Results 61 to 70 of about 43,375 (245)

Hypoplastic right heart syndrome, absent pulmonary valve, and non-compacted left ventricle in an adult

open access: yesIndian Heart Journal, 2016
Hypoplastic right heart syndrome is a rare cyanotic congenital heart disease with under-development of the right ventricle, tricuspid, and pulmonary valves leading to right-to-left shunting of the blood through inter-atrial septal defect.
Jagdish C. Mohan   +3 more
doaj   +1 more source

Considering the Genetic Architecture of Hypoplastic Left Heart Syndrome

open access: yesJournal of Cardiovascular Development and Disease, 2022
Hypoplastic left heart syndrome (HLHS) is among the most severe cardiovascular malformations and understanding its causes is crucial to making progress in prevention and treatment.
John W. Belmont
doaj   +1 more source

Behavior and Quality of Life at 6 Years for Children With Hypoplastic Left Heart Syndrome

open access: yesPediatrics, 2019
Behavior and QoL were assessed among an HLHS cohort; sociodemographic factors and indicators of course complexity predicted behavior and QoL outcomes. BrightcoveDefaultPlayer10.1542/6138649651001PEDS-VA_2019-1010 Video Abstract OBJECTIVES: We measured ...
C. Goldberg   +22 more
semanticscholar   +1 more source

Novel SMAD3 Mutation in a Patient with Hypoplastic Left Heart Syndrome with Significant Aortic Aneurysm

open access: yesCase Reports in Genetics, 2014
Aneurysms-osteoarthritis syndrome (AOS) caused by haploinsufficiency of SMAD3 is a recently described cause of syndromic familial thoracic aortic aneurysm and dissection (TAAD).
Kristi K. Fitzgerald   +4 more
doaj   +1 more source

A common variant of hypoplastic left heart syndrome

open access: yesJournal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2017
Hypoplastic left heart syndrome (HLHS) includes a group of closely related anomalies characterized by severe hypoplasia of the left-sided structures of the heart including rudimentary left ventricle, combinations of mitral and aortic valve stenosis, or ...
Ishita Banerji
doaj   +1 more source

Fetal Cerebrovascular Response to Maternal Hyperoxia Testing and Association With Brain Growth and Postnatal Brain Injury in Congenital Heart Disease

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Neurodevelopmental outcomes are impaired in significant congenital heart disease (CHD) with prenatal origins. The cerebrovascular response to maternal hyperoxia (MH) varies in fetuses with CHD, which may reflect brain health in utero.
Mariam Taleb   +6 more
doaj   +1 more source

Changing Epidemiology of Hypoplastic Left Heart Syndrome: Results of a National Swedish Cohort Study

open access: yesJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2019
Background Norwood surgery provides a palliative surgical option for hypoplastic left heart syndrome and has been available in Sweden since 1993. The practice of prenatal ultrasound screening was gradually implemented in the same era, resulting in an ...
A. Öhman   +9 more
semanticscholar   +1 more source

Current surgical options and outcomes for newborns with hypoplastic left heart syndrome

open access: yesAnales de Pediatría (English Edition), 2019
Since the first successful palliation was performed by Norwood et al. in 1983, there have been substantial changes in diagnosis, management, and outcomes of hypoplastic left heart syndrome, Survival for stage 1 palliation has increased to 90% in many ...
Victor Bautista-Hernandez   +3 more
doaj   +1 more source

Infant With Trisomy 18 and Hypoplastic Left Heart Syndrome

open access: yesPediatrics, 2019
Doctors must decide what to do when parents demand cardiac surgery for an infant with trisomy 18 and hypoplastic left heart syndrome. We present a case in which a fetal diagnosis of complex congenital heart disease and trisomy 18 led to a series of ...
Stephanie Kukora   +5 more
semanticscholar   +1 more source

Machine Learning in Identifying Marker Genes for Congenital Heart Diseases of Different Cardiac Cell Types

open access: yesLife
Congenital heart disease (CHD) represents a spectrum of inborn heart defects influenced by genetic and environmental factors. This study advances the field by analyzing gene expression profiles in 21,034 cardiac fibroblasts, 73,296 cardiomyocytes, and 35,
Qinglan Ma   +5 more
doaj   +1 more source

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