core   +1 more source

Imiquimod induces apoptosis of human melanocytes. [PDF]

open access: yes, 2010
Development of vitiligo-like hypopigmentary lesions associated with topical imiquimod has been reported. We hypothesized that mode of action of imiquimod in melanocytes may include triggering of apoptosis resulted in loss of cells, which may be a ...
Joo Hee Ahn   +13 more
core   +1 more source

Melanocytes: A Window into the Nervous System [PDF]

open access: yes, 2012
Melanocytes are pigment-producing cells that originate from the dorsal portions of the closing neural tube in vertebrate embryos. Similar to neurons, they are derived from pluripotent neural crest cells that differentiate into numerous cell lineages. The
Hee-Young Park   +3 more
core   +1 more source

Ultraviolet B irradiation enhances the secretion of exosomes by human primary melanocytes and changes their exosomal miRNA profile.

open access: yesPLoS ONE, 2020
OBJECTIVE:Melanocytes play a central role in skin homeostasis. In this study, we focus on the function of melanocyte releasing exosomes as well as exosomal microRNAs (miRNAs) and investigate whether ultraviolet B (UVB) irradiation exerts an impact on it.
Zeren Shen   +3 more
doaj   +1 more source

Number of keratinocytes and melanocytes in cell suspensions obtained from partial-thickness epidermal cuts and suction blister roofs for vitiligo treatment: a prospective randomized comparative study

open access: yesJournal of the Egyptian Women’s Dermatologic Society, 2020
Background Treatment of vitiligo not responding to conventional therapies involves the replacement of the absent melanocytes by surgical maneuvers, including minigrafting and cultured and noncultured cell suspension grafting.
Tag S Anbar   +3 more
doaj   +1 more source

Defining Wound Healing Progression in Cetacean Skin: Characteristics of Full-Thickness Wound Healing in Fraser’s Dolphins (Lagenodelphis hosei)

open access: yesAnimals, 2022
Cetaceans are tight-skinned mammals that exhibit an extraordinary capacity to heal deep soft tissue injuries. However, essential information of large full-thickness wound healing in cetaceans is still lacking.
Chen-Yi Su   +5 more
doaj   +1 more source

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