Quantitative evaluation of parotid gland dysfunction in patients with hyposalivation using magnetic resonance imaging mapping technique [PDF]
BMC Oral HealthObjective This study aimed to assess the feasibility of quantitative magnetic resonance imaging (MRI) employing the multi-dynamic multi-echo (MDME) technique as a diagnostic modality for evaluating glandular dysfunction in patients with hyposalivation ...
Chena Lee +5 more
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Investigating the Association Between Smoking and Hyposalivation: A Case–Control Analysis [PDF]
Rambam Maimonides Medical JournalBackground: Xerostomia, or dry mouth, often intensifies oral health problems like dental caries and periodontitis. Smoking is a key factor influencing salivary flow, potentially leading to these issues.
Ambrose Winnifred Christy +3 more
doaj +2 more sources
Current basic and preclinical research for treatment of radiation therapy–induced hyposalivation [PDF]
JADA Foundational ScienceObjectives: Patients receiving radiation therapy (RT) for head and neck cancer experience hyposalivation, a condition that results in loss of oral health and significantly decreases the quality of life of millions of patients worldwide.
Olga J. Baker, DDS, PhD +2 more
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Minor salivary flow as a diagnostic tool for screening hyposalivation in Medication-Induced Xerostomia [PDF]
BMC Oral HealthBackground We aimed to determine whether minor salivary flow (MSF) rate, measured via a rapid paper-based test, can serve as a reliable screening tool for detecting hyposalivation.
Sanjana Santhosh Kumar +7 more
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Exploring the salivary proteome following intraglandular mesenchymal stromal cell therapy for radiation-induced hyposalivation in previous head and neck cancer patients: a secondary study protocol for the MESRIX-III, randomised, controlled trial [PDF]
TrialsBackground Intraglandular therapy with adipose-derived mesenchymal stromal cells (ASCs) for radiation-induced xerostomia and hyposalivation has shown promising effects on the salivary flow rate and in patient-reported outcomes.
Amanda-Louise Fenger Carlander +9 more
doaj +2 more sources
Engineered nanozyme immunomodulator for xerostomia treatment via regulating submandibular salivary gland [PDF]
Materials Today BioXerostomia, or dry mouth, manifests as a symptom of hyposalivation. Current clinical management primarily relies on palliative therapies to alleviate symptoms.
Xinyu Tao +6 more
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Loss of tricellular tight junction tricellulin leads to hyposalivation in Sjögren’s syndrome [PDF]
International Journal of Oral ScienceTricellulin, a key tricellular tight junction (TJ) protein, is essential for maintaining the barrier integrity of acinar epithelia against macromolecular passage in salivary glands.
Xiangdi Mao +9 more
doaj +2 more sources
Prevalence of hyposalivation and associated factors in survivors of head and neck cancer treated with radiotherapy [PDF]
Journal of Applied Oral Science, 2021 Hyposalivation and sensation of dry mouth (xerostomia) are one of the most common adverse effects in the treatment of patients with head and neck cancer.
Riéli Elis Schulz +6 more
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Oral and systemic factors in xerostomia
RGO: Revista Gaúcha de Odontologia, 2021 Objective: The aim of this study was to evaluate the relationship among the following features: hyposalivation, systemic diseases and drug use, oral symptoms, dental condition, salivary flow and salivary pH, as well. Methods: A cross-sectional study was
Maria Sueli Marques SOARES +3 more
doaj +1 more source
Hyposalivation and Xerostomia: Prevalence and Associated Factors in the Elderly
Medical Sciences Forum, 2023 In the elderly, many chronic diseases and systemic conditions, medications, and salivary dysfunctions, mostly caused by therapeutic radiation and chemotherapy, are associated with hyposalivation and xerostomia, affecting quality of life.
Inês Caetano Santos +7 more
doaj +1 more source