Results 121 to 130 of about 652 (162)
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Cefazolin-induced hypoprothrombinemia
American Journal of Health-System Pharmacy, 2008A case of cefazolin-induced hypoprothrombinemia in a patient with renal failure is reported.A 50-year-old African-American woman was transferred from the orthopedics service to the internal medicine service for management of acute renal failure. Before her transfer, she had spinal surgery and subsequently developed a wound infection complicated by ...
Amy H, Chung, Kristin, Watson
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Hypoprothrombinemia Associated with Cefmetazole
Annals of Pharmacotherapy, 1997Objective To report a case of hypoprothrombinemia associated with the use of cefmetazole sodium, define patients at risk for this adverse effect, and identify options to prevent this problem. Case Summary A malnourished patient with endstage renal disease received cefmetazole following a below-the-knee amputation of the right leg.
G A, Breen, W L, St Peter
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Hypoprothrombinemia Due to Cefamandole
Klinische Wochenschrift, 1988Two patients are described with severe coagulation disturbances, in one instance leading to extensive skin bleeding, secondary to the use of cefamandole. This cefalosporin antibiotic carries the same N-methylthiotetrazole side chain as moxalactam. Pathogenetic mechanisms leading to hypoprothrombinemia, its prevention and treatment are discussed.
V M, Conraads +3 more
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Hypoprothrombinemia in Naproxen Overdose
Drug Intelligence & Clinical Pharmacy, 1983Transient prolongation of the prothrombin time was observed in the setting of a 10-g overdose of naproxen. The patient reported was previously healthy, without chronic liver disease, bleeding disorders, or malnutrition. The most likely mechanism for this effect is direct inhibition of the synthesis of vitamin-K-dependent clotting factors, possibly via
P K, Waugh, D W, Keatinge
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Antibiotic-associated hypoprothrombinemia
Infectious Diseases Newsletter, 1992Abstract An individual patient's vitamin K status and concomitant risk factors related to underlying disease determine the likelihood of hypoprothrombinemia and bleeding in patients requiring antibiotics. Patients at highest risk should be identified and monitored more aggressively or given prophylactic vitamin K.
Yvonne M. Shevchuk +2 more
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Determinants of Antibiotic‐associated Hypoprothrombinemia
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1987Hypoprothrombinemia is a relatively uncommon event in the hospitalized patient. When it does occur, it often is associated with surgery, dietary vitamin K deficiency, renal dysfunction, malignancy, and broad‐spectrum antibiotic therapy.
J J, Schentag +3 more
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SALICYLATE‐INDUCED HYPOPROTHROMBINEMIA
Acta Medica Scandinavica, 1970Abstract.Four cases of severe hypoprothrombinemia caused by acetylsalicylic acid in therapeutic doses are reported. All cases were verified by positive provocation tests. The hypoprothrombinemia was accompanied by bleeding episodes in two of the four patients.
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Hypoprothrombinemia Associated With Cefoperazone Therapy
Southern Medical Journal, 1987Cefoperazone, a beta-lactam antibiotic with a methylthiotetrazole side chain, has been reported infrequently to cause hypoprothrombinemia and hemorrhage. We retrospectively analyzed the records of 80 patients who had been given this drug for more than 72 hours.
R J, Mueller, D, Green, J P, Phair
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Oral phytonadione in neonatal hypoprothrombinemia
The Journal of Pediatrics, 1959Summary Orally administered phytonadione in doses of 2 mg. of an emulsion given in a dextrose feeding formula on the first day of life is as effective as menadiol sodium biphosphate given intramuscularly in doses of 2.5 mg. in preventing abnormal elevations of the prothrombin time during the first five neonatal days.
M, SHOSHKES, A, EPPLEBAUM, M, WILNER
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Warfarin-Induced Hypoprothrombinemia
JAMA, 1975HYPERTHYROIDISM has been reported to enhance the anticoagulant response to warfarin sodium. 1,2 We believe that the following case of increased sensitivity to warfarin was caused primarily by the patient's hyperthyroid state. Report of a Case A 53-year-old diabetic woman was admitted to the City of Memphis Hospitals in March 1974 for right ...
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