Results 11 to 20 of about 20,626 (220)

Severity-Dependent Profile of the Metabolome in Hypospadias

open access: yesFrontiers in Pediatrics, 2020
Background & Objective: Hypospadias, characterized by the displacement of the opening of the urethra at any point in the medial-ventral side of the penis, is classified upon severity as mild (Type I) and severe (Type II and Type III) hypospadias ...
Coriness Piñeyro-Ruiz   +3 more
doaj   +1 more source

Parental risk factors associated with hypospadias

open access: yesArchives of Medicine and Health Sciences, 2013
Introduction: Hypospadias is one of the most common congenital anomalies of male external genitalia. It occurs in approximately 1 in 250 newborn. Hypospadias can be defined as an abnormal urethral orifice under surface of the penis with or without ...
Bindhu Suma Shekar, Ramakrishna Avadhani
doaj   +1 more source

Can Testosterone Alter the Degree of Hypospadias? A Comprehensive Study

open access: yesJournal of Indian Association of Pediatric Surgeons, 2021
Context: In this study, we observed using serial injections of parenteral testosterone whether we can alter the degree of hypospadias. Aims: The aim was to study the effect of testosterone on different parts of the phallus in hypospadias and to see if we
Dasmit Singh Khokar, Ravi Vadilal Patel
doaj   +1 more source

Association between perinatal factors and hypospadias in newborns: a retrospective case–control study of 42,244 male infants

open access: yesBMC Pregnancy and Childbirth, 2022
Background Hypospadias is one of the most common male congenital malformations worldwide. It is characterised by the abnormal positioning of the opening of urethra, and may lead to problems with urination and sexual function.
Yi Wang   +5 more
doaj   +1 more source

Profile of Hypospadias Cases in Central Java, Indonesia

open access: yesJournal of Biomedicine and Translational Research, 2015
Background: Hypospadia is believed to be a multifactorial disease.  The risk factors that may induce the formation of hypospadias are environmental factors, endocrine disruptors, and genetic factors.
Ziske Maritska   +4 more
doaj   +1 more source

Dysregulated expression of androgen metabolism genes and genetic analysis in hypospadias

open access: yesMolecular Genetics & Genomic Medicine, 2020
Background The aberrant expression of genes involved in androgen metabolism and genetic contribution are unclear in hypospadias. Methods We compared gene expression profiles by RNA sequencing from five non‐hypospadiac foreskins, five mild hypospadiac ...
Zhongzhong Chen   +4 more
doaj   +1 more source

Publication Bias in Randomized Controlled Trials of Hypospadias Surgical Repair: A Systematic Review. [PDF]

open access: yesInt J Urol
ABSTRACT Objectives Hypospadias is a common congenital condition in males that has been subject to extensive research. However, publication bias can distort the scientific literature and impact clinical decision‐making. This review evaluates publication bias in hypospadias research and emphasizes the need for balanced reporting to improve clinical ...
Nainggolan E   +6 more
europepmc   +2 more sources

Genetic and other epidemiological risk factors of infants and children with hypospadias: a case control study

open access: yesAfrican Journal of Urology, 2023
Background To study hypospadias as regard epidemiological risk factors and genetic association with mutations in Steroid 5 alpha reductase type 2 genes.
Wafaa Moustafa   +4 more
doaj   +1 more source

Risks of Birth Defects Following In Utero Exposures to Unregulated Brominated Haloacetic Acids. [PDF]

open access: yesBirth Defects Res
ABSTRACT Introduction Haloacetic acids (HAAs) are water disinfection byproducts (DBPs) regulated as a mixture of five species (HAA5) in the United States and Canada. To date, two brominated HAAs (BrHAAs) in HAA5 (monobromoacetic acid [MBAA], dibromoacetic acid [DBAA]) have been associated with birth defects in some epidemiologic studies, but the other ...
Kaufman JA, Wright JM.
europepmc   +2 more sources

Polymorphism of PvuII, Xba1, and SNP 12 Estrogen Receptor 1 (ESR1) in Hipospadias Patients at Tertiary Hospital Center

open access: yesResearch and Reports in Urology, 2021
Safendra Siregar,1 Jupiter Sibarani,1 Bambang Sasongko Noegroho,1 Irfan Firmansyah,1 Ani Melani Maskoen2 1Department of Urology, Faculty of Medicine Universitas Padjadjaran, General Hospital Hasan Sadikin Bandung, Indonesia; 2Department of Molecular ...
Siregar S   +4 more
doaj  

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