Results 11 to 20 of about 34,310 (236)
Advances in Urology, 2008 Objective. The great possibility of variations in the clinical presentation of hypospadia, makes its therapy challenging. This has led to the development of a number of techniques for hypospadia repair. This article assesses past and present concepts and operative techniques with the aim of broadening our understanding of this malformation.Materials ...
N. Djakovic +3 more
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Soft tissue reinforcement interposition flaps in hypospadias repair
Indian Journal of Plastic Surgery, 2007 Purpose: To discuss the role and mechanism of action of soft tissue reinforcement interposition flaps (strifs) in hypospadias repairs (reinforced hypospadiac urethroplasties).
R B Singh +3 more
doaj +1 more source
The spectrum of phenotypes associated with mutations in steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) includes severe penoscrotal hypospadias in 46,XY males without adrenal insufficiency [PDF]
, 2009 OBJECTIVE. Hypospadias is a frequent congenital anomaly but in most cases an underlying cause is not found. Steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) is a key regulator of human sex development and an increasing number of SF-1 (NR5A1) mutations are ...
Achermann, J.C. +9 more
core +2 more sources
Ecotoxicology and Environmental Safety, 2022 Hypospadias and cryptorchidism are the most common congenital malformations in male neonates, both of which are also the important clinical manifestations of testicular dysgenesis syndrome and share a same origin.
Xiang Zhou +11 more
doaj +1 more source
Renal Subcapsular xenografing of human fetal external genital tissue - A new model for investigating urethral development. [PDF]
, 2017 In this paper, we introduce our novel renal subcapsular xenograft model for the study of human penile urethral and clitoral development. We grafted fifteen intact fetal penes and clitorides 8-11 weeks fetal age under the renal capsules of gonadectomized ...
Baskin, Laurence +6 more
core +2 more sources
Flutamide-induced hypospadias in rats: A critical assessment. [PDF]
, 2017 This paper provides the first detailed description of flutamide-induced hypospadias in the rat based upon wholemount, histologic, three-dimensional reconstruction, scanning electron microscopic, and immunocytochemical analysis.
Baskin, Laurence +4 more
core +2 more sources
Plastic and Reconstructive Surgery, 1966 Presentado en sesión de 12 de setiembre de ...
PATRICK CLARKSON +2 more
openaire +4 more sources
Parental risk factors associated with hypospadias
Archives of Medicine and Health Sciences, 2013 Introduction: Hypospadias is one of the most common congenital anomalies of male external genitalia. It occurs in approximately 1 in 250 newborn. Hypospadias can be defined as an abnormal urethral orifice under surface of the penis with or without ...
Bindhu Suma Shekar, Ramakrishna Avadhani
doaj +1 more source
Synergistic disruption of external male sex organ development by a mixture of four antiandrogens [PDF]
, 2009 Reproduced with permission from Environmental Health Perspectives.Background: By disrupting the action of androgens during gestation, certain chemicals present in food, consumer products, and the environment can induce irreversible demasculinization and ...
Andreas Kortenkamp +14 more
core +3 more sources
Can Testosterone Alter the Degree of Hypospadias? A Comprehensive Study
Journal of Indian Association of Pediatric Surgeons, 2021 Context: In this study, we observed using serial injections of parenteral testosterone whether we can alter the degree of hypospadias. Aims: The aim was to study the effect of testosterone on different parts of the phallus in hypospadias and to see if we
Dasmit Singh Khokar, Ravi Vadilal Patel
doaj +1 more source