Results 141 to 150 of about 135,663 (215)

Blood flow restriction: The acute effects of body tilting and reduced gravity analogues on limb occlusion pressure

Experimental Physiology, EarlyView.
Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley   +1 more source

A therapeutic challenge relating to the association of orthostatic hypotension and supine hypertension in a patient with cardiac autonomic neuropathy: a case report

Journal of Medical Case Reports
Background Cardiac autonomic neuropathy is a highly prevalent pathology in the diabetic population, and is the leading cause of death in this population. Orthostatic hypotension is the main clinical manifestation of the disease.
Jama Dounia, Haless Kamal, Selmaoui Marouane, Haboub Meryem, Habbal Rachida, Drighil Abdenasser, Azzouzi Leila   +6 more
doaj   +1 more source

Assessing High-Order Links in Cardiovascular and Respiratory Networks via Static and Dynamic Information Measures [PDF]

arXiv
The network representation is becoming increasingly popular for the description of cardiovascular interactions based on the analysis of multiple simultaneously collected variables. However, the traditional methods to assess network links based on pairwise interaction measures cannot reveal high-order effects involving more than two nodes, and are not ...
arxiv  

Vascular health and exercise in females throughout the lifespan: Exploring puberty, pregnancy and menopause

Experimental Physiology, EarlyView.
Abstract This narrative review highlights the impact of exercise on vascular health in females over the lifespan with an emphasis on puberty, pregnancy and menopause. These events encompass substantial changes in sex hormone levels, particularly oestrogens and progesterone.
Kathleen B. Miller, M. Erin Moir, Brandon G. Fico   +2 more
wiley   +1 more source

Study protocol for the Heads-Up trial: a phase II randomized controlled trial investigating head-up tilt sleeping to alleviate orthostatic intolerance in Parkinson’s Disease and parkinsonism

BMC Neurology
Background In persons with Parkinson’s Disease (PD) or certain forms of atypical parkinsonism, orthostatic hypotension is common and disabling, yet often underrecognized and undertreated.
Amber H. van der Stam, Nienke M. de Vries, Sharon Shmuely, Daan Smeenk, Joost H. Rutten, Ineke A. van Rossum, Susanne T. de Bot, Jurgen A. Claassen, Bastiaan R. Bloem, Roland D. Thijs   +9 more
doaj   +1 more source

Plasticity of the heart in response to changes in physical activity

The Journal of Physiology, EarlyView.
Abstract figure legend The heart adapts to changes in physical activity, with inactivity (e.g. bed rest or spaceflight) causing cardiac atrophy and ventricular stiffening, and endurance exercise training leading to eccentric hypertrophy and improved ventricular compliance.
Eric T. Hedge, Tiffany L. Brazile, Richard L. Hughson, Benjamin D. Levine   +3 more
wiley   +1 more source

α‐Synuclein in Parkinson's Disease: From Bench to Bedside

Medicinal Research Reviews, Volume 45, Issue 3, Page 909-946, May 2025.
ABSTRACT α‐Synuclein (α‐syn), a pathological hallmark of PD, is emerging as a bridging element at the crossroads between neuro/immune‐inflammatory responses and neurodegeneration in PD. Several evidence show that pathological α‐syn accumulates in neuronal and non‐neuronal cells (i.e., neurons, microglia, macrophages, skin cells, and intestinal cells ...
Gabriele Bellini, Vanessa D'Antongiovanni, Giovanni Palermo, Luca Antonioli, Matteo Fornai, Roberto Ceravolo, Nunzia Bernardini, Pascal Derkinderen, Carolina Pellegrini   +8 more
wiley   +1 more source

Orthostatic hypotension, orthostatic intolerance and frailty: The Irish Longitudinal Study on Aging-TILDA.

Archives of gerontology and geriatrics (Print), 2015
M. O’Connell, G. Savva, C. Fan, R. Kenny   +3 more
semanticscholar   +1 more source

Lactate orchestrates metabolic hemodynamic adaptations through a unique combination of venocontraction, artery relaxation, and positive inotropy

Acta Physiologica, Volume 241, Issue 5, May 2025.
Abstract Aim H+ facilitates metabolic blood flow regulation while negatively impacting cardiac contractility. Cardiovascular consequences of conjugate bases accumulating alongside H+ remain unclear. Here, we evaluate the cardiovascular effects of nine prominent carboxylates—particularly lactate, 3‐hydroxybutyrate, and butyrate—linked to metabolic and ...
Casper Homilius, Jacob M. Seefeldt, Jakob Hansen, Roni Nielsen, Frank V. de Paoli, Ebbe Boedtkjer   +5 more
wiley   +1 more source

Machine Learning Predicts Risk of Falls in Parkison's Disease Patients in a Multicenter Observational Study

European Journal of Neurology, Volume 32, Issue 5, May 2025.
ABSTRACT Background Postural instability and gait difficulties are key symptoms of Parkinson's disease (PD), elevating the risk of falls substantially. Falls afflict 35% to 90% of PD patients, representing a major challenge in managing the condition. Accurate prediction of fall risk and identification of contributing factors are essential for timely ...
Maria Chiara Malaguti, Chiara Longo, Monica Moroni, Flavio Ragni, Stefano Bovo, Marco Chierici, Lorenzo Gios, Laura Avanzino, Roberta Marchese, Francesca Di Biasio, Matteo Pardini, Denise Cerne, Paola Mandich, Manuela Marenco, Antonio Uccelli, Bruno Giometto, Giuseppe Jurman, Venet Osmani, the NeuroArtP3 Network, Andrea Falini, Antonella Castellano, Andrea Rossi, Domenico Tortora, Costanza Parodi, Antonio Verrico, Federica Sabatini, Emilio Portaccio, Matteo Betti, Guido Pasquini, Filippo Gerli, Claudia Niccolai, Isabella Cama, Cristina Campi, Alessio Cirone, Sara Garbarino, Michele Piana, Donatella Ottaviani, Raffaella Di Giacopo, Ruggero Bacchin   +38 more
wiley   +1 more source