Results 11 to 20 of about 47,634 (314)

Association between perinatal factors and hypospadias in newborns: a retrospective case–control study of 42,244 male infants

open access: yesBMC Pregnancy and Childbirth, 2022
Background Hypospadias is one of the most common male congenital malformations worldwide. It is characterised by the abnormal positioning of the opening of urethra, and may lead to problems with urination and sexual function.
Yi Wang   +5 more
doaj   +2 more sources

Dysregulated expression of androgen metabolism genes and genetic analysis in hypospadias

open access: yesMolecular Genetics & Genomic Medicine, 2020
Background The aberrant expression of genes involved in androgen metabolism and genetic contribution are unclear in hypospadias. Methods We compared gene expression profiles by RNA sequencing from five non‐hypospadiac foreskins, five mild hypospadiac ...
Zhongzhong Chen   +4 more
doaj   +2 more sources

Is there an ideal age for hypospadias repair? A pilot study [PDF]

open access: green, 2009
OBJECTIVE: To assess whether repairing hypospadias before or after 18 months affects psychological adjustment, health-related quality of life (HRQoL) and surgical outcome.
Gerber, A   +4 more
core   +2 more sources

Identification of gene variants in 130 Han Chinese patients with hypospadias by targeted next‐generation sequencing

open access: yesMolecular Genetics & Genomic Medicine, 2019
Background Hypospadias is a common congenital malformation of male external genitalia, which mainly manifests as an abnormal urethral opening on the ventral side of the penis.
Wanyu Zhang   +12 more
doaj   +2 more sources

Hypospadias: A Comprehensive Review Including Its Embryology, Etiology and Surgical Techniques

open access: yesCureus, 2022
Hypospadias is among the most prevalent urogenital malformations in male newborns. It is characterized by the displacement of the urethral meatus to the ventral side of the penis, an aberrant ventral curve of the penis referred to as "chordee," and an ...
S. Halaseh   +2 more
semanticscholar   +1 more source

Hypospadias: clinical approach, surgical technique and long-term outcome

open access: yesBMC Pediatrics, 2021
Background Hypospadias is one of the most common congenital abnormalities in male newborn. There is no universal approach to hypospadias surgical repair, with more than 300 corrective procedures described in current literature.
P. Ceccarelli   +6 more
semanticscholar   +1 more source

Parental Concerns of Boys with Hypospadias

open access: yesResearch and Reports in Urology, 2021
Introduction Reports indicate many parents are negatively impacted by their child’s birth defect, experiencing feelings of anxiety, shame, and blame. These reactions have been documented for several conditions, but not hypospadias. We surveyed parents of
Phillip Snodgrass, W. Snodgrass, N. Bush
semanticscholar   +1 more source

Hypospadias

open access: yesPlastic and Reconstructive Surgery, 1966
Presentado en sesión de 12 de setiembre de ...
PATRICK CLARKSON   +2 more
openaire   +4 more sources

Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males

open access: yesEcotoxicology and Environmental Safety, 2022
Hypospadias and cryptorchidism are the most common congenital malformations in male neonates, both of which are also the important clinical manifestations of testicular dysgenesis syndrome and share a same origin.
Xiang Zhou   +11 more
doaj   +1 more source

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