Results 41 to 50 of about 135,663 (215)
Identifying Decision Points for Safe and Interpretable Reinforcement Learning in Hypotension Treatment [PDF]
Many batch RL health applications first discretize time into fixed intervals. However, this discretization both loses resolution and forces a policy computation at each (potentially fine) interval. In this work, we develop a novel framework to compress continuous trajectories into a few, interpretable decision points --places where the batch data ...
arxiv
Abstract Background and purpose Treatment of freezing of gait (FoG) and other Parkinson disease (PD) axial symptoms is challenging. Systematic assessments of axial symptoms at progressively increasing levodopa doses are lacking. We sought to analyze the resistance to high levodopa doses of FoG, posture, speech, and altered gait features presenting in ...
Gabriele Imbalzano+13 more
wiley +1 more source
Postural Orthostatic Tachycardia Syndrome explained using abaroreflex response model [PDF]
Recent studies have shown that Postural Orthostatic Tachycardia Syndrome (POTS) patients have abnormal low frequency $\approx 0.1$ Hz blood pressure and heart rate dynamics. These dynamics are attributed to the baroreflex and can give insight into the mechanistic causes which are the basis for proposed subgroups of POTS.
arxiv
Objectives To assess the frequency of transient orthostatic hypotension (tOH) and its clinical impact in Parkinson disease (PD), we retrospectively studied 173 patients with PD and 173 age- and sex-matched controls with orthostatic intolerance, who ...
A. Fanciulli+12 more
semanticscholar +1 more source
Cerebrospinal fluid (CSF) alterations indicative of infratentorial superficial siderosis are prevalent amongst patients with SIH. It is speculated that a preclinical phase without symptoms or imaging signs but during which elevated biomarkers of the disease are apparent from CSF analysis might exist.
Levin Häni+7 more
wiley +1 more source
Squamous Carcinoma of the Lung Presenting as Migraine-Type Headache: A Case Report
Introduction: Orthostatic hypotension has long been recognised as a paraneoplastic effect of lung cancer. Lung cancer presenting with orthostatic hypotension and migraine-type headaches has not been previously described in the literature.
Eswaran Waran
doaj +1 more source
The management of orthostatic hypotension in Parkinson's disease
Orthostatic hypotension is a common and disabling symptom affecting Parkinson’s disease (PD) patients. We present the effect of the different therapies commonly used to manage Parkinson’s disease on this clinical manifestation.
Alvaro eSanchez-Ferro+2 more
doaj +1 more source
Orthostatic hypotension: An overlooked but clinically decisive entity
Orthostatic hypotension (OH) is defined as a drop of >20 mm Hg of systolic or >10 mm Hg of diastolic blood pressure (BP) within 3 min of standing from lying position. It is a common geriatric syndrome caused by impaired orthostatic response of BP.
Gunja Jain+3 more
doaj +1 more source
Abstract Small fiber neuropathy usually presents with gradual and progressive chronic length‐dependent pain. Acute small fiber neuropathy is rarely reported. Three patients with acute onset neuropathic pain after Oxford‐AstraZeneca ChAdOx1‐S vaccination are described.
Molly G. Abbott+10 more
wiley +1 more source
Orthostatic Hypotension: A Prodromal Marker of Parkinson's Disease?
Orthostatic hypotension is common in patients with Parkinson's disease (PD). However, it remains unknown whether orthostatic hypotension is a marker of prodromal PD or more advanced disease. The objectives of this study were to assess whether orthostatic
L. Dommershuijsen+5 more
semanticscholar +1 more source