Results 21 to 30 of about 53,753 (240)
Melanogenesis and hypopigmentation: The case of vitiligo
Indian Journal of Dermatology, 2022 Melanocytes are highly specialized dendritic cells that synthesize and store melanin in subcellular organelles called melanosomes, before transfer to keratinocytes.
M Pilar Vinardell +2 more
doaj +1 more source
The First Live-Cell Based Product in The Iranian Drug List; ReColorCell® [PDF]
Cell Journal, 2023 Vitiligo is an autoimmune skin disorder that can significantly affect the quality of life in patients. However, currenttreatment strategies such as phototherapy, topical glucocorticosteroids, or systemic immunosuppressants canbe helpful in vitiligo ...
Mohammad Amin Shahrbaf +2 more
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Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway [PDF]
, 2009 Melanocortin-1 receptor (MC1R) and its ligands, a-melanocyte stimulating hormone (aMSH) and agouti signaling protein (ASIP), regulate switching between eumelanin and pheomelanin synthesis in melanocytes.
Bennett, DC +36 more
core +1 more source
Neoplasia: An International Journal for Oncology Research, 2005 Neuroectodermal tumor cells, like neural crest (NC) cells, are pluripotent, proliferative, and migratory. We tested the hypothesis that genetic programs essential to NC development are activated in neuroectodermal tumors.
Timothy R. Gershon +3 more
doaj +1 more source
Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling
eLife, 2019 Preventing terminal differentiation is important in the development and progression of many cancers including melanoma. Recent identification of the BMP ligand GDF6 as a novel melanoma oncogene showed GDF6-activated BMP signaling suppresses ...
Alec K Gramann +3 more
doaj +1 more source
The melanocyte lineage in development and disease [PDF]
, 2015 Melanocyte development provides an excellent model for studying more complex developmental processes. Melanocytes have an apparently simple aetiology, differentiating from the neural crest and migrating through the developing embryo to specific locations
Mort, Richard L. +2 more
core +6 more sources
Keratinocytes regulate the function of melanocytes
Dermatologica Sinica, 2014 Mammalian keratinocytes compose the bulk of the epithelium, undergo keratinization, and form the dead superficial layer of the skin. These superficial keratinized cells are continuously replaced by cells derived from mitotic cells in the lowest layer of ...
Tomohisa Hirobe
doaj +1 more source
circRNA18_46222157_46248185 inhibits melanogenesis by targeting miR-211/ pathway in goat melanocytes [PDF]
Animal BioscienceObjective This study investigated the effects of circRNA18_46222157_46248185 (named circRNA18) on goat melanogenesis, which differs significantly in goat skins isolated from white and brown coat-colored skins.
Kai Yuan Ji +5 more
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Plants, 2021 Kadsura coccinea (KC), a beneficial plant for human health, has been used for centuries in China, Thailand, and Korea in folk medicine and food. There is evidence supporting the biological effects of highly bioactive ingredients in KC such as lignans ...
Joong Suk Jeon +8 more
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Gnaq and Gna11 in the Endothelin signaling pathway and melanoma
Frontiers in Genetics, 2016 In this article, we first briefly outline the function of G protein coupled receptors in cancer, and then specifically examine the roles of the seven transmembrane G protein coupled Endothelin B receptor (Ednrb) and the G proteins, GNAQ and GNA11, in ...
Oscar eUrtatiz +1 more
doaj +1 more source