Results 71 to 80 of about 136,879 (260)

Investigating Dopamine Replacement–Associated Fluctuations in Cognition and Mood in Cognitively Unimpaired Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor fluctuations, characterized by variability in mood and cognition, are prevalent in advanced Parkinson's disease (PD), but less is known about these fluctuations in early PD. Objective The objective was to characterize fluctuations in cognition and mood in early PD without cognitive impairment.
Abhimanyu Mahajan, Christopher B. Morrow, Joseph Seemiller, Kelly A. Mills, Gregory M. Pontone   +4 more
wiley   +1 more source

Relationships between orthostatic hypotension, frailty, falling and mortality in elderly care home residents

BMC Geriatrics, 2019
BackgroundOrthostatic hypotension (OH; profound falls in blood pressure when upright) is a common deficit that increases in incidence with age, and may be associated with falling risk.
B. Shaw, Dave Borrel, Kimiya Sabbaghan, C. Kum, Yijian Yang, S. Robinovitch, V. Claydon   +6 more
semanticscholar   +1 more source

Cardiorespiratory Response to Exercise in Parkinson's Disease: Associations with Autonomic Dysfunction and Physical Activity

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Both autonomic dysfunction and low levels of physical activity could contribute to reduced cardiorespiratory fitness in people with Parkinson's disease (PD). However, the interrelationship between these concepts is not well understood.
Kars I. Veldkamp, Sabine Schootemeijer, Hilde Joosten, Bastiaan R. Bloem, Luc J.W. Evers, Nienke M. de Vries   +5 more
wiley   +1 more source

Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Parkinson's Disease: Results from a Phase II Randomized Control Trial (STRIPE)

Movement Disorders, EarlyView.
Abstract Background Lower urinary tract symptoms (LUTS) are common Parkinson's disease (PD), causing great impact. Objective The goal was to undertake a phase II randomized control trial of transcutaneous tibial nerve stimulation (TTNS) delivered by Geko device for LUTS related to overactive bladder (OAB) in PD, an easy to use of the shelf solution ...
Matthew D. Smith, Gabriella E. Portlock, Anisha Cullen, Anahita Nodehi, Marcus J. Drake, Yoav Ben‐Shlomo, Emily J. Henderson   +6 more
wiley   +1 more source

Frequency Distribution of Orthostatic Hypotension, Nocturnal Hypertension, and Postprandial Hypotension in Patients with Parkinson's Disease: A Case- Control Study

مجله دانشکده پزشکی اصفهان, 2012
Background: Orthostatic hypotension is a common autonomic dysfunction in Parkinson's disease. Major hypotheses proposed in the etiology of orthostatic hypotension include sympathetic denervation and treatment with dopaminergic drugs.
Ahmad Chitsaz, Mohammad Saadatnia, Maliheh Khalili Bandali   +2 more
doaj  

Treatment Selection and Prioritization for the EJS ACT‐PD MAMS Trial Platform

Movement Disorders, EarlyView.
Abstract Background There are currently no disease‐modifying therapies (DMTs) registered for Parkinson's disease (PD). The Edmond J. Safra Accelerating Clinical Trials in Parkinson Disease (EJS ACT‐PD) initiative will expedite clinical assessment of putative DMTs through a multi‐arm multistage (MAMS) trial, testing several treatments against a common ...
Cristina Gonzalez‐Robles, Dilan Athauda, Thomas R. Barber, Roger A. Barker, David T. Dexter, Susan Duty, Romy Ellis‐Doyle, Sonia Gandhi, Joel Handley, Edwin Jabbari, Keith Martin, Kevin McFarthing, Georgia Mills, Heather Mortiboys, Stephen Mullin, Rebecca Petty, Esther Sammler, Paula Scurfield, Simon R.W. Stott, George K. Tofaris, Li Wei, Caroline H. Williams‐Gray, Alan Wong, Marie‐Louise Zeissler, Richard K. Wyse, Camille B. Carroll, Thomas Foltynie, Oliver Bandmann, Anthony H.V. Schapira, on behalf of the EJS ACT‐PD Consortium   +29 more
wiley   +1 more source

The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes

Acta Medica Indonesiana, 2016
Aim: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. Methods: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60 years old who ...
Catarina Budyono, Siti Setiati, Dyah Purnamasari, Cleopas M Rumende   +3 more
doaj  

Vitamin D and orthostatic hypotension [PDF]

Age and Ageing, 2012
we aimed to investigate on the potential relationship between vitamin D and orthostatic hypotension (OH) in a case-control model in older adults.all participants were community-dwelling adults who were not taking vitamin D supplements. Cases were subjects aged 64 or older who were diagnosed with OH at a Falls and Blackout Unit.
Kevin McCarroll, Conal Cunningham, Rose Anne Kenny, Martin Healy, David Robinson, Avril Coughlan   +5 more
openaire   +5 more sources

Orthostatic hypotension in hereditary transthyretin amyloidosis: epidemiology, diagnosis and management

Clinical Autonomic Research, 2019
Neurogenic orthostatic hypotension is a prominent and disabling manifestation of autonomic dysfunction in patients with hereditary transthyretin (TTR) amyloidosis affecting an estimated 40–60% of patients, and reducing their quality of life.
J. Palma, A. González-Duarte, H. Kaufmann   +2 more
semanticscholar   +1 more source

Distinct Longitudinal Clinical‐Neuroanatomical Trajectories in Parkinson's Disease Clinical Subtypes: Insight toward Precision Medicine

Movement Disorders, EarlyView.
ABSTRACT Background Parkinson's disease (PD) varies widely across individuals in clinical manifestations and course of progression. Identification of distinct biological subtypes could explain this heterogeneity, identify its pathophysiology, and predict disease progression. Objectives Our aim was to compare longitudinal clinical trajectories and brain
Seyed‐Mohammad Fereshtehnejad, Roqaie Moqadam, Houman Azizi, Ronald B. Postuma, Mahsa Dadar, Anthony E. Lang, Connie Marras, Yashar Zeighami   +7 more
wiley   +1 more source