Results 21 to 30 of about 43,130 (164)

The First Live-Cell Based Product in The Iranian Drug List; ReColorCell® [PDF]

open access: yesCell Journal, 2023
Vitiligo is an autoimmune skin disorder that can significantly affect the quality of life in patients. However, currenttreatment strategies such as phototherapy, topical glucocorticosteroids, or systemic immunosuppressants canbe helpful in vitiligo ...
Mohammad Amin Shahrbaf   +2 more
doaj   +1 more source

Temporally Regulated Neural Crest Transcription Factors Distinguish Neuroectodermal Tumors of Varying Malignancy and Differentiation

open access: yesNeoplasia: An International Journal for Oncology Research, 2005
Neuroectodermal tumor cells, like neural crest (NC) cells, are pluripotent, proliferative, and migratory. We tested the hypothesis that genetic programs essential to NC development are activated in neuroectodermal tumors.
Timothy R. Gershon   +3 more
doaj   +1 more source

Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling

open access: yeseLife, 2019
Preventing terminal differentiation is important in the development and progression of many cancers including melanoma. Recent identification of the BMP ligand GDF6 as a novel melanoma oncogene showed GDF6-activated BMP signaling suppresses ...
Alec K Gramann   +3 more
doaj   +1 more source

Keratinocytes regulate the function of melanocytes

open access: yesDermatologica Sinica, 2014
Mammalian keratinocytes compose the bulk of the epithelium, undergo keratinization, and form the dead superficial layer of the skin. These superficial keratinized cells are continuously replaced by cells derived from mitotic cells in the lowest layer of ...
Tomohisa Hirobe
doaj   +1 more source

circRNA18_46222157_46248185 inhibits melanogenesis by targeting miR-211/ pathway in goat melanocytes [PDF]

open access: yesAnimal Bioscience
Objective This study investigated the effects of circRNA18_46222157_46248185 (named circRNA18) on goat melanogenesis, which differs significantly in goat skins isolated from white and brown coat-colored skins.
Kai Yuan Ji   +5 more
doaj   +1 more source

A Comparative Study on Photo-Protective and Anti-Melanogenic Properties of Different Kadsura coccinea Extracts

open access: yesPlants, 2021
Kadsura coccinea (KC), a beneficial plant for human health, has been used for centuries in China, Thailand, and Korea in folk medicine and food. There is evidence supporting the biological effects of highly bioactive ingredients in KC such as lignans ...
Joong Suk Jeon   +8 more
doaj   +1 more source

Gnaq and Gna11 in the Endothelin signaling pathway and melanoma

open access: yesFrontiers in Genetics, 2016
In this article, we first briefly outline the function of G protein coupled receptors in cancer, and then specifically examine the roles of the seven transmembrane G protein coupled Endothelin B receptor (Ednrb) and the G proteins, GNAQ and GNA11, in ...
Oscar eUrtatiz   +1 more
doaj   +1 more source

Ocular manifestations of vitiligo: a systematic review

open access: yesBMC Ophthalmology, 2023
Vitiligo is a disorder characterized by loss of epidermal melanocytes, resulting in depigmented macules and patches. While the relationship between ocular pathology and vitiligo has been demonstrated in conditions such as Vogt-Koyanagi-Harada and ...
Tessa LeWitt   +5 more
doaj   +1 more source

Type II Opsins in the Eye, the Pineal Complex and the Skin of Xenopus laevis: Using Changes in Skin Pigmentation as a Readout of Visual and Circadian Activity

open access: yesFrontiers in Neuroanatomy, 2022
The eye, the pineal complex and the skin are important photosensitive organs. The African clawed frog, Xenopus laevis, senses light from the environment and adjusts skin color accordingly.
Gabriel E. Bertolesi   +4 more
doaj   +1 more source

Melanoma Inhibitory Activity (MIA) Is Able to Induce Vitiligo-Like Depigmentation in an in vivo Mouse Model by Direct Injection in the Tail

open access: yesFrontiers in Medicine, 2020
In the complex pathogenesis of vitiligo, the exact mechanism of the dermatosis is still to be clarified. We previously demonstrated that a protein called melanoma inhibitory activity (MIA) is present in non-segmental vitiligo skin and seems to cause the ...
Matteo Bordignon   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy