Results 41 to 50 of about 135,663 (215)

Identifying Decision Points for Safe and Interpretable Reinforcement Learning in Hypotension Treatment [PDF]

open access: yesarXiv, 2021
Many batch RL health applications first discretize time into fixed intervals. However, this discretization both loses resolution and forces a policy computation at each (potentially fine) interval. In this work, we develop a novel framework to compress continuous trajectories into a few, interpretable decision points --places where the batch data ...
arxiv  

How resistant are levodopa‐resistant axial symptoms? Response of freezing, posture, and voice to increasing levodopa intestinal infusion rates in Parkinson disease

open access: yesEuropean Journal of Neurology, Volume 30, Issue 1, Page 96-106, January 2023., 2023
Abstract Background and purpose Treatment of freezing of gait (FoG) and other Parkinson disease (PD) axial symptoms is challenging. Systematic assessments of axial symptoms at progressively increasing levodopa doses are lacking. We sought to analyze the resistance to high levodopa doses of FoG, posture, speech, and altered gait features presenting in ...
Gabriele Imbalzano   +13 more
wiley   +1 more source

Postural Orthostatic Tachycardia Syndrome explained using abaroreflex response model [PDF]

open access: yesarXiv, 2021
Recent studies have shown that Postural Orthostatic Tachycardia Syndrome (POTS) patients have abnormal low frequency $\approx 0.1$ Hz blood pressure and heart rate dynamics. These dynamics are attributed to the baroreflex and can give insight into the mechanistic causes which are the basis for proposed subgroups of POTS.
arxiv  

Association of transient orthostatic hypotension with falls and syncope in patients with Parkinson disease

open access: yesNeurology, 2020
Objectives To assess the frequency of transient orthostatic hypotension (tOH) and its clinical impact in Parkinson disease (PD), we retrospectively studied 173 patients with PD and 173 age- and sex-matched controls with orthostatic intolerance, who ...
A. Fanciulli   +12 more
semanticscholar   +1 more source

Cerebrospinal fluid biomarkers of superficial siderosis in patients with spontaneous intracranial hypotension

open access: yesEuropean Journal of Neurology, Volume 30, Issue 1, Page 235-240, January 2023., 2023
Cerebrospinal fluid (CSF) alterations indicative of infratentorial superficial siderosis are prevalent amongst patients with SIH. It is speculated that a preclinical phase without symptoms or imaging signs but during which elevated biomarkers of the disease are apparent from CSF analysis might exist.
Levin Häni   +7 more
wiley   +1 more source

Squamous Carcinoma of the Lung Presenting as Migraine-Type Headache: A Case Report

open access: yesCase Reports in Oncology, 2015
Introduction: Orthostatic hypotension has long been recognised as a paraneoplastic effect of lung cancer. Lung cancer presenting with orthostatic hypotension and migraine-type headaches has not been previously described in the literature.
Eswaran Waran
doaj   +1 more source

The management of orthostatic hypotension in Parkinson's disease

open access: yesFrontiers in Neurology, 2013
Orthostatic hypotension is a common and disabling symptom affecting Parkinson’s disease (PD) patients. We present the effect of the different therapies commonly used to manage Parkinson’s disease on this clinical manifestation.
Alvaro eSanchez-Ferro   +2 more
doaj   +1 more source

Orthostatic hypotension: An overlooked but clinically decisive entity

open access: yesJournal of the Indian Academy of Geriatrics, 2022
Orthostatic hypotension (OH) is defined as a drop of >20 mm Hg of systolic or >10 mm Hg of diastolic blood pressure (BP) within 3 min of standing from lying position. It is a common geriatric syndrome caused by impaired orthostatic response of BP.
Gunja Jain   +3 more
doaj   +1 more source

Acute small fiber neuropathy after Oxford‐AstraZeneca ChAdOx1‐S vaccination: A report of three cases and review of the literature

open access: yesJournal of the Peripheral Nervous System, Volume 27, Issue 4, Page 325-329, December 2022., 2022
Abstract Small fiber neuropathy usually presents with gradual and progressive chronic length‐dependent pain. Acute small fiber neuropathy is rarely reported. Three patients with acute onset neuropathic pain after Oxford‐AstraZeneca ChAdOx1‐S vaccination are described.
Molly G. Abbott   +10 more
wiley   +1 more source

Orthostatic Hypotension: A Prodromal Marker of Parkinson's Disease?

open access: yesMovement Disorders, 2020
Orthostatic hypotension is common in patients with Parkinson's disease (PD). However, it remains unknown whether orthostatic hypotension is a marker of prodromal PD or more advanced disease. The objectives of this study were to assess whether orthostatic
L. Dommershuijsen   +5 more
semanticscholar   +1 more source

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