Results 21 to 30 of about 54,942 (309)
Melanosis of the Uterine Cervix: A Rare Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2021 Cervical melanosis is a rare entity in the spectrum of melanocytic lesions of uterine cervix. Melanosis is defined as presence of melanocytes in the basal layer of squamous epithelium causing hyperpigmentation.
Nikhil Sanjay Deshpande +3 more
doaj +1 more source
In vitro dedifferentiation of melanocytes from adult epidermis. [PDF]
PLoS ONE, 2011 In previous work we described a novel culture technique using a cholera toxin and PMA-free medium (Mel-mix) for obtaining pure melanocyte cultures from human adult epidermis.
Bernadett Kormos +7 more
doaj +1 more source
Mechanisms contributing to differential regulation of PAX3 downstream target genes in normal human epidermal melanocytes versus melanoma cells. [PDF]
PLoS ONE, 2015 Melanoma is a highly aggressive and drug resistant form of skin cancer. It arises from melanocytes, the pigment producing cells of the skin. The formation of these melanocytes is driven by the transcription factor PAX3 early during embryonic development.
Danielle Bartlett +3 more
doaj +1 more source
Biochemistry and Biophysics Reports, 2019 Mouse melanoma B16-BL6 cells are useful cells for cancer metastatic studies. To understand the metastatic principle at molecular levels, it is necessary to carry out experiments in which cancer cells and their normal counterparts are compared.
Nahoko Tomonobu +8 more
doaj +1 more source
Animals, 2022 Cetaceans are tight-skinned mammals that exhibit an extraordinary capacity to heal deep soft tissue injuries. However, essential information of large full-thickness wound healing in cetaceans is still lacking.
Chen-Yi Su +5 more
doaj +1 more source
Molecules, 2022 The abundant synthesis and accretion of melanin inside skin can be caused by activation of melanogenic enzymes or increase in number of melanocytes. Melasma is defined as hyperpigmented bright or dark brown spots which are symmetrically distributed and ...
Sukhbir Singh +8 more
doaj +1 more source
‐expressing Schwann cell precursors contribute to skin and cochlear melanocytes, but not to vestibular melanocytes [PDF]
, 2020 For a long time, melanocytes were believed to be exclusively derived from neural crest cells migrating from the neural tube toward the developing skin. This notion was then challenged by studies suggesting that melanocytes could also be made from neural ...
Soret, Rodolphe +5 more
core +1 more source
Cells, 2021 Sanqi, a traditional Chinese herb, is widely used for cardiovascular diseases, and its neuroprotective effects against oxidative stress were recently discovered. The purpose of this study was to investigate whether Sanqi-derived compound K (Sanqi-CK), an
Suwei Tang +6 more
doaj +1 more source
Advanced Therapy Medicinal Products in Vitiligo; Current Status, Future Prospect, and Approved Treatments [PDF]
Cell Journal, 2023 Vitiligo is an auto-immune disease, causing depigmentation of skin in 0.2-1.8% of global population. Topicalcorticosteroids and calcineurin inhibitors are the only treatments with firm evidence of optimal effectiveness withconsiderable side effects ...
Shahriar Ghashghaei +5 more
doaj +1 more source
Repigmentation by outer-root-sheath-derived melanocytes: proof of concept in vitiligo and leucoderma [PDF]
, 2009 BACKGROUND: Treatment of depigmented skin is an unmet medical need. OBJECTIVE: Melanocytes or stem cells thereof residing in the outer root sheath (ORS) of hair follicles might be used to repigment skin.
Hunziker, Thomas, Vanscheidt, Wolfgang
core +1 more source