Results 21 to 30 of about 69,018 (287)

Avian Pigment Pattern Formation: Developmental Control of Macro- (Across the Body) and Micro- (Within a Feather) Level of Pigment Patterns

Frontiers in Cell and Developmental Biology, 2020
Animal color patterns are of interest to many fields, such as developmental biology, evolutionary biology, ethology, mathematical biology, bio-mimetics, etc. The skin provides easy access to experimentation and analysis enabling the developmental pigment
Masafumi Inaba, Cheng-Ming Chuong
doaj   +1 more source

Unraveling Vitiligo: From Immune Mechanisms to Promising Therapeutic Strategies [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy
Vitiligo is a dermatological condition affecting 1% of the global population, characterized by the loss of skin pigmentation. It appears in two main forms: nonsegmental (symmetrical depigmentation) and segmental (localized depigmentation).
Artur Kovenskiy, Nurlubek Katkenov, Zhussipbek Mukatayev, Almagul Kushugulova   +3 more
doaj   +1 more source

A Simple Drug Delivery System for Platelet-Derived Bioactive Molecules, to Improve Melanocyte Stimulation in Vitiligo Treatment

Nanomaterials, 2020
Vitiligo is the most common depigmentation disorder of the skin. Currently, its therapy focuses on the halting of the immune response and stimulation of the regenerative processes, leading to the restoration of normal melanocyte function.
Karolina Vocetkova, Vera Sovkova, Matej Buzgo, Vera Lukasova, Radek Divin, Michala Rampichova, Pavel Blazek, Tomas Zikmund, Jozef Kaiser, Zdenek Karpisek, Evzen Amler, Eva Filova   +11 more
doaj   +1 more source

Melanoacanthoma of Pinna-Treated with Skin Grafting: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2018
Melanoacanthoma is a very rare cutaneous lesion and it is considered to be a benign neoplasm, which is composed of large dendritic melanocytes and epidermal keratinocytes.
Santosh Uttarkar Pandurangarao, Sridurga Janarthanan, Aravind Darga Ramachandra   +2 more
doaj   +1 more source

Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin

Frontiers in Cell and Developmental Biology, 2023
Neural crest-derived cells play essential roles in skin function and homeostasis. However, how they interact with environmental cues and differentiate into functional skin cells remains unclear.
Shize Ma, Shize Ma, Xiu Li, Xiu Li, Rui Cao, Rui Cao, Guoqin Zhan, Guoqin Zhan, Xin Fu, Xin Fu, Ran Xiao, Ran Xiao, Zhigang Yang, Zhigang Yang   +13 more
doaj   +1 more source

High correlation between skin color based on CIELAB color space, epidermal melanocyte ratio, and melanocyte melanin content [PDF]

PeerJ, 2018
Background To treat skin color disorders, such as vitiligo or burns, melanocytes are transplanted for tissue regeneration. However, melanocyte distribution in the human body varies with age and location, making it difficult to select the optimal donor ...
Wen-Shyan Huang, Yi-Wen Wang, Kun-Che Hung, Pai-Shan Hsieh, Keng-Yen Fu, Lien-Guo Dai, Nien-Hsien Liou, Kuo-Hsing Ma, Jiang-Chuan Liu, Niann-Tzyy Dai   +9 more
doaj   +2 more sources

Modulation of social behavior by the agouti pigmentation gene [PDF]

, 2014
Agouti is a secreted neuropeptide that acts as an endogenous antagonist of melanocortin receptors. Mice and rats lacking agouti (called non-agouti) have dark fur due to a disinhibition of melanocortin signaling and pigment deposition in the hair follicle.
Carola V, Gross CT, Novotny MV, Perlas E, Soini HA, Zonfrillo F   +5 more
core   +1 more source

Pigment Intensity in Dogs is Associated with a Copy Number Variant Upstream of KITLG. [PDF]

, 2020
Dogs exhibit a wide variety of coat color types, and many genes have been identified that control pigment production, appearance, and distribution. Some breeds, such as the Nova Scotia Duck Tolling Retriever (NSDTR), exhibit variation in pheomelanin ...
Affolter, Verena, Bannasch, Danika, Grahn, Robert, Kallenberg, Angelica, Rebhun, Robert, Weich, Kalie, York, Daniel   +6 more
core   +2 more sources

Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing [PDF]

, 2013
It was shown previously that abnormal prohormone processing or inactive proconverting enzymes that are responsible for this processing cause profound obesity.
Cakir, Isin, Cyr, Nicole E., Litvinov, Bogdan Patedakis, Nillni, Eduardo A., Perello, Mario, Romero, Amparo, Stuart, Ronald C.   +6 more
core   +1 more source

MicroRNAs in melanoma development and resistance to target therapy [PDF]

, 2017
microRNAs constitute a complex class of pleiotropic post-transcriptional regulators of gene expression involved in the control of several physiologic and pathologic processes.
Ascierto, Paolo Antonio, Ciliberto, Gennaro, Costantini, Susan, Croce, Carlo M, Fattore, Luigi, Malpicci, Debora, Mancini, Rita, Ruggiero, Ciro Francesco   +7 more
core   +1 more source