Results 41 to 50 of about 1,450 (179)
Asplenia and spleen hypofunction
Asplenia (the congenital or acquired absence of the spleen) and hyposplenism (defective spleen function) are common causes of morbidity and mortality. The spleen is a secondary lymphoid organ that is responsible for the regulation of immune responses and
Luu, Sarah +10 more
core +2 more sources
Grave's disease and acquired hyposplenism [PDF]
A 38-year-old Caucasian woman was referred to the hematology clinic for unexplained leukocytosis and thrombocytosis and ‘possible myeloproliferative disorder’. Her history included only Grave's disease (GD) in remission for 2 years after methimazole treatment.
A, Klepfish, Y, Halperin, Ami, Schattner
openaire +2 more sources
Gain-of-function (GOF) mutations in STIM1 are responsible for tubular aggregate myopathy and Stormorken syndrome (TAM/STRMK), a clinically overlapping multisystemic disease characterised by muscle weakness, miosis, thrombocytopaenia, hyposplenism ...
Eduardo de la Fuente-Munoz +17 more
doaj +1 more source
Crohn’s disease (CD), as one of the principal form of inflammatory bowel disease (IBD), is characterized by the chronic and recurring inflammatory conditions in the intestine resulting from the over-activation of intestinal immunity.
Dan Pu +5 more
doaj +1 more source
Naganishia diffluens, a rare non‐neoformans cryptococcal species, was identified by PCR sequencing as the causative agent of oral cryptococcosis in a 31‐year‐old Iranian man with β‐thalassemia. This case represents the first documented instance of oral infection by N.
Zahra Yahyazadeh +13 more
wiley +1 more source
Attenuation of Autoimmune Phenomena in a Patient with Autoimmune Polyglandular Syndrome Type 1
Autoimmune polyglandular syndrome type 1 (APS1) is a progressive life-threatening illness with no known cure. Current treatments involve replacement of the hormone deficiencies that result from autoimmune destruction of multiple endocrine organs.
Jill D. Jacobson +3 more
doaj +1 more source
ABSTRACT Background and Aims Sickle cell disease is a genetic disorder whose pathophysiology is primarily characterized by vasoocclusive crises and hemolytic crises. The stationary phase describes the interval between two vasoocclusive crises. The aim of this systematic review and meta‐analysis was to synthesize studies published over the past two ...
Josué Louokdom Simo +5 more
wiley +1 more source
ABSTRACT Introduction Since the publication of the first European Society for the Study of Coeliac Disease (ESsCD) guidelines in 2019, substantial advances have been made in understanding the management and complex disease courses of coeliac disease (CeD) in adults.
Abdulbaqi Al‐Toma +20 more
wiley +1 more source
Initial modelling and updates on cost effectiveness from the first 10 years of a spleen registry
Objective: To validate our estimates from our original model and re‐evaluate the cost‐effectiveness of Spleen Australia, the Australian post‐splenectomy registry, using our original model with updated model parameters based on advances in the literature ...
Sarah Luu +4 more
doaj +1 more source
Hyposplenism in gastro-intestinal disease [PDF]
The hazards of living without a spleen were recognised by the paediatricians in the early 1960’s when they focussed attention on the syndrome of fulminant sepsis, often due to pneumococcal infection, occurring in young children within the first two years
Toghill, P. J., Muller, Andre F.
core

