Results 1 to 10 of about 43,130 (164)
JAK Activation Drives MED15-Associated Melanocyte Dysfunction in Vitiligo Beyond Immune Cells [PDF]
Clinical, Cosmetic and Investigational DermatologyJize Wu,1,2,* Yijia Ren,3,* Jiahao Cui,3 Mingjie He,3 Xiaoyu Zhang,4 Dingding Li,1 Na Zhang5 1Scientific Research Management Section, Zhoukou Central Hospital, Zhoukou, Henan, People’s Republic of China; 2First Clinical Medical College ...
Wu J +6 more
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Vitiligo and the melanocyte reservoir
Indian Journal of Dermatology, 2009 Repigmentation of vitiligo depends on available melanocytes from three possible sources: from the hair follicle unit which is the main provider of pigment cells, from the border of vitiligo lesions, and from unaffected melanocytes within depigmented ...
Falabella Rafael
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eLife, 2023 Tissue-resident stem and progenitor cells are present in many adult organs, where they are important for organ homeostasis and repair in response to injury. However, the signals that activate these cells and the mechanisms governing how these cells renew
William Tyler Frantz +5 more
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Frontiers in Cell and Developmental Biology, 2023 Melanoma is the deadliest form of skin cancer and develops from the melanocytes that are responsible for the pigmentation of the skin. The skin is also a highly regenerative organ, harboring a pool of undifferentiated melanocyte stem cells that ...
Esra Katkat +10 more
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The neuropeptide alpha-melanocyte-stimulating hormone is critically involved in the development of cytotoxic CD8+ T cells in mice and humans. [PDF]
PLoS ONE, 2010 BACKGROUND: The neuropeptide alpha-melanocyte-stimulating hormone is well known as a mediator of skin pigmentation. More recently, it has been shown that alpha-melanocyte-stimulating hormone also plays pivotal roles in energy homeostasis, sexual function,
Karin Loser +10 more
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A Study of Normal Epidermal Melanocyte Distribution
International Journal of Dermatology and Venerology, 2021 . Objective:. To elucidate the epidermal melanocyte distribution according to sex, age, and body part with the goal of providing benchmark data for the diagnosis and therapeutic effect evaluation of pigmentary skin diseases. Methods:.
Kai-Lv Sun +4 more
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Melanocytes and Their Diseases [PDF]
Cold Spring Harbor Perspectives in Medicine, 2014 Human melanocytes are distributed not only in the epidermis and in hair follicles but also in mucosa, cochlea (ear), iris (eye), and mesencephalon (brain) among other tissues. Melanocytes, which are derived from the neural crest, are unique in that they produce eu-/pheo-melanin pigments in unique membrane-bound organelles termed melanosomes, which can ...
Yuji, Yamaguchi, Vincent J, Hearing
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Cancer, 1988 The clinical, histopathologic, immunohistochemical, and electron microscopic findings of two cases of melanocytic schwannoma are reported. One case, which occurred in the parotid gland, is believed to be the first reported in this location. The other case was located in the sacral spinal region.
R M, Killeen, C L, Davy, S C, Bauserman
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Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish. [PDF]
PLoS Genetics, 2007 The establishment of a single cell type regeneration paradigm in the zebrafish provides an opportunity to investigate the genetic mechanisms specific to regeneration processes.
Chao-Tsung Yang +3 more
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Frontiers in Cell and Developmental Biology, 2023 Neural crest-derived cells play essential roles in skin function and homeostasis. However, how they interact with environmental cues and differentiate into functional skin cells remains unclear.
Shize Ma +13 more
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