Profile of Hypospadias Cases in Central Java, Indonesia [PDF]
Journal of Biomedicine and Translational Research, 2015 Background: Hypospadia is believed to be a multifactorial disease. The risk factors that may induce the formation of hypospadias are environmental factors, endocrine disruptors, and genetic factors.
Ziske Maritska +4 more
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Severity-Dependent Profile of the Metabolome in Hypospadias
Frontiers in Pediatrics, 2020 Background & Objective: Hypospadias, characterized by the displacement of the opening of the urethra at any point in the medial-ventral side of the penis, is classified upon severity as mild (Type I) and severe (Type II and Type III) hypospadias ...
Coriness Piñeyro-Ruiz +3 more
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Soft tissue reinforcement interposition flaps in hypospadias repair
Indian Journal of Plastic Surgery, 2007 Purpose: To discuss the role and mechanism of action of soft tissue reinforcement interposition flaps (strifs) in hypospadias repairs (reinforced hypospadiac urethroplasties).
R B Singh +3 more
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The spectrum of phenotypes associated with mutations in steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) includes severe penoscrotal hypospadias in 46,XY males without adrenal insufficiency [PDF]
, 2009 OBJECTIVE. Hypospadias is a frequent congenital anomaly but in most cases an underlying cause is not found. Steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) is a key regulator of human sex development and an increasing number of SF-1 (NR5A1) mutations are ...
Achermann, J.C. +9 more
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Can Testosterone Alter the Degree of Hypospadias? A Comprehensive Study
Journal of Indian Association of Pediatric Surgeons, 2021 Context: In this study, we observed using serial injections of parenteral testosterone whether we can alter the degree of hypospadias. Aims: The aim was to study the effect of testosterone on different parts of the phallus in hypospadias and to see if we
Dasmit Singh Khokar, Ravi Vadilal Patel
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Defective spermatogenesis: Martin et al. respond [PDF]
, 2008 This is an Open Access article - Copyright @ National Institute of Environmental Health Science.BACKGROUND: Male reproductive tract abnormalities such as hypospadias and cryptorchidism, and testicular cancer have been proposed to comprise a common ...
Boobis, Alan R. +5 more
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Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias: A Case–Control Study in Newborn Boys [PDF]
, 2004 Little is known on environmental risk factors for cryptorchidism and hypospadias, which are among the most frequent congenital abnormalities. The aim of our study was to identify risk factors for cryptorchidism and hypospadias, with a focus on potential ...
Alex Burdorf +8 more
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Renal Subcapsular xenografing of human fetal external genital tissue - A new model for investigating urethral development. [PDF]
, 2017 In this paper, we introduce our novel renal subcapsular xenograft model for the study of human penile urethral and clitoral development. We grafted fifteen intact fetal penes and clitorides 8-11 weeks fetal age under the renal capsules of gonadectomized ...
Baskin, Laurence +6 more
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Parental risk factors associated with hypospadias
Archives of Medicine and Health Sciences, 2013 Introduction: Hypospadias is one of the most common congenital anomalies of male external genitalia. It occurs in approximately 1 in 250 newborn. Hypospadias can be defined as an abnormal urethral orifice under surface of the penis with or without ...
Bindhu Suma Shekar, Ramakrishna Avadhani
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The “Safdarjung Method” of Estimation of Total Body Surface Area (TBSA) Burns in Major Amputees
Indian Journal of Plastic Surgery, 2020 Accurate estimation of total body surface area (TBSA) burns is the cornerstone of initiating correct fluid therapy in burns. The current formulae are designed for patients with intact body. However, the authors having worked at a high-volume burns center
Neha Chauhan +2 more
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