Results 31 to 40 of about 55,028 (307)
Melanosis of the Uterine Cervix: A Rare Case Report [PDF]
Cervical melanosis is a rare entity in the spectrum of melanocytic lesions of uterine cervix. Melanosis is defined as presence of melanocytes in the basal layer of squamous epithelium causing hyperpigmentation.
Nikhil Sanjay Deshpande +3 more
doaj +1 more source
‐expressing Schwann cell precursors contribute to skin and cochlear melanocytes, but not to vestibular melanocytes [PDF]
For a long time, melanocytes were believed to be exclusively derived from neural crest cells migrating from the neural tube toward the developing skin. This notion was then challenged by studies suggesting that melanocytes could also be made from neural ...
Soret, Rodolphe +5 more
core +1 more source
Active Notch1 confers a transformed phenotype to primary human melanocytes [PDF]
The importance of mitogen-activated protein kinase signaling in melanoma is underscored by the prevalence of activating mutations in N-Ras and B-Raf, yet clinical development of inhibitors of this pathway has been largely ineffective, suggesting that ...
Liu, Zhao-Jun +10 more
core +1 more source
Developmental Biology of Mammalian Melanocytes [PDF]
The developmental biology of mammalian cutaneous melanocytes spans the entire life cycle from embryo to senescent adult. This review focuses on the inelanocytes of the epidermis.
Fleischmann, Robert D. +1 more
core +1 more source
Repigmentation by outer-root-sheath-derived melanocytes: proof of concept in vitiligo and leucoderma [PDF]
BACKGROUND: Treatment of depigmented skin is an unmet medical need. OBJECTIVE: Melanocytes or stem cells thereof residing in the outer root sheath (ORS) of hair follicles might be used to repigment skin.
Hunziker, Thomas, Vanscheidt, Wolfgang
core +1 more source
Imiquimod induces apoptosis of human melanocytes. [PDF]
Development of vitiligo-like hypopigmentary lesions associated with topical imiquimod has been reported. We hypothesized that mode of action of imiquimod in melanocytes may include triggering of apoptosis resulted in loss of cells, which may be a ...
Joo Hee Ahn +13 more
core +1 more source
Melanocytes: A Window into the Nervous System [PDF]
Melanocytes are pigment-producing cells that originate from the dorsal portions of the closing neural tube in vertebrate embryos. Similar to neurons, they are derived from pluripotent neural crest cells that differentiate into numerous cell lineages. The
Hee-Young Park +3 more
core +1 more source
OBJECTIVE:Melanocytes play a central role in skin homeostasis. In this study, we focus on the function of melanocyte releasing exosomes as well as exosomal microRNAs (miRNAs) and investigate whether ultraviolet B (UVB) irradiation exerts an impact on it.
Zeren Shen +3 more
doaj +1 more source
Background Treatment of vitiligo not responding to conventional therapies involves the replacement of the absent melanocytes by surgical maneuvers, including minigrafting and cultured and noncultured cell suspension grafting.
Tag S Anbar +3 more
doaj +1 more source
Cetaceans are tight-skinned mammals that exhibit an extraordinary capacity to heal deep soft tissue injuries. However, essential information of large full-thickness wound healing in cetaceans is still lacking.
Chen-Yi Su +5 more
doaj +1 more source

