Results 141 to 150 of about 27,108 (253)

Cutaneous alpha-synuclein deposition informs autonomic function in individuals with early-stage multiple system atrophy. [PDF]

open access: yesClin Auton Res
Trujillo P   +9 more
europepmc   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

open access: yesMovement Disorders Clinical Practice, Volume 13, Issue 9, Page 2081-2092, September 2026.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz   +2 more
wiley   +1 more source

Imaging patterns and genetic associations of brain atrophy across distinct symptom stages in Parkinson's disease

open access: yesNeuroprotection, Volume 4, Issue 3, Page 262-274, September 2026.
Early disease stages showed limited cortical atrophy and enrichment of synaptic and calcium signaling pathways, whereas advanced stages demonstrated widespread cortical degeneration associated with immune activation and extracellular matrix remodeling.
Yi Ji   +6 more
wiley   +1 more source

Mechanism-Based Therapy With Ampreloxetine for Neurogenic Orthostatic Hypotension in Multiple System Atrophy: A Randomized Withdrawal Trial. [PDF]

open access: yesNeurology
Freeman R   +8 more
europepmc   +1 more source

Is Aripiprazole an Effective Adjunct to Reduce Metabolic Adverse Effects Caused by Clozapine in Patients With Schizophrenia—A Systematic Review

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
Adjunctive aripiprazole may provide modest improvements in lipid parameters and body weight in clozapine‐treated patients with schizophrenia, but evidence for glucose and waist circumference outcomes remains limited. Larger, long‐term randomized controlled trials are needed.
Avtaar Singh, Soban Sadiq
wiley   +1 more source

Integrating Conventional and Emerging Approaches in Cardiovascular Risk Assessment and Management

open access: yesPublic Health Challenges, Volume 5, Issue 3, September 2026.
Conventional risk factors (hypertension, dyslipidaemia, diabetes, smoking, obesity and physical inactivity) account for roughly 70% of population‐attributable cardiovascular risk and anchor a proposed three‐tier pathway: universal low‐cost assessment (Tier 1), selective testing such as hsCRP or PRS where it would change management (Tier 2) and resource‐
Sana Rasheed   +4 more
wiley   +1 more source

Postural orthostatic tachycardia syndrome in adolescents with ME/CFS - a case control study. [PDF]

open access: yesFront Pediatr
Leone A   +6 more
europepmc   +1 more source

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