Results 21 to 30 of about 55,028 (307)

Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway [PDF]

, 2009
Melanocortin-1 receptor (MC1R) and its ligands, a-melanocyte stimulating hormone (aMSH) and agouti signaling protein (ASIP), regulate switching between eumelanin and pheomelanin synthesis in melanocytes.
Bennett, DC, Jimbow, K, Wakamatsu, Kazumasa, Elena V. Sviderskaya, Shosuke Ito, Montoliu, L, Andrew J. Donkin, Tokimasa Hida, Yu, B, Bin Yu, Lluis Montoliu, Donkin, AJ, Wakamatsu, K, Dorothy C. Bennett, Hida, T, Yu, Bin, Millhauser, Glenn L., Bennett, Dorothy C., Barsh, GS, Sviderskaya, Elena V., Sviderskaya, EV, Ito, Shosuke, Lamoreux, ML, Kazumasa Wakamatsu, M. Lynn Lamoreux, Glenn L. Millhauser, Kowichi Jimbow, Lynn Lamoreux, M, Donkin, Andrew J., Lamoreux, M. Lynn, Hida, Tokimasa, Montoliu, Lluís, Gregory S. Barsh, Millhauser, GL, Barsh, Gregory S., Ito, S, Jimbow, Kowichi   +36 more
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Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells [PDF]

, 2009
Stem cells, that is, cells that can both reproduce themselves and differentiate into functional cell types, attract much interest as potential aids to healing and disease therapy. Embryonic neural crest is pluripotent and generates the peripheral nervous
Negulyaev, YA, Bennett, DC, Patel, RH, Sviderskaya, EV, Easty, DJ, Sanchez, DP, Lawrence, MA, Anand, P, Korchev, YE   +8 more
core   +1 more source

New Functional Signatures for Understanding Melanoma Biology from Tumor Cell Lineage-Specific Analysis

Cell Reports, 2015
Molecular signatures specific to particular tumor types are required to design treatments for resistant tumors. However, it remains unclear whether tumors and corresponding cell lines used for drug development share such signatures.
Florian Rambow, Bastien Job, Valérie Petit, Franck Gesbert, Véronique Delmas, Hannah Seberg, Guillaume Meurice, Eric Van Otterloo, Philippe Dessen, Caroline Robert, Daniel Gautheret, Robert A. Cornell, Alain Sarasin, Lionel Larue   +13 more
doaj   +1 more source

In vitro dedifferentiation of melanocytes from adult epidermis. [PDF]

PLoS ONE, 2011
In previous work we described a novel culture technique using a cholera toxin and PMA-free medium (Mel-mix) for obtaining pure melanocyte cultures from human adult epidermis.
Bernadett Kormos, Nóra Belso, Attila Bebes, Gábor Szabad, Sarolta Bacsa, Márta Széll, Lajos Kemény, Zsuzsanna Bata-Csörgo   +7 more
doaj   +1 more source

Influence of the polyunsaturated fatty acids linoleic acid, arachidonic acid, [alpha]-linolenic acid and [gamma]-linolenic acid on melanogenesis of B16 mouse melanoma cells and normal human melanocytes [PDF]

, 2002
The influence of the polyunsaturated fatty acids (PUFA) linoleic acid, arachidonic acid, α-linolenic acid and γ-linolenic acid on pigmentation was examined using different in vitro models: monolayer cultures of B16 mouse melanoma cells, monolayer ...
Stöckli, Martin
core   +1 more source

The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells [PDF]

, 2008
The protein product of the ocular albinism type 1 gene, named OA1, is a pigment cell-specific G protein-coupled receptor exclusively localized to intracellular organelles, namely lysosomes and melanosomes.
Bennett, DC, Venturi C, Palmigiano, A, Schiaffino, MV, Piccirillo, R, Altimare D., Rotondo G., Tacchetti, C, Marigo, V, Bagnato P., Coppola M., Rotondo, G, Venturi, C, Sviderskaya, EV, Palmisano I., Palmigiano A., Altimare D, Bagnato, P, Marigo V., Surace, EM, Altimare, D, Tacchetti C, Innamorati G., Venturi C., Surace E. M., Palmisano I, Rotondo G, INNAMORATI, Giulio, BALLABIO, ANDREA, Schiaffino M. V., Sviderskaya E. V., Palmigiano A, Innamorati G, SURACE, Enrico Maria, Sviderskaya EV, Piccirillo R, Bagnato P, Ballabio A., Incerti B, Piccirillo R., Tacchetti C., Schiaffino MV, Coppola, M, Incerti, B, Bennett DC, Incerti B., Palmisano, I, Coppola M, Bennett D. C., Innamorati, G, Ballabio, A, Marigo V   +51 more
core   +1 more source

Technical Note: The Use of RNA-interference as a Tool to Find Proteins Involved in Melanosome Formation or Transport [PDF]

, 2009
Melanosomes are lysosome-related organelles that produce and transport the pigment melanin within melanocytes. Mutations in proteins required for melanosome transport and formation lead to a range of pigmentation defects, manifested at the cellular level
Daniela Rotin, Eva M. Amsen
core   +2 more sources

Human melanocytes can be isolated, propagated and expanded from plucked anagen hair follicles [PDF]

, 2010
Herein, we report a technically simple method for isolation and culture of human follicular melanocytes based on explant cultures of epilated hair follicles.
Hunziker, Thomas, Dieckmann, Christina, Milkova, Linda, Simon, Jan C, Emmendörffer, Andreas   +4 more
core   +1 more source

Mechanisms contributing to differential regulation of PAX3 downstream target genes in normal human epidermal melanocytes versus melanoma cells. [PDF]

PLoS ONE, 2015
Melanoma is a highly aggressive and drug resistant form of skin cancer. It arises from melanocytes, the pigment producing cells of the skin. The formation of these melanocytes is driven by the transcription factor PAX3 early during embryonic development.
Danielle Bartlett, Glen M Boyle, Mel Ziman, Sandra Medic   +3 more
doaj   +1 more source

Convenient methodology for extraction and subsequent selective propagation of mouse melanocytes in culture from adult mouse skin tissue

Biochemistry and Biophysics Reports, 2019
Mouse melanoma B16-BL6 cells are useful cells for cancer metastatic studies. To understand the metastatic principle at molecular levels, it is necessary to carry out experiments in which cancer cells and their normal counterparts are compared.
Nahoko Tomonobu, Rie Kinoshita, I. Wayan Sumardika, Youyi Chen, Yusuke Inoue, Akira Yamauchi, Ken-ichi Yamamoto, Hitoshi Murata, Masakiyo Sakaguchi   +8 more
doaj   +1 more source