Results 121 to 130 of about 279,014 (316)

Neurogenic orthostatic hypotension – management update and role of droxidopa

, 2015
Joy Vijayan,1 Vijay K Sharma1,21Department of Medicine, Division of Neurology, National University Health System, 2Yong Loo Lin School of Medicine, National University of Singapore, SingaporeAbstract: Orthostatic hypotension (OH) is defined as a ...
Sharma VK, Vijayan J
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Increased pain sensitivity in low blood pressure. [PDF]

, 2008
. There is broad evidence for a functional interaction between the cardiovascular and pain regulatory systems. One result of this interaction is the reduced sensitivity to acute pain in individuals with elevated blood pressure, which has been established
Duschek, Stefan, R. Sch, Schandry, Rainer, W. Schwarzkopf, S. Duschek, Schwarzkopf, W.   +5 more
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Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Orthostatic hypotension and survival.

, 2013
In this Kaplan-Meyer curve we wanted to test if persistent orthostatic hypotension affected survival. Concurrent manifestations of autonomic dysfunction (constipation and urinary incontinence) were not taken into consideration. The black line (group 4∶1)
Dag Aarsland (157629), Elisabet Londos (304688), Lennart Minthon (233859), Kajsa Stubendorff (304687)   +3 more
core   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

Effects of exercise intensity on postexercise hypotension after resistance training session in overweight hypertensive patients

, 2015
Paula Andréa M Cavalcante,1,2 Roberta L Rica,1,2 Alexandre L Evangelista,1,3 Andrey J Serra,3,4 Aylton Figueira Jr,1,2 Francisco Luciano Pontes Jr,5 Lon Kilgore,6 Julien S Baker,6 Danilo S Bocalini1,2 1Translational Physiology Laboratory ...
Evangelista AL, Pontes Jr FL, Cavalcante PAM, Baker JS, Figueira Jr A, Serra AJ, Kilgore L, Rica RL, Bocalini DS   +8 more
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Adenosine and dialysis hypotension

, 2006
In this issue, Imai et al. report the results of a double-blind placebo-controlled study on the effect of an adenosine A1 receptor antagonist, FK352, on the incidence of dialysis hypotension in hypotension-prone patients.
Franssen, CMF, Franssen, CMF; id_orcid, Franssen, C.F.M.   +2 more
core   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Anesthetic complications in diabetic dogs subjected to phacoemulsification

Pesquisa Veterinária Brasileira
: The aim of this paper was to compare the incidence of anesthetic complications in diabetic and nondiabetic dogs subjected to phacoemulsification. In total, 30 male and female dogs of different breeds were used. The dogs were distributed into two groups:
Paula F. Pacheco, Viviane S. Galeazzi, Geni C.F. Patrício, Patrícia B. Flôr, Angélica V. Safatle, Silvia R.G. Cortopassi   +5 more
doaj   +1 more source