Results 41 to 50 of about 26,178 (244)

Genomic copy number variation association study in Caucasian patients with nonsyndromic cryptorchidism [PDF]

, 2016
Copy number variation (CNV) is a potential contributing factor to many genetic diseases. Here we investigated the potential association of CNV with nonsyndromic cryptorchidism, the most common male congenital genitourinary defect, in a Caucasian ...
Abrams, Debra J., Banihani, Ahmad H., Barthold, Julia Spencer, Chiavacci, Rosetta M., Devoto, Marcella, Figueroa, T. Ernesto, Gonzalez, Ricardo, Hagerty, Jennifer A., Hakonarson, Hakon, Harden, Kisha R., Kim, Cecilia E., Kolon, Thomas F., Li, Jin, Noh, Paul H., Olivant Fisher, Alicia, Sol Church, Katia, Stabley, Deborah, Wang, Yanping   +17 more
core   +1 more source

Modern competency‐based teaching of human sexual development

Anatomical Sciences Education, EarlyView.
Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler, Alessandro Bilella, Christian M. Hammer   +2 more
wiley   +1 more source

Prevalence of hypospadias in Italy according to severity, gestational age and birthweight: an epidemiological study

Italian Journal of Pediatrics, 2009
Background Hypospadias is a congenital displacement of the urethral meatus in male newborns, being either an isolated defect at birth or a sign of sexual development disorders.
Magnani Cinzia, Gragnani Giuseppe S, Giuffrè Mario, Gerola Orietta, Di Stefano Maria C, De Santis Luisa, Danieli Roberto, Cocchi Guido, Celandroni Amerigo, Pardi Daniela, Bertelloni Silvano, Scaramuzzo Rosa T, Ghirri Paolo, Meossi Cristiano, Merusi Ilaria, Sabatino Giuseppe, Tumini Stefano, Corsello Giovanni, Boldrini Antonio   +18 more
doaj   +1 more source

Reproductive tract biology: Of mice and men. [PDF]

, 2019
The study of male and female reproductive tract development requires expertise in two separate disciplines, developmental biology and endocrinology.
Baskin, Laurence S, Cao, Mei, Cunha, Gerald R, Ricke, Will A, Robboy, Stanley J, Sinclair, Adriane   +5 more
core  

Molecular genetics and pathophysiology of 17 beta-hydroxysteroid dehydrogenase 3 deficiency. [PDF]

, 1996
Autosomal recessive mutations in the 17 beta-hydroxysteroid dehydrogenase 3 gene impair the formation of testosterone in the fetal testis and give rise to genetic males with female external genitalia.
Andersson, Stefan, Blethen, Sandra L., Bloise, Walter, Cutler Jr., Gordon B., Davis, Daphne L., Geissler, Wayne M., Griffin, James E., Grumbach, Melvin M., Mendonca, Berenice B., New, Maria I., Russell, David D., Schwarz, Hans P., Wilson, Jean D., Witchel, Selma F., Wu, Ling   +14 more
core   +1 more source

Airway Involvement in Conradi–Hünermann–Happle Syndrome: A Novel Clinical Manifestation

The Laryngoscope, EarlyView.
We report the first documented case of airway involvement in Conradi–Hünermann–Happle syndrome (CDPX2), an X‐linked dominant form of chondrodysplasia punctata caused by pathogenic variants in EBP. A 2‐month‐old female with genetically confirmed CDPX2 developed severe subglottic stenosis and persistent respiratory distress requiring CPAP; cross ...
Enrique G. Villarreal, Jackie Chiang, Evan J. Propst, Nikolaus E. Wolter   +3 more
wiley   +1 more source

Association of abnormal placental perfusion with the risk of male hypospadias: a hospital-based retrospective cohort study

BMC Pregnancy and Childbirth, 2020
Background The effect and extent of abnormal placental perfusion (APP) on the risk of male hypospadias are poorly understood. We compared the prevalence of male hypospadias in the offspring of women with APP and quantify the extent of the APP effect on ...
Chen Zhu, Bin Zhang, Ting Peng, Ming-Qing Li, Yun-Yun Ren, Jiang-Nan Wu   +5 more
doaj   +1 more source

Intrauterine exposure to mild analgesics during pregnancy and the occurrence of cryptorchidism and hypospadia in the offspring: The Generation R Study [PDF]

, 2012
This article is available open access through the publisher’s website. Copyright @ 2012 The Authors.BACKGROUND - Recently, over-the-counter mild analgesic use during pregnancy has been suggested to influence the risk of reproductive disorders in the ...
A. Burdorf, A. Hofman, A. Kortenkamp, Anderson, Aronoff, Berkowitz, Boisen, C. A. Snijder, Chacko, de Muinck Keizer-Schrama, Dolk, E. A. P. Steegers, Foster, Greenland, Greenland, Gupta, Gupta, Hutson, Jaddoe, Jensen, Jentink, Kalfa, Kristensen, Main, Palmer, Palmlund, Pierik, Pierik, Pierik, Skakkebak, Toppari, U. Hass, V. W. V. Jaddoe, Welsh, Werler   +34 more
core   +1 more source

Perioperative Opioid Use and Risk of Persistent Use After Common Otolaryngologic Procedures

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective The objective of this study was to evaluate the incidence of perioperative opioid prescription and the development of new persistent opioid usage in patients prescribed perioperative opioids for common otolaryngological procedures. Study Design Retrospective cohort study. Setting TriNetX US Collaborative Research Network. Methods The
Michael Liu, Austin Lee, Salim Hayek, Shawn Li   +3 more
wiley   +1 more source

Tubularized incised plate and onlay island flap urethroplasty for management of fresh and recurrent hypospadias repair

Al-Azhar Assiut Medical Journal
Background and aim Hypospadias is the most prevalent congenital abnormality of the male genitalia, recurrent hypospadias is a term referrer to patients who have undergone unsuccessful attempts for hypospadias repair due to complications, and the proper ...
Mohamed M.A.A. Hamid, Hazem A.S. Deif, Emadeldeen S.A. Saleh, Mahmoud I.A.A. Baqi   +3 more
doaj   +1 more source