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Hypoprothrombinemia Associated with Cefmetazole
Annals of Pharmacotherapy, 1997Objective To report a case of hypoprothrombinemia associated with the use of cefmetazole sodium, define patients at risk for this adverse effect, and identify options to prevent this problem. Case Summary A malnourished patient with endstage renal disease received cefmetazole following a below-the-knee amputation of the right leg.
G A, Breen, W L, St Peter
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Hypoprothrombinemia Due to Cefamandole
Klinische Wochenschrift, 1988Two patients are described with severe coagulation disturbances, in one instance leading to extensive skin bleeding, secondary to the use of cefamandole. This cefalosporin antibiotic carries the same N-methylthiotetrazole side chain as moxalactam. Pathogenetic mechanisms leading to hypoprothrombinemia, its prevention and treatment are discussed.
V M, Conraads +3 more
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