Results 11 to 20 of about 53,753 (240)
YY1 regulates melanocyte development and function by cooperating with MITF. [PDF]
PLoS Genetics, 2012 Studies of coat color mutants have greatly contributed to the discovery of genes that regulate melanocyte development and function. Here, we generated Yy1 conditional knockout mice in the melanocyte-lineage and observed profound melanocyte deficiency and
Juying Li +10 more
doaj +2 more sources
, 2003 Iris melanomas are less likely to metastasize than posterior compartment melanomas. The anterior chamber of the eye is an immunosuppressed microenvironment where a wide range of immunosuppressive factors in aqueous humor contribute to the immune ...
Fernando Vidal-Vanaclocha (362083) +7 more
core +5 more sources
An investigation into the role of autoimmunity in vitiligo [PDF]
, 2002 Vitiligo is an acquired depigmenting disorder characterised by the loss of functional melanocytes from the cutaneous epidermis. A role for autoimmunity is supported by the presence of circulating antibodies and T lymphocytes which react against ...
Waterman, Elizabeth Ann
core +6 more sources
, 2003 ?-Melanocyte stimulating hormone (?-MSH) is known to have pleiotrophic functions including pigmentary, anti-inflammatory, antipyretic and immunoregulatory roles in the mammalian body. It is also reported to influence melanoma invasion with levels of ?-, ?
J. W. Haycock (17213647) +10 more
core +5 more sources
, 2004 We reported recently that the inflammatory cytokine tumour necrosis factor ? (TNF-?) can upregulate integrin expression, cell attachment and invasion of cells through fibronectin in a human melanoma cell line (HBL). Furthermore, the actions of TNF-? were
J. W. Haycock (17213647) +7 more
core +5 more sources
Super-High Magnification Dermoscopy in 190 Clinically Atypical Pigmented Lesions
Diagnostics, 2023 Super-high (×400) magnification dermoscopy (D400) is a new non-invasive imaging technique that has been shown to add information for the differential diagnosis of melanocytic lesions in a pilot study.
Elisa Cinotti +8 more
doaj +1 more source
Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2017 Background: Melanocyte of the hair follicle is one of the major sources of repigmentation in vitiligo. Leukotrichia is complete depigmentation with significant bleaching hair.
M. Yulianto Listiawan +2 more
doaj +1 more source
Detection of Cellular Senescence in Human Primary Melanocytes and Malignant Melanoma Cells In Vitro
Cells, 2022 Detection and quantification of senescent cells remain difficult due to variable phenotypes and the absence of highly specific and reliable biomarkers. It is therefore widely accepted to use a combination of multiple markers and cellular characteristics ...
Tom Zimmermann +5 more
doaj +1 more source
A Comparison Between Phorbol 12 Myristate 13 Acetate and Phorbol 12, 13 Dibutyrate in Human Melanocyte Culture [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Melanocyte culture is an integral part of the studies of skin biology and cosmetic applications. After the introduction of selective medium for the culture of human melanocyte using Phorbol 12-myristate13-acetate (PMA) in 1982, a lot of ...
Divya Padma, Kumar M.R. Bhat
doaj +1 more source
PLoS Genetics, 2011 The mechanisms generating stably differentiated cell-types from multipotent precursors are key to understanding normal development and have implications for treatment of cancer and the therapeutic use of stem cells.
Emma R Greenhill +4 more
doaj +1 more source