Results 11 to 20 of about 17,428 (209)

Toward the effective surveillance of hypospadias [PDF]

, 2004
Concern about apparent increases in the prevalence of hypospadias--a congenital male reproductive-tract abnormality--in the 1960s to 1980s and the possible connection to increasing exposures to endocrine-disrupting chemicals have underlined the ...
John E S Scott, Addor, Marie-Claude, Calzolari, Elisa, Addor, M.C., Nigel Physick, Botting, B., Loane, M, Scott, JES, Ester Garne, Elisa Calzolari, Physick, N., Stone, D, Romano Tenconi, Stone, David, Bev Botting, Dolk, H, Pierini, A, Marie-Claude Addor, Dolk, H., Pierini, Anna, Helen Dolk, Martine Vrijheid, Addor, MC, Maria Loane, Calzolari, E., Scott, J.E., Tenconi, R, Awi Wiesel, Hermien de Walle, David Stone, Garcia-Minaur, S, Physick, N, Physick, Nigel, Catherine de Vigan, Scott, John ES, de Vigan, Catherine, Garne, E., Garcia-Minaur, S., Loane, M., Pierini, A., Vrijheid, M., de Walle, H., Stone, D., Vrijheid, M, Tenconi, Romano, De, WH, Botting, Bev, Tenconi, R., Vrijheid, Martine, Wiesel, A, de Walle, Hermien, Anna Pierini, Garcia-Minaur, Sixto, Calzolari, E, Dolk, Helen, Garne, Ester, Wiesel, A., Wiesel, Awi, de, VC, de Vigan, C, de Vigan, C., de Walle, H, Garne, E, Botting, B, Sixto Garcia-Minaur, Loane, Maria   +65 more
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Hypospadias

Plastic and Reconstructive Surgery, 1966
Presentado en sesión de 12 de setiembre de ...
PATRICK CLARKSON, T. R. Broadbent, R. M. Woolf   +2 more
openaire   +4 more sources

Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males

Ecotoxicology and Environmental Safety, 2022
Hypospadias and cryptorchidism are the most common congenital malformations in male neonates, both of which are also the important clinical manifestations of testicular dysgenesis syndrome and share a same origin.
Xiang Zhou, Xu Zhang, Xuan zhou, Gulinuer Abulimiti, Yichun Wang, Qijie Zhang, Rong Cong, Chengjian Ji, Jiaochen Luan, Liangyu Yao, Jie Yang, Ninghong Song   +11 more
doaj   +1 more source

Severity-Dependent Profile of the Metabolome in Hypospadias

Frontiers in Pediatrics, 2020
Background & Objective: Hypospadias, characterized by the displacement of the opening of the urethra at any point in the medial-ventral side of the penis, is classified upon severity as mild (Type I) and severe (Type II and Type III) hypospadias ...
Coriness Piñeyro-Ruiz, Nataliya E. Chorna, Marcos Raymond Pérez-Brayfield, Juan Carlos Jorge   +3 more
doaj   +1 more source

Association between perinatal factors and hypospadias in newborns: a retrospective case–control study of 42,244 male infants

BMC Pregnancy and Childbirth, 2022
Background Hypospadias is one of the most common male congenital malformations worldwide. It is characterised by the abnormal positioning of the opening of urethra, and may lead to problems with urination and sexual function.
Yi Wang, Lin Wang, Zeyong Yang, Fang Chen, Zhiwei Liu, Zheng Tang   +5 more
doaj   +1 more source

Preoperative Hormonal Stimulation In Hypospadias: A Systematic Review

, 2023
Background: Preoperative hormonal stimulation with testosterone or estrogen is an emerging treatment modality for hypospadias, which can potentially improve surgical outcomes and reduce the risk of complications.
Indrayudha Pramono, Safendra Siregar, Jupiter Sibarani   +2 more
core   +1 more source

Can Testosterone Alter the Degree of Hypospadias? A Comprehensive Study

Journal of Indian Association of Pediatric Surgeons, 2021
Context: In this study, we observed using serial injections of parenteral testosterone whether we can alter the degree of hypospadias. Aims: The aim was to study the effect of testosterone on different parts of the phallus in hypospadias and to see if we
Dasmit Singh Khokar, Ravi Vadilal Patel
doaj   +1 more source

Profile of Hypospadias Cases in Central Java, Indonesia

Journal of Biomedicine and Translational Research, 2015
Background: Hypospadia is believed to be a multifactorial disease.  The risk factors that may induce the formation of hypospadias are environmental factors, endocrine disruptors, and genetic factors.
Ziske Maritska, Mahayu Dewi Ariani, Achmad Zulfa Juniarto, Sultana MH Faradz, Ardy Santosa   +4 more
doaj   +1 more source

Dysregulated expression of androgen metabolism genes and genetic analysis in hypospadias

Molecular Genetics & Genomic Medicine, 2020
Background The aberrant expression of genes involved in androgen metabolism and genetic contribution are unclear in hypospadias. Methods We compared gene expression profiles by RNA sequencing from five non‐hypospadiac foreskins, five mild hypospadiac ...
Zhongzhong Chen, Xiaoling Lin, Yaping Wang, Hua Xie, Fang Chen   +4 more
doaj   +1 more source

Genetic and other epidemiological risk factors of infants and children with hypospadias: a case control study

African Journal of Urology, 2023
Background To study hypospadias as regard epidemiological risk factors and genetic association with mutations in Steroid 5 alpha reductase type 2 genes.
Wafaa Moustafa, Soheir Abouelella, Maha Tawfik, Mai Abuelyazeed, Fouad Zanaty   +4 more
doaj   +1 more source