Results 71 to 80 of about 19,055 (233)

Coping styles in patients with hypospadias [PDF]

, 2019
OBJECTIVE: The objective of this study is to investigate the coping styles used by patients with hypospadias. Long-term hypospadias studies generally show satisfying outcomes, but some report a lower quality of life (QoL) or poorer psychosocial ...
van der Werf-Kok, Esther T., de Kort, Laetitia M.O., Rynja, Sybren P., de Jong, Tom P.V.M., Bosch, J. L.H.Ruud   +4 more
core   +1 more source

Variants in the Imprinted IGF2 Gene: A Review and Phasing of De Novo Variants Using Long‐Read Sequencing

Clinical Genetics, EarlyView.
Pathogenic IGF2 variants on the paternal allele can cause Silver–Russell syndrome, with highly variable growth and neurodevelopmental outcomes. Long‐read sequencing can determine the parental origin of de novo IGF2 variants via methylation patterns without parental samples, improving diagnostics for imprinted genes.
Trine Maxel Juul, Susanne Eriksen Boonen, Katja Venborg Pedersen, Caroline Hey Bækgaard, Martin Larsen, Maria Kibæk, Niels Illum, Malene Heideman, Christiane Nielsen, Emilie Boye Lester, Christina Fagerberg   +10 more
wiley   +1 more source

Clinical Characteristics of Hypospadias and Its Association with Very Low Birth Weight Infants with Small for Gestational Age [PDF]

Neonatal Medicine
Purpose To investigate the risk factors associated with hypospadias in very low birth weight (VLBW) infants (VLBWIs). Methods We retrospectively analyzed 729 infants born at ≥24 weeks of gestational age and weighing
Seon Nyo Kim, Seung Hyun Kim, Chan Kim, Hanna Kim, Jieun Hwang, Misun Yang, So Yoon Ahn, Se In Sung, Yun Sil Chang, Hyeseon Kim   +9 more
doaj   +1 more source

Outcomes of Hypospadias Surgery Performed by Different Surgeons Under the Supervision of an Experienced Pediatric Urology Surgeon

, 2019
Objective:Hypospadias is one of the most common congenital anomalies among males. Hypospadias repair is still a challenging issue due to its results and frequently seen complications.
Oktay Özman, Ozman, Oktay, Fatih Gevher, Bülent Önal, Gezer, Murat, Onal, Bulent, Murat Kuru, Kuru, Murat, Murat Gezer, GEVHER, FATİH   +9 more
core   +1 more source

Male genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas, Rory Barry, Richard E. Watchorn, Christopher B. Bunker   +3 more
wiley   +1 more source

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2350-2356, October 2026.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

Genome-wide association study in Chinese cohort identifies one novel hypospadias risk associated locus at 12q13.13

BMC Medical Genomics, 2019
Background Hypospadias risk–associated gene variants have been reported in populations of European descent using genome-wide association studies (GWASs).
Zhongzhong Chen, Xiaoling Lin, Yunping Lei, Haitao Chen, Richard H. Finnell, Yaping Wang, Jianfeng Xu, Daru Lu, Hua Xie, Fang Chen   +9 more
doaj   +1 more source

Unusual complication of prolonged indwelling urinary catheter - iatrogenic hypospadias

Journal of Family Medicine and Primary Care, 2016
Long-time urethral catheterization may be responsible for various complications such as urethral stricture, urethral fracture, urinary tract infections, and hypospadias.
Gunjan Garg, Vishal Baghele, Naveen Chawla, Atul Gogia, Atul Kakar   +4 more
doaj   +1 more source

Hypospadias [PDF]

, 1964
The known literature on hypospadias largely concerns the treatment of this anomaly, and the related disturbances in wound healing. The morphology of this anomaly and the factors underlying a disturbance in wound healing, however, receive comparatively ...
Meulen, J.C.H.M. (Jacques) van der
core   +1 more source

Pharmacokinetics of Intravenous Melatonin in Preschool‐Aged Pediatric Surgical Patients

Pediatric Anesthesia, Volume 36, Issue 10, Page 1308-1315, October 2026.
ABSTRACT Background Melatonin may have several beneficial clinical effects in the perioperative setting. In children, it has been studied for preoperative anxiety, postoperative pain, and emergence delirium. Melatonin's pharmacokinetic profile is well‐known in adults, but data in young children are sparse.
Anne Louise de Barros Garioud, Arash Afshari, Lau Romlund Halgreen, Kristian Østergaard Nielsen, Lars Peter Kloster Andersen   +4 more
wiley   +1 more source