Results 41 to 50 of about 43,130 (164)

Aging of Melanocytes

Journal of Investigative Dermatology, 1979
Choroidal melanocytes of the eyes of postnatal animals are classified as postmitotic terminally differentiated cells. They have specific granules, the melanosomes, which undergo changes qualitatively and quantitatively correlated to the animal's increasing age.
openaire   +2 more sources

Melanocyte progenitor cells reside in human subcutaneous adipose tissue.

PLoS ONE, 2021
Based on the assumption that some progenitor cells in an organ might reside in neighboring adipose tissue, we investigated whether melanocyte progenitor cells reside in human subcutaneous adipose tissue.
Yuri Ikeda, Akino Wada, Toshio Hasegawa, Mutsumi Yokota, Masato Koike, Shigaku Ikeda   +5 more
doaj   +1 more source

Pigmented intramucosal nevus of gingiva with a special insight on its pathophysiology: Report of a rare entity

Journal of Dr. NTR University of Health Sciences, 2017
Oral melanotic nevi can be characterized as developmental malformations or melanocytic tumors. Nevi are benign in nature originating from proliferating malfunctioning melanoblasts of the neural crest cells either in the epithelium or in connective tissue.
Rithika Bashamalla, Guttikonda V Rao, Surekha Ramulu, Taneeru Sravya   +3 more
doaj   +1 more source

YY1 regulates melanocyte development and function by cooperating with MITF. [PDF]

PLoS Genetics, 2012
Studies of coat color mutants have greatly contributed to the discovery of genes that regulate melanocyte development and function. Here, we generated Yy1 conditional knockout mice in the melanocyte-lineage and observed profound melanocyte deficiency and
Juying Li, Jun S Song, Robert J A Bell, Thanh-Nga T Tran, Rizwan Haq, Huifei Liu, Kevin T Love, Robert Langer, Daniel G Anderson, Lionel Larue, David E Fisher   +10 more
doaj   +1 more source

Low-Dose Melittin Enhanced Pigment Production Through the Upregulation of Tyrosinase Activity and Dendricity in Melanocytes by Limiting Oxidative Stress: A Therapeutic Implication for Vitiligo

Antioxidants
Melittin is a major active ingredient of the bee venom produced by honeybees (Apis mellifera) that exerts various biological effects, such as anti-inflammatory, anti-tumor, anti-microbial, and antioxidant.
Manoj Kumar Tembhre, Shipra
doaj   +1 more source

PAX3: A Driver of Normal Development and Disease

Biomolecules
PAX3 plays a vital role in regulating proper growth, migration, differentiation, and survival during development of normal tissues, including those derived from the embryonic neural crest.
Noah B. Prince, Joyce H. Liang, Theresa M. Rosato, Deborah Lang   +3 more
doaj   +1 more source

Large Melanosome Complex Is Increased in Keratinocytes of Solar Lentigo

Cosmetics, 2017
Solar lentigo (SL) is characterized by macular lesions exhibiting epidermal hyperplasia combined with hyperpigmentation along with irregular elongation of epidermal rete ridges.
Kazuhisa Maeda
doaj   +1 more source

Medical treatment of vitiligo: A narrative review

Pigment International
Vitiligo, a chronic skin condition characterized by depigmentation, poses significant therapeutic challenges. Various medical therapies have been explored to address this disorder, aiming to halt its progression and promote repigmentation.
Anuradha Bishnoi, K.B. Meghana, Davinder Parsad   +2 more
doaj   +1 more source

6-Isoprenylindole-3-carboxylic Acid with an Anti-Melanogenic Activity from a Marine-Derived Streptomyces sp. APA-053

Marine Drugs
In this study, we report the isolation of the known compound 6-isoprenylindole-3-carboxylic acid (SJ196), a prenylated indole derivative, from a marine Streptomyces sp., APA053, and its potent anti-melanogenic activity. SJ196 showed ABTS and DPPH radical
Minjeong Kim, Eun-Young Lee, Ga-Eun Shin, Jungwook Chin, Hongchan An, Sang-Jip Nam, Kyung-Min Lim   +6 more
doaj   +1 more source

Melanocyte Mitogens Induce Both Melanocyte Chemokinesis and Chemotaxis

Journal of Investigative Dermatology, 1995
It is believed that during repigmentation of vitiligo, inactive melanocytes in the outer root sheath of the hair follicle become activated, proliferate, and migrate into the depigmented skin. However, the mechanisms controlling melanocyte migration remain to be elucidated.
Horikawa, Tatsuya, Norris, David A., Yohn, Joseph J., Zekman, Tamara, Travers, Jeffrey B., Morelli, Joseph G.   +5 more
openaire   +2 more sources