Results 141 to 150 of about 78,000 (283)

Orthostatic Hypotension and Falls [PDF]

Journal of the American Geriatrics Society, 2017
openaire   +2 more sources

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 4003-4016, November 2026.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

Physical Manoeuvres to Prevent Vasovagal Syncope and Initial Orthostatic Hypotension

, 2007
Vasovagal syncope ("the common faint") and near syncope from initial orthostatic hypotension are huge medical problems given the number of patients and their impact on quality of life. The treatment options are often unsatisfactory.
Krediet, Paul
core  

Diabetic Autonomic Neuropathy and Impaired Inflammatory Reflex

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
The cholinergic anti‐inflammatory pathway under normal and diabetic conditions. In the normal state, vagal activation through nicotinic acetylcholine receptors helps regulate immune responses and suppress excessive inflammation. In diabetes, impaired autonomic function and dysregulated cholinergic signalling weaken this anti‐inflammatory pathway ...
Narges Dastmalchi, Mohammad Amin Doustvandi, Reza Rahbarghazi, Khalil Hajiasgharzadeh   +3 more
wiley   +1 more source

Drug Therapy for Managing Primary Orthostatic Hypotension

, 2017
Primary orthostatic hypotension is a condition that is overlooked and undertreated. It is clinically defined as a decrease of 20 mm Hg in systolic or 10 mm Hg in diastolic BP within 3 minutes of standing. Primary orthostatic hypotension (OH) symptoms are
Hale, Genevieve M
core  

Capsulotomy With Supine Nd:YAG Laser in Children

Lasers in Surgery and Medicine, Volume 58, Issue 9, Page 772-777, November 2026.
ABSTRACT Objectives To evaluate the visual outcomes of Nd:YAG laser posterior capsulotomy performed in the supine position under general anesthesia in children with visual axis opacification after cataract surgery. Materials and Methods A retrospective clinical case series of 13 eyes of 9 children with visual axis opacification following congenital ...
Nike Klun, Manca Tekavčič Pompe
wiley   +1 more source

Orthostatic hypotension, orthostatic hypertension, and ambulatory blood pressure in patients with chronic kidney disease in CRIC. [PDF]

J Hypertens
Ghazi L, Cohen JB, Townsend RR, Drawz PE, Rahman M, Pradhan N, Cohen DL, Weir MR, Rincon-Choles H, Juraschek SP.   +9 more
europepmc   +1 more source

Uncontrolled hypertension and orthostatic hypotension in relation to standing balance in elderly hypertensive patients

, 2015
Shanshan Shen,1 Ting He,1 Jiaojiao Chu,1 Jin He,2 Xujiao Chen1 1Department of Geriatrics, Zhejiang Hospital, Hangzhou, 2Department of Neurology, Fuyuan Hospital of Yiwu, Jinhua, People’s Republic of China Objective: To investigate the ...
He T, Chu JJ, He J, Shen SS, Chen XJ
core  

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He, Jingjing Zeng, Guoqing Wang, Yuxin Li, Feng Zhang   +4 more
wiley   +1 more source

Diabetic Polyneuropathy Patients Exhibit an Altered Skeletal Muscle Proteome Phenotype

PROTEOMICS – Clinical Applications, Volume 20, Issue 6, November 2026.
ABSTRACT Purpose Diabetic polyneuropathy (DPN) is a debilitating complication of diabetes that affects motor nerves and may impair skeletal muscle health. This study investigated skeletal muscle proteomic alterations associated with DPN compared with type 2 diabetes without DPN (T2D) and healthy controls (CON).
Frederik Forsberg Thybo, Karolina Snopek Khan, Jesper Emil Jakobsgaard, Henning Andersen, Kristian Vissing, Johan Palmfeldt   +5 more
wiley   +1 more source