Results 151 to 160 of about 78,000 (283)

Cardiovascular reserve as an integrative physiological construct: Current evidence, emerging technologies and future directions

Clinical Physiology and Functional Imaging, Volume 46, Issue 6, November 2026.
Abstract Cardiovascular reserve represents the integrated physiological capacity of the cardiovascular system to maintain tissue perfusion during increasing physiological stress. Although reserve has long been recognized conceptually, its direct assessment remains challenging.
Uri Gabbay, Shai Fein, Michael J. Drescher   +2 more
wiley   +1 more source

Relationship between orthostatic hypotension, internal carotid artery blood flow, and cognition in patients with cervical spinal cord injury. [PDF]

Front Neurol
Lee JJ, Joo MC.
europepmc   +1 more source

A Phase 1 Study of MK‐1942, a Negative Allosteric Modulator of mGluR2, in Healthy Japanese to Flexibly Assess Factors Including CYP2C19 Phenotype

Clinical and Translational Science, Volume 19, Issue 11, November 2026.
ABSTRACT MK‐1942 is a negative allosteric modulator of the metabotropic glutamate receptor 2 that was investigated for the treatment of Alzheimer's disease and depression. Nonclinical studies with recombinant human CYPs and genotyped human hepatocytes suggested that CYP2C19 is involved in the metabolism of MK‐1942. Given the high incidence of different
Chihiro Hasegawa, Yohei Doi, Tomona Hirano, Masayoshi Shirakawa, Saori Tsuchiya, Hiroyuki Yoshitsugu, Kenichi Furihata, Callie Miller, Sonal Singh, Tamara Cabalu, Ka Lai Yee, Tjerk Bueters, Zoi Alexopoulou   +12 more
wiley   +1 more source

Unmasking orthostatic hypotension after cellular therapy: risk factors, implications, and clinical significance. [PDF]

Support Care Cancer
Vazquez-Urrutia JR, Santucci J, Modgil P, Lal A, Inoue Y, Zimmerman J, Woodworth R, Knol K, Hess E, Jordan J, Stover J, Rekawek E, Cioccio J, Rakszawski K, Songdej N, Nickolich M, Zheng H, Naik S, Ehmann C, Silar B, Vajdic C, Bartram D, Mineish S, Minagawa K.   +23 more
europepmc   +1 more source

Cardiorenal Mortality and Safety Outcomes of GLP‐1 Receptor Agonists in Type 2 Diabetes With BMI Below 27 kg/m2: A Target Trial Emulation

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10498-10512, November 2026.
ABSTRACT Aims Cardiorenal evidence for glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) derives mainly from trials in overweight or obesity; data in adults with Type 2 diabetes (T2D) and body mass index (BMI) below 27 kg/m2 are limited. Materials and Methods We emulated a target trial in the TriNetX US Collaborative Network (index dates 2020 to ...
Shao‐Chia Chen, Yu‐Nan Huang, Pei‐Yun Li, Jo‐Ching Chen, Gideon Meyerowitz‐Katz, Shun‐Fa Yang, Pen‐Hua Su   +6 more
wiley   +1 more source

A deeper dip? Hot‐water immersion and nocturnal blood pressure regulation

Experimental Physiology, EarlyView.
Brendon H. Roxburgh, Kate N. Thomas
wiley   +1 more source

Light Chain Monoclonal Gammopathy of Undetermined Significance: Diagnosis, Biology, and Clinical Management

European Journal of Haematology, Volume 117, Issue 5, Page 1159-1167, November 2026.
ABSTRACT Light chain monoclonal gammopathy of undetermined significance (LC‐MGUS) is defined by an abnormal serum free light chain ratio and elevated involved light chain in the absence of a detectable immunoglobulin heavy chain on immunofixation and of end‐organ damage attributable to a plasma cell disorder.
Sigurður Yngvi Kristinsson, Thórir Einarsson Long, Sigrún Thorsteinsdóttir   +2 more
wiley   +1 more source

Improved outcomes for patients with autonomic movement disorders originally evaluated for psychogenic non-epileptiform spells. [PDF]

Front Neurol
Khoo A, Paul M, Rady N, Sunda M, Brik J, Vaou O, Hohler A.   +6 more
europepmc   +1 more source

Blood Flow Restriction Training in Stroke Rehabilitation: A Narrative Review of Current Evidence and Future Directions

Brain and Behavior, Volume 16, Issue 10, October 2026.
ABSTRACT Background Post‐stroke motor deficits cause disability, while paresis and comorbidities may limit high‐intensity training. Blood flow restriction training (BFRT) combines low‐intensity exercise with partial vascular occlusion and may promote neuromuscular adaptations at low loads.
Jiawei Tong, Lei Song, Juan Jin, Fangfang Li, Tao Huang, Hang Ying, Jiawei Zhu, Jue Wang, Jie Zhuang   +8 more
wiley   +1 more source

Coexisting Postural Orthostatic Tachycardia Syndrome on Autonomic Reflex Testing in Functional Neurologic Disorder. [PDF]

Am J Case Rep
Das S, Yerraballa SRN, Shekhawat P.
europepmc   +1 more source