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Pregnancies in a patient with congenital absence of prothrombin activity: case report.
American Journal of Perinatology, 1997Congenital hypoprothrombinemias are very rare, inherited disorders in which factor II (prothrombin) levels and/or activity are extremely low or absent. We report eight pregnancies in a patient with this disorder. Obstetric complications attributed to the
V. Catanzarite+3 more
semanticscholar +2 more sources
American Journal of Clinical Pathology, 1980
Prothrombin was assayed using chromogenic substrate of S-2238 for patients who were being treated with coumarin, for patients who had liver disease, and for patients who had congenital hypoprothrombinemias and dysprothrombinemias. In coumarin therapy and
A. Girolami+3 more
semanticscholar +1 more source
Prothrombin was assayed using chromogenic substrate of S-2238 for patients who were being treated with coumarin, for patients who had liver disease, and for patients who had congenital hypoprothrombinemias and dysprothrombinemias. In coumarin therapy and
A. Girolami+3 more
semanticscholar +1 more source
Hemorrhagic diathesis due to factor VII deficiency.
A M A Archives of Internal Medicine, 1957Coagulation disturbances in the second stage of clotting are basically due to deficient generation of thrombin. The prolonged one-stage prothrombin time readily places the defect in the second stage of clotting.
C. P. Barnett
semanticscholar +1 more source
Hypoprothrombinemia Due to Cefamandole
Klinische Wochenschrift, 1988Two patients are described with severe coagulation disturbances, in one instance leading to extensive skin bleeding, secondary to the use of cefamandole. This cefalosporin antibiotic carries the same N-methylthiotetrazole side chain as moxalactam. Pathogenetic mechanisms leading to hypoprothrombinemia, its prevention and treatment are discussed.
Leo Bossaert+3 more
openaire +2 more sources
Cefotetan-associated coagulopathies.
Archives of Surgery, 1989To the Editor .—Two patients from our hospital (Hartford [Conn] Hospital) who developed coagulopathies supposedly from cefotetan were recently described in theArchives.
K. S. Smith+2 more
semanticscholar +1 more source
Lupus, 2023
Objective Children with lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) are characterized by prolonged activated partial thromboplastin time (APTT) and prothrombin time (PT), lupus anticoagulant positivity and low prothrombin (factor II, FII ...
Yanhong Sun+3 more
semanticscholar +1 more source
Objective Children with lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) are characterized by prolonged activated partial thromboplastin time (APTT) and prothrombin time (PT), lupus anticoagulant positivity and low prothrombin (factor II, FII ...
Yanhong Sun+3 more
semanticscholar +1 more source