Results 141 to 150 of about 1,584 (188)

Hypoprothrombinemia as a Complication of Propylthiouracil

JAMA, 1964
PROPYLTHIOURACIL is of recognized value in the therapy of hyperthyroidism and the various adverse reactions to it have been thoroughly reviewed. Leukopenia and agranulocytosis are the most prominent hematologic reactions. In addition, purpura has been described.
openaire   +3 more sources

Hypoprothrombinemia Associated With Cefoperazone Therapy

Southern Medical Journal, 1987
Cefoperazone, a beta-lactam antibiotic with a methylthiotetrazole side chain, has been reported infrequently to cause hypoprothrombinemia and hemorrhage. We retrospectively analyzed the records of 80 patients who had been given this drug for more than 72 hours.
John P. Phair, David Green, Rudolph J. Mueller   +2 more
openaire   +2 more sources

Congenital Hypoprothrombinemia in a Portuguese Family

Thrombosis and Haemostasis, 1973
SummaryA new case of congenital hypoprothrombinemia is described, in which the level of factor II in the propositus has been consistently near 1 per cent. Several specific assays of this factor have been used, including an immunochemical assay that rules out the presence of an abnormal molecule of prothrombin.
Benvindo Justiça, J. M Pina-Cabral
openaire   +3 more sources

Antibiotic-associated hypoprothrombinemia

Infectious Diseases Newsletter, 1992
Abstract An individual patient's vitamin K status and concomitant risk factors related to underlying disease determine the likelihood of hypoprothrombinemia and bleeding in patients requiring antibiotics. Patients at highest risk should be identified and monitored more aggressively or given prophylactic vitamin K.
John Conly, D. Pharm, Yvonne Shevchuk
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Hypoprothrombinemia Associated with Cefamandole [PDF]

Drug Intelligence & Clinical Pharmacy, 1980
Seven patients developed hypoprothrombinemia during the course of cefamandole therapy. In three cases, overt hemorrhaging resulted. After the administration of vitamin K, bleeding stopped and the prothrombin time returned to normal. A significant contributing factor was poor dietary intake, with a mean of 7.3 days with no oral intake.
William Rymer, Cal W. Greenlaw
openaire   +1 more source

Safety concerns of aztreonam: a real-world disproportionality analysis based on FDA adverse event reporting system.

Expert Opinion on Drug Safety
BACKGROUND Aztreonam was approved by the FDA for treating Gram-negative infections, including metallo-β-lactamase producers. This study extensively evaluated aztreonam-related adverse events (AEs) from the FDA Adverse Event Reporting System (FAERS ...
Li-Li Cai, Hong Zhou, Na-Mei Wu, Li-Mian Hong, Zhi-Hang Lin   +4 more
semanticscholar   +1 more source

[Hypoprothrombinemia-lupus anticoagulant syndrome: a case report and literature review].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
The Hypoprothrombinemia-Lupus Anticoagulant Syndrome (HLAS) is a rare coagulation disorder, typically presenting with bleeding manifestations. It is characterized by decreased prothrombin activity and the presence of lupus anticoagulant, but laboratory ...
P. J. Wang, W. Liu, T. Sun, Y. Wang, R. C. Yang, L. Zhang, F. Xue   +6 more
semanticscholar   +1 more source

Potential for False Negative Lupus Anticoagulant Testing in Patients Anticoagulated with Warfarin Using Dilute Russell's Viper Venom Time Assay

Blood
Introduction: Laboratory identification of a lupus anticoagulant (LAC) requires evidence of: a) prolongation of a phospholipid-dependent screening test, usually a LAC-responsive dilute Russell's viper venom time (DRVVT) or activated partial ...
Melissa S Stuart, R. Pruthi, Jansen N Seheult   +2 more
semanticscholar   +1 more source

Determinants of Antibiotic‐associated Hypoprothrombinemia

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1987
Hypoprothrombinemia is a relatively uncommon event in the hospitalized patient. When it does occur, it often is associated with surgery, dietary vitamin K deficiency, renal dysfunction, malignancy, and broad‐spectrum antibiotic therapy. Several mechanisms have been proposed to account for antibiotic‐associated hypoprothrombinemia, including eradication
Thaddeus H. Grasela, Thaddeus H. Grasela, Lynda S. Welage, Lynda S. Welage, Jerome J. Schentag, Jerome J. Schentag, Martin H. Adelman, Martin H. Adelman   +7 more
openaire   +3 more sources

Evaluation of renal resistive index and new biomarkers in post-hepatitis C cirrhosis patients for developing kidney injury

Journal of The Egyptian Society of Nephrology and Transplantation
In liver cirrhosis, hemodynamic changes in splanchnic and systemic circulations are involved. Indeed, no established laboratory markers for altered renal hemodynamics in cirrhosis were implicated.
E. Tony, Mohamed A. A. Abozaid, Amal A. Aziz, M. Abdou, Noha M. Attia, Mostafa H. Othman, Wael A. Abass, Mohammad H. Mostafa   +7 more
semanticscholar   +1 more source